Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy (Q33670282)

28 July 2017

Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy (English)

1 reference

28 July 2017

0 references

Paula Desplats

3

0 references

Leslie Crews

object named as

Leslie Crews

1

0 references

Edward Rockenstein

6

object named as

Edward Rockenstein

1 reference

28 July 2017

10

Eliezer Masliah

1 reference

28 July 2017

Brian Spencer

2

1 reference

28 July 2017

Christina Patrick

4

1 reference

28 July 2017

Amy Paulino

5

1 reference

28 July 2017

Lawrence Hansen

7

1 reference

28 July 2017

Anthony Adame

8

1 reference

28 July 2017

Douglas Galasko

9

1 reference

28 July 2017

language of work or name

English

0 references

publication date

19 February 2010

1 reference

28 July 2017

1 reference

28 July 2017

5

1 reference

28 July 2017

e9313

1 reference

28 July 2017

2

1 reference

Creative Commons Attribution 4.0 International

28 July 2017

start time

19 February 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageQuant

object named as

ImageQuant

2 references

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2824828/fullTextXML

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

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Inhibition of autophagy induction delays neuronal cell loss caused by dysfunctional ESCRT-III in frontotemporal dementia

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Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy

21 June 2018

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Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

21 June 2018

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Nutrient-dependent regulation of autophagy through the target of rapamycin pathway.

21 June 2018

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Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases

21 June 2018

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Small molecule enhancers of autophagy for neurodegenerative diseases

21 June 2018

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Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species

21 June 2018

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Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

21 June 2018

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The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

21 June 2018

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Organization of the pre-autophagosomal structure responsible for autophagosome formation

21 June 2018

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Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

21 June 2018

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DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers

21 June 2018

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Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death

21 June 2018

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Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications

21 June 2018

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Cortical Lewy body disease and Parkinson's disease dementia.

21 June 2018

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Lysosomal system pathways: genes to neurodegeneration in Alzheimer's disease

21 June 2018

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Alzheimer disease with amygdala Lewy bodies: a distinct form of alpha-synucleinopathy

21 June 2018

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ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)

21 June 2018

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Autophagic stress in neuronal injury and disease.

21 June 2018

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 June 2018

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Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

21 June 2018

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Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

21 June 2018

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Alpha-synuclein-positive structures induced in leupeptin-infused rats

21 June 2018

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Lysosomal pathology associated with alpha-synuclein accumulation in transgenic models using an eGFP fusion protein.

21 June 2018

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Eating oneself and uninvited guests: autophagy-related pathways in cellular defense

21 June 2018

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Death by design: apoptosis, necrosis and autophagy

21 June 2018

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Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 June 2018

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Are Parkinson's disease with dementia and dementia with Lewy bodies the same entity?

21 June 2018

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Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration

21 June 2018

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 June 2018

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Autophagy: in sickness and in health

21 June 2018

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Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

21 June 2018

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21 June 2018

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Abeta1-42 promotes cholinergic sprouting in patients with AD and Lewy body variant of AD.

21 June 2018

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Alpha-synuclein up-regulates expression of caveolin-1 and down-regulates extracellular signal-regulated kinase activity in B103 neuroblastoma cells: role in the pathogenesis of Parkinson's disease

21 June 2018

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Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis--an approach for slowing Alzheimer disease?

21 June 2018

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Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

21 June 2018

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The neuropathogenic contributions of lysosomal dysfunction

21 June 2018

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Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

21 June 2018

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Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

21 June 2018

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Autophagy in neurons: a review

21 June 2018

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Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

21 June 2018

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Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection

21 June 2018

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

21 June 2018

1 reference

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Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease

21 June 2018

1 reference

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beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

21 June 2018

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Alpha-synuclein and the Lewy body disorders

21 June 2018

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Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

21 June 2018

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Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult

21 June 2018

1 reference

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Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein

21 June 2018

1 reference

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Autophagy as a regulated pathway of cellular degradation

21 June 2018

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Spectrum of Parkinson's disease, Parkinson's dementia, and Lewy body dementia.

21 June 2018

1 reference

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Pathoanatomy of Parkinson's disease

21 June 2018

1 reference

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High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

21 June 2018

1 reference

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 June 2018

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Frontal cortical synaptophysin in Lewy body diseases: relation to Alzheimer's disease and dementia

21 June 2018

1 reference

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Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop

21 June 2018

1 reference

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In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 June 2018

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Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

21 June 2018

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Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor protein

21 June 2018

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Neuropathological stageing of Alzheimer-related changes

21 June 2018

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Neurodegenerative disease: amyloid pores from pathogenic mutations.

21 June 2018

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Does striatal pathology distinguish Parkinson disease with dementia and dementia with Lewy bodies?

21 January 2018

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Cognitive profiles of individual patients with Parkinson's disease and dementia: comparison with dementia with lewy bodies and Alzheimer's disease.

21 January 2018

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Interaction between Abeta peptide and alpha synuclein: molecular mechanisms in overlapping pathology of Alzheimer's and Parkinson's in dementia with Lewy body disease.

21 January 2018

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Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

21 January 2018

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Involvement of macroautophagy in the dissolution of neuronal inclusions.

21 January 2018

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Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease

21 January 2018

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Aberrant phosphorylation of alpha-synuclein in human Niemann-Pick type C1 disease

21 January 2018

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Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

21 January 2018

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Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

21 January 2018

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Design and cloning of lentiviral vectors expressing small interfering RNAs

21 January 2018

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Subcellular localization of angiotensin II in kidney and adrenal

21 January 2018

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α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

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Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement

21 January 2018

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Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.

21 January 2018

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Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.

21 January 2018

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Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop.

21 January 2018

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Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.

30 October 2018

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Neuropathology of Alzheimer's disease: a critical update.

30 October 2018

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Entorhinal neurofibrillary tangles in Alzheimer disease with Lewy bodies

30 October 2018

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Gaucher disease associated with parkinsonism: four further case reports

30 October 2018

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PubMed

12 December 2020

The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes

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PubMed

12 December 2020

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Gaucher disease and parkinsonism: a phenotypic and genotypic characterization

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12 December 2020

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Identifiers

DOI

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference