A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo. (Q33677482)

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15 January 2020

title

A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo (English)

1 reference

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15 January 2020

author name string

Thomas Fehr

1

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15 January 2020

Josef Kurtz

3

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15 January 2020

Takashi Onoe

4

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15 January 2020

Guiling Zhao

5

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15 January 2020

Timothy Hogan

6

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15 January 2020

Casey Vallot

7

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15 January 2020

Megan Sykes

9

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15 January 2020

language of work or name

English

0 references

publication date

10 December 2009

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15 January 2020

1 reference

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15 January 2020

volume

115

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15 January 2020

issue

6

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15 January 2020

page(s)

1280-1287

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Clinical experience with mixed chimerism to induce transplantation tolerance

15 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

NFATc1 regulates PD-1 expression upon T cell activation.

14 July 2018

1 reference

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Mechanisms underlying blockade of allograft acceptance by TLR ligands

14 July 2018

1 reference

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Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

HLA-mismatched renal transplantation without maintenance immunosuppression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

FOXP3 controls regulatory T cell function through cooperation with NFAT

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Peripheral tolerance of CD8 T lymphocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Transcriptional regulation by calcium, calcineurin, and NFAT

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Interferon gamma is required for activation-induced death of T lymphocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Transcriptional mechanisms underlying lymphocyte tolerance.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Partners in transcription: NFAT and AP-1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

An enhanced immune response in mice lacking the transcription factor NFAT1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Reciprocal NFAT1 and NFAT2 nuclear localization in CD8+ anergic T cells is regulated by suboptimal calcium signaling.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: in vivo and in vitro analyses.

30 October 2018

1 reference

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Early regulation of CD8 T cell alloreactivity by CD4+CD25- T cells in recipients of anti-CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor-reactive CD8+ T cells, precluding a role for sustained regulation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Lack of role for CsA-sensitive or Fas pathways in the tolerization of CD4 T cells via BMT and anti-CD40L.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826238

Effects of cyclosporine on transplant tolerance: the role of IL-2

30 October 2018

1 reference

12 December 2020

Deletion of Naive CD8 T Cells Requires Persistent Antigen and Is Not Programmed by an Initial Signal from the Tolerogenic APC

1 reference

12 December 2020

Earlier low-dose TBI or DST overcomes CD8+ T-cell-mediated alloresistance to allogeneic marrow in recipients of anti-CD40L

1 reference

12 December 2020

Cyclosporin A-induced autologous graft-versus-host disease: a prototypical model of autoimmunity and active (dominant) tolerance coordinately induced by recent thymic emigrants

1 reference

12 December 2020

Graft tolerance: a duel of two signals

1 reference

12 December 2020

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1 reference

12 December 2020

IFN-gamma production by CD8+ T cells depends on NFAT1 transcription factor and regulates Th differentiation

1 reference

12 December 2020

10.1182/BLOOD-2009-07-230680

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20007805%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20007805%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

20007805

1 reference