AKT as locus of cancer angiogenic robustness and fragility (Q38010111)

26 August 2017

AKT as locus of cancer angiogenic robustness and fragility (English)

1 reference

26 August 2017

Ziv Radisavljevic

1

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26 August 2017

1 January 2013

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Journal of Cellular Physiology

26 August 2017

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26 August 2017

228

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26 August 2017

1

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26 August 2017

21-24

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Contribution of bone microenvironment to leukemogenesis and leukemia progression

26 August 2017

1 reference

Modes of resistance to anti-angiogenic therapy

21 January 2018

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Role of soluble mediators in angiogenesis

21 January 2018

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Highly optimized tolerance: a mechanism for power laws in designed systems

21 January 2018

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Complexity and robustness

21 January 2018

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Reverse engineering of biological complexity

21 January 2018

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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

21 January 2018

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Activation of Akt, not connexin 43 protein ubiquitination, regulates gap junction stability

21 January 2018

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Tumor angiogenesis: therapeutic implications

21 January 2018

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Angiogenesis in cancer, vascular, rheumatoid and other disease

21 January 2018

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21 January 2018

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Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization

21 January 2018

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Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

21 January 2018

1 reference

VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

21 January 2018

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

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Lymphoma cell VEGFR2 expression detected by immunohistochemistry predicts poor overall survival in diffuse large B cell lymphoma treated with immunochemotherapy (R-CHOP).

21 January 2018

1 reference

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

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Hypoxia--a key regulatory factor in tumour growth

21 January 2018

1 reference

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

21 January 2018

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Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer

21 January 2018

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Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: a potential strategy for plaque stabilization

21 January 2018

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Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes

21 January 2018

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The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma

21 January 2018

1 reference

Angiogenesis in acute promyelocytic leukemia: induction by vascular endothelial growth factor and inhibition by all-trans retinoic acid

21 January 2018

1 reference

A simple physical model for binding energy hot spots in protein-protein complexes

21 January 2018

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A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer.

21 January 2018

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Vascular endothelial growth factor expression and capillary architecture in high-grade PIN and prostate cancer in untreated and androgen-ablated patients

21 January 2018

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Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

21 January 2018

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Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

21 January 2018

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Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

21 January 2018

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The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications

21 January 2018

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The shunt problem: control of functional shunting in normal and tumour vasculature.

21 January 2018

1 reference

Nitric oxide suppression triggers apoptosis through the FKHRL1 (FOXO3A)/ROCK kinase pathway in human breast carcinoma cells

21 January 2018

1 reference

Locus of fragility in robust breast cancer system

21 January 2018

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Inactivated tumor suppressor Rb by nitric oxide promotes mitosis in human breast cancer cells

21 January 2018

1 reference

AKT as locus of fragility in robust cancer system

21 January 2018

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Signaling through Cdk2, importin-alpha and NuMA is required for H2O2-induced mitosis in primary type II pneumocytes

21 January 2018

1 reference

TOR kinase and Ran are downstream from PI3K/Akt in H2O2-induced mitosis

21 January 2018

1 reference

Vascular endothelial growth factor up-regulates ICAM-1 expression via the phosphatidylinositol 3 OH-kinase/AKT/Nitric oxide pathway and modulates migration of brain microvascular endothelial cells

21 January 2018

1 reference

Circulating endothelial precursors: mystery, reality, and promise

21 January 2018

1 reference

Targeting angiogenesis: a novel, rational therapeutic approach for non-Hodgkin lymphoma

21 January 2018

1 reference

Angiogenesis and antiangiogenic therapy in non-Hodgkin's lymphoma

21 January 2018

1 reference

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

21 January 2018

1 reference

Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC.

21 January 2018

1 reference

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

21 January 2018

1 reference

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

21 January 2018

1 reference

Scatter-factor and semaphorin receptors: cell signalling for invasive growth

21 January 2018

1 reference

Angiogenesis in nodal B cell lymphomas: a high throughput study.

21 January 2018

1 reference

Role of phosphatidylinositol 3'-kinase/AKT pathway in diffuse large B-cell lymphoma survival

21 January 2018

1 reference

Hydrogen peroxide inhibits gap junctional intercellular communication in glutathione sufficient but not glutathione deficient cells.

21 January 2018

1 reference

Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways

21 January 2018

1 reference

Antiangiogenesis drug design: multiple pathways targeting tumor vasculature

21 January 2018

1 reference

Mutation, specialization, and hypersensitivity in highly optimized tolerance

21 January 2018

1 reference

KDR receptor: a key marker defining hematopoietic stem cells

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCP.24115

1 reference

release_mi626c66r5f3jjywquuifh3w5u

26 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mi626c66r5f3jjywquuifh3w5u

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

22585603

1 reference

PubMed ID

22585603