Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model. (Q33688390)

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English	Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model.	scientific article

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13 March 2020

Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model (English)

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13 March 2020

hepatocellular carcinoma

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based on heuristic

inferred from title

10

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13 March 2020

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Kodappully Sivaraman Siveen

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13 March 2020

Kwang Seok Ahn

2

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13 March 2020

Tina H Ong

3

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13 March 2020

Muthu K Shanmugam

4

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13 March 2020

Feng Li

5

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13 March 2020

Wei Ney Yap

6

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13 March 2020

Alan Prem Kumar

7

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13 March 2020

Chee Wai Fong

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13 March 2020

Vinay Tergaonkar

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13 March 2020

Gautam Sethi

11

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13 March 2020

language of work or name

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publication date

1 April 2014

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13 March 2020

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13 March 2020

5

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13 March 2020

7

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13 March 2020

1897-1911

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13 March 2020

Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma

1 reference

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21 June 2018

Tocotrienol research: past into present.

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21 June 2018

Angiogenesis in hepatocellular carcinoma: a potential target for chemoprevention and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4039111

21 June 2018

Molecular targeted therapies in hepatocellular carcinoma

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21 June 2018

AKT as locus of cancer angiogenic robustness and fragility

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21 June 2018

First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway.

1 reference

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21 June 2018

Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer

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21 June 2018

Tocotrienol as a potential anticancer agent

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21 June 2018

Basic and therapeutic aspects of angiogenesis

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21 June 2018

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

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21 June 2018

Tocotrienols: inflammation and cancer

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21 June 2018

The 21st century form of vitamin E--tocotrienol

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21 June 2018

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

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21 June 2018

Molecular mechanisms and clinical applications of angiogenesis

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21 June 2018

Palm tocotrienols decrease levels of pro-angiogenic markers in human umbilical vein endothelial cells (HUVEC) and murine mammary cancer cells

1 reference

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21 June 2018

Antiangiogenic agents in advanced gastrointestinal malignancies: past, present and a novel future

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21 June 2018

γ-Tocotrienol inhibits angiogenesis of human umbilical vein endothelial cell induced by cancer cell

1 reference

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21 June 2018

γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4039111

21 June 2018

Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases

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21 June 2018

P70S6K 1 regulation of angiogenesis through VEGF and HIF-1alpha expression

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21 June 2018

The mTOR pathway: a new target in cancer therapy.

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21 June 2018

Chick ex ovo culture and ex ovo CAM assay: how it really works

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21 June 2018

Id1, inhibitor of differentiation, is a key protein mediating anti-tumor responses of gamma-tocotrienol in breast cancer cells

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21 June 2018

Alpha-, gamma- and delta-tocopherols reduce inflammatory angiogenesis in human microvascular endothelial cells

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21 June 2018

Suppression of tumor growth by palm tocotrienols via the attenuation of angiogenesis

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21 June 2018

Inhibitory effects of gamma-tocotrienol on invasion and metastasis of human gastric adenocarcinoma SGC-7901 cells

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21 June 2018

Antiangiogenic and anticancer potential of unsaturated vitamin E (tocotrienol).

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21 June 2018

Gamma-tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways

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21 June 2018

Tocotrienol inhibits secretion of angiogenic factors from human colorectal adenocarcinoma cells by suppressing hypoxia-inducible factor-1alpha.

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21 June 2018

Natural products as leads to potential drugs: an old process or the new hope for drug discovery?

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21 June 2018

Understanding the biology of angiogenesis: review of the most important molecular mechanisms

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21 June 2018

Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4039111

21 June 2018

Down-regulation of telomerase activity in DLD-1 human colorectal adenocarcinoma cells by tocotrienol

1 reference

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21 June 2018

Angiogenesis as a therapeutic target

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21 June 2018

Angiogenesis in life, disease and medicine

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21 June 2018

Modulation of microvascular growth and morphogenesis by reconstituted basement membrane gel in three-dimensional cultures of rat aorta: A comparative study of angiogenesis in Matrigel, collagen, fibrin, and plasma clot

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21 June 2018

Notoginsenoside Ft1 promotes angiogenesis via HIF-1α mediated VEGF secretion and the regulation of PI3K/AKT and Raf/MEK/ERK signaling pathways.

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30 October 2018

Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo.

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30 October 2018

γ-Tocotrienol inhibits cell viability through suppression of β-catenin/Tcf signaling in human colon carcinoma HT-29 cells.

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30 October 2018

In vivo matrigel migration and angiogenesis assays.

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30 October 2018

The role of VEGF pathways in human physiologic and pathologic angiogenesis.

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Tube formation: an in vitro matrigel angiogenesis assay.

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30 October 2018

VEGF function for upregulation of endogenous PlGF expression during FGF-2-mediated therapeutic angiogenesis.

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30 October 2018

Establishment of a hepatocellular carcinoma cell line with unique metastatic characteristics through in vivo selection and screening for metastasis-related genes through cDNA microarray

1 reference

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12 December 2020

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Inhibition of K562 leukemia angiogenesis and growth by selective Na+/H+ exchanger inhibitor cariporide through down-regulation of pro-angiogenesis factor VEGF

1 reference

https://pubmed.ncbi.nlm.nih.gov/24722367

12 December 2020

based on heuristic

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10.18632/ONCOTARGET.1876

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13 March 2020

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13 March 2020

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13 March 2020

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