Down-regulation of S1P1 receptor surface expression by protein kinase C inhibition (Q33673614)

28 July 2017

Down-regulation of S1P1 receptor surface expression by protein kinase C inhibition (English)

1 reference

28 July 2017

Sven-Christian Sensken

series ordinal

1

1 reference

PubMed ID

20032465

28 July 2017

Markus H Gräler

series ordinal

2

1 reference

PubMed ID

20032465

28 July 2017

language of work or name

English

0 references

publication date

23 December 2009

1 reference

Journal of Biological Chemistry

28 July 2017

1 reference

28 July 2017

285

1 reference

28 July 2017

9

1 reference

28 July 2017

6298-6307

1 reference

Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Finding a way out: lymphocyte egress from lymphoid organs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Functional PKC in vivo analysis using deficient mouse models

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Tipping the gatekeeper: S1P regulation of endothelial barrier function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

FTY720 (fingolimod) in renal transplantation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

FTY720: a promising agent for treatment of metastatic hepatocellular carcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Regulation of protein kinase C by sphingosine and lysosphingolipids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825425

Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Accumulation of fingolimod (FTY720) in lymphoid tissues contributes to prolonged efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Oral fingolimod (FTY720) in multiple sclerosis: two-year results of a phase II extension study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

FTY720 versus mycophenolate mofetil in de novo renal transplantation: six-month results of a double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Dimethylsphingosine and FTY720 inhibit the SK1 form but activate the SK2 form of sphingosine kinase from rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Protein kinase C epsilon dependence of the recovery from down-regulation of S1P1 G protein-coupled receptors of T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Discontinued postnatal thymocyte development in sphingosine 1-phosphate-lyase-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Distinctive T cell-suppressive signals from nuclearized type 1 sphingosine 1-phosphate G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Transient FTY720 treatment promotes immune-mediated clearance of a chronic viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.049692

Immunosuppressant FTY720 inhibits thymocyte emigration

21 January 2018

1 reference

12 December 2020

A potential role for CD69 in thymocyte emigration

1 reference

12 December 2020

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets

1 reference

12 December 2020

A three-step purification procedure for protein kinase C: characterization of the purified enzyme

1 reference

12 December 2020

Mechanism of protein kinase C inhibition by sphingosine

1 reference

12 December 2020

A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor

1 reference

12 December 2020

Deal watch: Bristol-Myers Squibb and Exelixis collaborate on kinase inhibitors

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.049692

1 reference

28 July 2017

1 reference

28 July 2017

1 reference

PubMed ID

20032465