Partners in transcription: NFAT and AP-1. (Q34279371)

1 August 2017

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title

Partners in transcription: NFAT and AP-1. (English)

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1 August 2017

1

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1 August 2017

López-Rodríguez C

2

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1 August 2017

Rao A

series ordinal

3

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1 August 2017

language of work or name

English

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publication date

1 April 2001

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1 August 2017

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1 August 2017

20

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1 August 2017

2476-2489

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1 August 2017

19

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204386

1 August 2017

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cites work

Protein kinase Ctheta: a new essential superstar on the T-cell stage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

T cell differentiation: a mechanistic view

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Role of transcriptional repressor ICER in cyclic AMP-mediated attenuation of cytokine gene expression in human thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Regulation of gene expression by hypertonicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Characterization of P5, a novel NFAT/AP-1 site in the human IL-4 promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Integration of calcium and cyclic AMP signaling pathways by 14-3-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

c-Jun NH(2)-terminal kinase inhibits targeting of the protein phosphatase calcineurin to NFATc1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Requirement for transcription factor NFAT in interleukin-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

The human granulocyte-macrophage colony-stimulating factor gene is autonomously regulated in vivo by an inducible tissue-specific enhancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Molecular basis of cooperative DNA bending and oriented heterodimer binding in the NFAT1-Fos-Jun-ARRE2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

JNK is required for effector T-cell function but not for T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

A T cell-specific enhancer in the interleukin-3 locus is activated cooperatively by Oct and NFAT elements within a DNase I-hypersensitive site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Stimulus-specific assembly of enhancer complexes on the tumor necrosis factor alpha gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Impaired NFAT regulation and its role in a severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Abnormal differentiation of thymocytes in mice treated with cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Two-site interaction of nuclear factor of activated T cells with activated calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

NF-AT-Driven interleukin-4 transcription potentiated by NIP45

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Transcriptional regulation of the IL-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Manipulating immune responses with immunosuppressive agents that target NFAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Rapid targeting of nuclear proteins to the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

NF-AT5: the NF-AT family of transcription factors expands in a new direction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Mechanisms of transactivation by nuclear factor of activated T cells-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Interaction of calcineurin with a domain of the transcription factor NFAT1 that controls nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription factor NFAT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Impaired negative selection in CD28-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

NF-AT-AP-1 and Rel-bZIP: hybrid vigor and binding under the influence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

NF-AT components define a family of transcription factors targeted in T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

The transcription factor NFAT4 is involved in the generation and survival of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

NFATz: a novel rel similarity domain containing protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Phosphorylation of the transcription factor NFATp inhibits its DNA binding activity in cyclosporin A-treated human B and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

A second calcineurin binding site on the NFAT regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Identification of amino acid residues and protein kinases involved in the regulation of NFATc subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

The transcription factor NF-ATc is essential for cardiac valve formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Transcription factors of the NFAT family: regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

B7 blockade prevents activation-induced cell death of thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

The interleukin 2 receptor alpha chain/CD25 promoter is a target for nuclear factor of activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Dual role of the nuclear factor of activated T cells insert region in DNA recognition and cooperative contacts to activator protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

A novel transcription factor, T-bet, directs Th1 lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Solution structure of the core NFATC1/DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

CBP/p300 Integrates Raf/Rac-Signaling Pathways in the Transcriptional Induction of NF-ATc during T Cell Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Defective T Cell Differentiation in the Absence of Jnk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

An Essential Role of the Nuclear Factor of Activated T Cells in the Regulation of the Expression of the Cyclooxygenase-2 Gene in Human T Lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

Reconstitution of T cell-specific transcription directed by composite NFAT/Oct elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATp

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

A role for the p38 MAP kinase pathway in the nuclear shuttling of NFATp

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

Blocked Ras activation in anergic CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

Requirement for integration of phorbol 12-myristate 13-acetate and calcium pathways is preserved in the transactivation domain of NFAT1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

Effects of a constitutively active form of calcineurin on T cell activation and thymic selection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

The regulation of CD95 (Fas) ligand expression in primary T cells: induction of promoter activation in CD95LP-Luc transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

NFATc1 and NFATc2 together control both T and B cell activation and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204386

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204386

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference