Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies (Q33686907)

24910634

28 July 2017

title

Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies (English)

1 reference

28 July 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24910634%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Pierre Bruhns

series ordinal

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24910634%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Aurélie Gouel-Chéron

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24910634%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Friederike Jönsson

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24910634%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

1 reference

30 May 2014

1 reference

24910634

28 July 2017

published in

Frontiers in Immunology

1 reference

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7 June 2020

volume

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24910634%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

254

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24910634%20AND%20SRC:MED&resulttype=core&format=json

The function of Fcγ receptors in dendritic cells and macrophages

7 June 2020

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21 June 2018

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CalDAG-GEFI deficiency protects mice in a novel model of Fcγ RIIA-mediated thrombosis and thrombocytopenia

21 June 2018

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Functional FCGR2B gene variants influence intravenous immunoglobulin response in patients with Kawasaki disease

21 June 2018

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21 June 2018

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21 June 2018

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Association of FcγRIIa R131H polymorphism with idiopathic pulmonary fibrosis severity and progression

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake

21 June 2018

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Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases

21 June 2018

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21 June 2018

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Fcgamma receptors as regulators of immune responses

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling.

21 June 2018

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21 June 2018

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21 June 2018

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A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling

21 June 2018

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Association of Fcgamma receptor IIb and IIIb polymorphisms with susceptibility to systemic lupus erythematosus in Thais.

21 June 2018

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Involvement of Fc gamma receptor polymorphism in the therapeutic response of idiopathic thrombocytopenic purpura

21 June 2018

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Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcgammaRIIA.

21 June 2018

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FcgammaRIIa/IIIa polymorphism and its association with clinical manifestations in Korean lupus patients

21 June 2018

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Polymorphisms in inflammatory cytokines and Fcgamma receptors in childhood chronic immune thrombocytopenic purpura: a pilot study

21 June 2018

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21 June 2018

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21 June 2018

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Thrombosis and shock induced by activating antiplatelet antibodies in human Fc gamma RIIA transgenic mice: the interplay among antibody, spleen, and Fc receptor

21 June 2018

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Variant genotypes of the low-affinity Fcgamma receptors in two control populations and a review of low-affinity Fcgamma receptor polymorphisms in control and disease populations.

21 June 2018

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Protein-protein interactions between native Ro52 and immunoglobulin G heavy chain

21 June 2018

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The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: a transgenic mouse model

21 June 2018

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Correlation of platelet Fc gammaRIIA polymorphism in refractory idiopathic (immune) thrombocytopenic purpura

21 June 2018

1 reference

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Expression of functional CD32 molecules on human NK cells is determined by an allelic polymorphism of the FcgammaRIIC gene.

21 June 2018

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Increased potency of Fc-receptor-targeted antigens

21 June 2018

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A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease

21 June 2018

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21 June 2018

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Beta 2 (CD11/CD18) integrins can serve as signaling partners for other leukocyte receptors

21 June 2018

1 reference

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Characterization of a new alloantigen (SH) on the human neutrophil Fc gamma receptor IIIb.

21 June 2018

1 reference

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Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

21 June 2018

1 reference

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Reconstitution of human Fc gamma RIII cell type specificity in transgenic mice

21 June 2018

1 reference

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FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo

21 June 2018

1 reference

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Antigen targeting to myeloid-specific human Fc gamma RI/CD64 triggers enhanced antibody responses in transgenic mice

21 June 2018

1 reference

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Cytotoxic antibodies trigger inflammation through Fc receptors

21 June 2018

1 reference

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An Fc receptor structurally related to MHC class I antigens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038777

Sequences of complementary DNAs that encode the NA1 and NA2 forms of Fc receptor III on human neutrophils

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038777

Molecular basis for a polymorphism of human Fc gamma receptor II (CD32)

21 June 2018

1 reference

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The glycosyl phosphatidylinositol-linked Fc gamma RIIIPMN mediates transmembrane signaling events distinct from Fc gamma RII.

21 June 2018

1 reference

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Biallelic neutrophil Na-antigen system is associated with a polymorphism on the phospho-inositol-linked Fc gamma receptor III (CD16).

21 June 2018

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21 June 2018

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21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038777

Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038777

Allelic polymorphisms of human Fc gamma receptor IIA and Fc gamma receptor IIIB. Independent mechanisms for differences in human phagocyte function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038777

On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038777

Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses.

21 June 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Human basophils express the glycosylphosphatidylinositol-anchored low-affinity IgG receptor FcgammaRIIIB (CD16B).

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. I. Regulatory FCGR2B polymorphisms and their association with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Ethnic variation in frequency of an allelic polymorphism of human Fc gamma RIIA determined with allele specific oligonucleotide probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Association between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

FCGR3A-158 polymorphism influences the biological response to infliximab in Crohn's disease through affecting the ADCC activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Fcgamma receptor type IIIA polymorphisms influence treatment outcomes in patients with inflammatory arthritis treated with tumor necrosis factor alpha-blocking agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Fc gamma receptor IIa (CD32) heterogeneity in patients with recurrent bacterial respiratory tract infections

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Role of the Fcgamma receptor IIA polymorphism in the antiphospholipid syndrome: an international meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

FcgammaRIIa-131R allele and FcgammaRIIIa-176V/V genotype are risk factors for progression of IgA nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Evidence that deletion at FCGR3B is a risk factor for systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

A human Fc gamma RI/CD64 transgenic model for in vivo analysis of (bispecific) antibody therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

GA201 (RG7160): a novel, humanized, glycoengineered anti-EGFR antibody with enhanced ADCC and superior in vivo efficacy compared with cetuximab

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

A novel human CD32 mAb blocks experimental immune haemolytic anaemia in FcgammaRIIA transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Association of Fcgamma receptor polymorphisms with adult onset Still's disease in Korea

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038777

FcgammaRIIa, IIIa and IIIb gene polymorphisms in Behçet's disease: do they have any clinical implications?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038777

Fcgamma receptor polymorphisms in Wegener's granulomatosis: risk factors for disease relapse

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038777

Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts

30 October 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Fcγ receptor type IIIA genotype and response to tumor necrosis factor α–blocking agents in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Genetic linkage and association of Fc? receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00254

Fcγ receptor type IIIA polymorphism influences treatment outcomes in patients with rheumatoid arthritis treated with rituximab

21 January 2018

1 reference

12 December 2020

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene

1 reference

12 December 2020

FcRn: an IgG receptor on phagocytes with a novel role in phagocytosis

1 reference

12 December 2020

The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs

1 reference

12 December 2020

Role of the Fcgamma receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis

1 reference

12 December 2020

Severity of Guillain-Barré syndrome is associated with Fc gamma Receptor III polymorphisms

1 reference

12 December 2020

Evidence for linkage disequilibrium between Fcgamma RIIIa-V158F and Fcgamma RIIa-H131R polymorphisms in white patients, and for an Fcgamma RIIIa-restricted influence on the response to therapeutic antibodies

1 reference

12 December 2020

Neutrophil FcgammaRIIIb allelic polymorphism in anti-neutrophil cytoplasmic antibody (ANCA)-positive systemic vasculitis

1 reference

12 December 2020

Fcgamma receptor polymorphisms in systemic lupus erythematosus: association with disease and in vivo clearance of immune complexes

1 reference

12 December 2020

Antibody-mediated coengagement of FcγRIIb and B cell receptor complex suppresses humoral immunity in systemic lupus erythematosus

1 reference

12 December 2020

Fcgamma receptor type IIIA is associated with rheumatoid arthritis in two distinct ethnic groups

1 reference

12 December 2020

Immunoglobulin G Fc-receptor (FcgammaR) IIA and IIIB polymorphisms related to disability in MS

1 reference

12 December 2020

IgG receptor IIa alleles determine susceptibility and severity of Guillain-Barré syndrome

1 reference

12 December 2020

Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus

1 reference

12 December 2020

Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility

1 reference

12 December 2020

Fc gamma RIIIB gene duplication: evidence for presence and expression of three distinct Fc gamma RIIIB genes in NA(1+,2+)SH(+) individuals

1 reference

12 December 2020

Association of Fc gamma receptor IIIB, but not of Fc gamma receptor IIA and IIIA polymorphisms with systemic lupus erythematosus in Japanese

1 reference

12 December 2020

Associations between FCGR3A polymorphisms and susceptibility to rheumatoid arthritis: a metaanalysis

1 reference

12 December 2020

beta2-microglobulin dependence of the lupus-like autoimmune syndrome of MRL-lpr mice

1 reference

12 December 2020

FcgammaRIIA and FcgammaRIIIB polymorphisms in myasthenia gravis

1 reference

12 December 2020

Fcγ receptors inhibit mouse and human basophil activation

1 reference

12 December 2020

Fc optimization of therapeutic antibodies enhances their ability to kill tumor cells in vitro and controls tumor expansion in vivo via low-affinity activating Fcgamma receptors

1 reference

12 December 2020

FCGR2B gene polymorphism rather than FCGR2A, FCGR3A and FCGR3B is associated with anti-GBM disease in Chinese

1 reference

12 December 2020

Targeting weak antigens to CD64 elicits potent humoral responses in human CD64 transgenic mice

1 reference

12 December 2020

A single amino acid in the second Ig-like domain of the human Fc gamma receptor II is critical for human IgG2 binding

1 reference

12 December 2020

Analysis of FcgammaRII gene polymorphisms in Wegener's granulomatosis

1 reference

12 December 2020

Overrepresentation of the Fcgamma receptor type IIA R131/R131 genotype in caucasoid systemic lupus erythematosus patients with autoantibodies to C1q and glomerulonephritis

1 reference

12 December 2020

Resolution of cutaneous inflammation after local elimination of macrophages

1 reference

12 December 2020

Expression of a functional high-affinity IgG receptor, Fc gamma RI, on human mast cells: Up-regulation by IFN-gamma

1 reference

12 December 2020

Association of the leukocyte immunoglobulin G (Fcgamma) receptor IIIa-158V/F polymorphism with inflammatory myopathies in Dutch patients

1 reference

12 December 2020

Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease

1 reference

12 December 2020

The Fc gammaRIIIA-158F allele is a risk factor for systemic lupus erythematosus

1 reference

12 December 2020

The Fc gammaRIIa polymorphism in Turkish children with asthma bronchial and allergic rhinitis

1 reference

12 December 2020

Copy Number Variation of FCGR3B Is Associated with Susceptibility to Idiopathic Pulmonary Fibrosis

1 reference

12 December 2020

Transgenic mice expressing human FcgammaRIIa have enhanced sensitivity to induced autoimmune arthritis as well as elevated Th17 cells

1 reference

12 December 2020

Involvement of Fcgamma receptor IIIA genotypes in susceptibility to rheumatoid arthritis

1 reference

12 December 2020

Antibodies to C1q in systemic lupus erythematosus: characteristics and relation to Fc gamma RIIA alleles

1 reference

12 December 2020

CD64-directed immunotoxin inhibits arthritis in a novel CD64 transgenic rat model

1 reference

12 December 2020

Development of spontaneous multisystem autoimmune disease and hypersensitivity to antibody-induced inflammation in Fcgamma receptor IIa-transgenic mice

1 reference

12 December 2020

NA1/NA2 heterozygote of Fcgr3b is a risk factor for progression of IgA nephropathy in Chinese

1 reference

12 December 2020

Skewed distribution of IgG Fc receptor IIa (CD32) polymorphism is associated with renal disease in systemic lupus erythematosus patients

1 reference

12 December 2020

Haplotypes of FcγRIIa and FcγRIIIb polymorphic variants influence IgG-mediated responses in neutrophils

1 reference

12 December 2020

Cutting Edge: The murine high-affinity IgG receptor FcγRIV is sufficient for autoantibody-induced arthritis

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2014.00254

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24910634%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24910634%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

24910634

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24910634%20AND%20SRC:MED&resulttype=core&format=json