Pharmacokinetics of [18F]trovafloxacin in healthy human subjects studied with positron emission tomography (Q33695030)

28 July 2017

title

Pharmacokinetics of [18F]trovafloxacin in healthy human subjects studied with positron emission tomography (English)

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human subject research project

28 July 2017

main subject

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A J Fischman

1

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28 July 2017

J W Babich

2

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28 July 2017

A A Bonab

3

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28 July 2017

N M Alpert

4

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28 July 2017

J Vincent

5

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28 July 2017

R J Callahan

6

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28 July 2017

J A Correia

7

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28 July 2017

R H Rubin

8

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28 July 2017

language of work or name

English

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publication date

1 August 1998

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Antimicrobial Agents and Chemotherapy

28 July 2017

published in

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28 July 2017

volume

42

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28 July 2017

issue

8

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28 July 2017

page(s)

2048-2054

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Hepatobiliary elimination of trovafloxacin and metabolites following single oral doses in healthy volunteers.

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

In vitro activities of trovafloxacin against 557 strains of anaerobic bacteria.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Pharmacokinetics of [18F]fleroxacin in patients with acute exacerbations of chronic bronchitis and complicated urinary tract infection studied by positron emission tomography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Trovafloxacin is active against Toxoplasma gondii

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Dose-ranging study of CP-99,219 (trovafloxacin) for treatment of uncomplicated gonorrhea

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Pharmacokinetics and penetration into inflammatory fluid of trovafloxacin (CP-99,219).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Multiple-dose pharmacokinetics and safety of trovafloxacin in healthy volunteers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

In vivo efficacy of trovafloxacin (CP-99,219), a new quinolone with extended activities against gram-positive pathogens, Streptococcus pneumoniae, and Bacteroides fragilis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Pharmacokinetics and safety of trovafloxacin (CP-99,219), a new quinolone antibiotic, following administration of single oral doses to healthy male volunteers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

In vitro activity of CP-99,219, a new fluoroquinolone, against clinical isolates of gram-positive bacteria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Pharmacokinetics of 18F-labeled fluconazole in healthy human subjects by positron emission tomography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Pharmacokinetics of [18F]fleroxacin in healthy human subjects studied by using positron emission tomography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

In vitro antimicrobial activity of CP-99,219, a novel azabicyclo-naphthyridone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

In vitro activity of the new fluoroquinolone CP-99,219.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Activity of CP 99,219 compared with those of ciprofloxacin, grepafloxacin, metronidazole, cefoxitin, piperacillin, and piperacillin-tazobactam against 489 anaerobes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Quinolone antibiotics in therapy of experimental pneumococcal meningitis in rabbits

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

In vitro activity of a new fluoroquinolone, CP-99,219, against strains of Neisseria gonorrhoeae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Evaluation of CP-99,219, a new fluoroquinolone, for treatment of experimental penicillin- and cephalosporin-resistant pneumococcal meningitis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

The in-vitro activity of CP 99,219, a new naphthyridone antimicrobial agent: a comparison with fluoroquinolone agents

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Pharmacokinetics of 18F-labeled fluconazole in rabbits with candidal infections studied with positron emission tomography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Comparative activity of fluorinated quinolones in acute and subacute Streptococcus pneumoniae pneumonia models: efficacy of temafloxacin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Pharmacokinetics of 18F-labeled fleroxacin in rabbits with Escherichia coli infections, studied with positron emission tomography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Tissue pharmacokinetics of fleroxacin in humans as determined by positron emission tomography.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Pharmacokinetics of 18F-labeled trovafloxacin in normal and Escherichia coli-infected rats and rabbits studied with positron emission tomography

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

Comparative antimicrobial activity and spectrum of CP-99,219, a novel fluoroquinolone, tested against ciprofloxacin-resistant clinical isolates.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

In vitro activity of CP-99,219, a novel 7-(3-azabicyclo[3.1.0]hexyl) naphthyridone antimicrobial.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105732

The in-vitro activity of trovafloxacin and nine other antimicrobials against 413 anaerobic bacteria

30 October 2018

1 reference

12 December 2020

In vitro activity and selection of disk content for disk diffusion susceptibility tests with trovafloxacin

1 reference

12 December 2020

Activity of trovafloxacin against blood isolates of Streptococcus pneumoniae in Sweden

1 reference

12 December 2020

The average density of healthy lung

1 reference

12 December 2020

Comparative in-vitro activity of the new fluoroquinolone trovafloxacin (CP-99,219) against gram-positive cocci

1 reference

12 December 2020

In vitro activity of trovafloxacin versus ciprofloxacin against clinical isolates

1 reference

12 December 2020

Performance characteristics of an eight-ring whole body PET scanner

1 reference

12 December 2020

Activity of CP 99,219 (trovafloxacin) compared with ciprofloxacin, sparfloxacin, clinafloxacin, lomefloxacin and cefuroxime against ten penicillin-susceptible and penicillin-resistant pneumococci by time-kill methodology

1 reference

12 December 2020

Methods of measuring susceptibility of anaerobic bacteria to trovafloxacin, including quality control parameters

1 reference

12 December 2020

Determination of trovafloxacin, a new quinolone antibiotic, in biological samples by reversed-phase high-performance liquid chromatography

1 reference

12 December 2020

Fluoroquinolone antimicrobial agents

1 reference

12 December 2020

Synthesis of 18F-labeled fluconazole and positron emission tomography studies in rabbits

1 reference

12 December 2020

18F-labeling and biodistribution of the novel fluoro-quinolone antimicrobial agent, trovafloxacin (CP 99,219)

1 reference

12 December 2020

Synthesis and biodistribution of 18F-labeled fleroxacin

1 reference

12 December 2020

Identifiers

PMC publication ID

105732

1 reference

28 July 2017

1 reference