APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure (Q33691358)

28 July 2017

APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure (English)

1 reference

28 July 2017

3

Thomas J Montine

1 reference

28 July 2017

Lynn M Bekris

1

1 reference

28 July 2017

Nichole M Galloway

series ordinal

2

1 reference

28 July 2017

Gerard D Schellenberg

series ordinal

4

1 reference

28 July 2017

Chang-En Yu

series ordinal

5

1 reference

28 July 2017

1 March 2010

1 reference

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

28 July 2017

1 reference

28 July 2017

153B

1 reference

28 July 2017

2

1 reference

28 July 2017

409-417

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2829359/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Expression of APP pathway mRNAs and proteins in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: patterns of linkage disequilibrium and disease/marker association

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Non-coding RNAs in the nervous system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Neuronal specific regulatory elements in apolipoprotein E gene proximal promoter.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Computational anatomy and neuropsychiatric disease: probabilistic assessment of variation and statistical inference of group difference, hemispheric asymmetry, and time-dependent change

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Specific regional transcription of apolipoprotein E in human brain neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

The neuropathological changes associated with normal brain aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Evolutionary duplication of a hepatic control region in the human apolipoprotein E gene locus. Identification of a second region that confers high level and liver-specific expression of the human apolipoprotein E gene in transgenic mice

21 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Reduced hippocampal functional connectivity in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Hippocampal apolipoprotein D level depends on Braak stage and APOE genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

In vivo imaging of region and cell type specific neocortical neurodegeneration in Alzheimer's disease. Perspectives of MRI derived corpus callosum measurement for mapping disease progression and effects of therapy. Evidence from studies with MRI, EE

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

APOE genotype, family history of dementia, and Alzheimer disease risk: a 6-year follow-up study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Contribution of APOE promoter polymorphisms to Alzheimer's disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Distortion of allelic expression of apolipoprotein E in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Variation at the APOE -491 promoter locus is associated with altered brain levels of apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Brain region-specific up-regulation of mouse apolipoprotein E by pharmacological estrogen treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Whole-brain atrophy rate in Alzheimer disease: identifying fast progressors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Regionally specific neuronal expression of human APOE gene in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

High expression of apolipoprotein E mRNA in the brains with sporadic Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

ADLAPH: A molecular haplotyping method based on allele-discriminating long-range PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Functional mitochondria are required for amyloid beta-mediated neurotoxicity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829359

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

30 October 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.B.30993

Apolipoprotein gene E4 allele promoter polymorphisms as risk factors for Alzheimer's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19554612

12 December 2020

inferred from PubMed ID database lookup

APOE epsilon 3/ epsilon 4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer's disease diagnosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19554612

12 December 2020

inferred from PubMed ID database lookup

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19554612

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1002/AJMG.B.30993

1 reference

release_fcow4p23wzhdfeyszgmxgi3sea

28 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fcow4p23wzhdfeyszgmxgi3sea

24 November 2022

mapped directly with Wikidata item

PMCID

2829359

1 reference

28 July 2017

1 reference