Engineering superior DNA vaccines: MHC class I single chain trimers bypass antigen processing and enhance the immune response to low affinity antigens (Q33698112)

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English	Engineering superior DNA vaccines: MHC class I single chain trimers bypass antigen processing and enhance the immune response to low affinity antigens	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

28 July 2017

Engineering superior DNA vaccines: MHC class I single chain trimers bypass antigen processing and enhance the immune response to low affinity antigens (English)

1 reference

Europe PubMed Central

28 July 2017

author name string

Lijin Li

1

1 reference

Europe PubMed Central

28 July 2017

John M Herndon

2

1 reference

Europe PubMed Central

28 July 2017

Steven M Truscott

3

1 reference

Europe PubMed Central

28 July 2017

Ted H Hansen

4

1 reference

Europe PubMed Central

28 July 2017

Timothy P Fleming

5

1 reference

Europe PubMed Central

28 July 2017

Peter Goedegebuure

6

1 reference

Europe PubMed Central

28 July 2017

William E Gillanders

7

1 reference

Europe PubMed Central

28 July 2017

language of work or name

0 references

publication date

1 February 2010

1 reference

Europe PubMed Central

28 July 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

28 July 2017

28

1 reference

Europe PubMed Central

28 July 2017

1911-1918

1 reference

Europe PubMed Central

28 July 2017

8

1 reference

Europe PubMed Central

28 July 2017

DNA vaccines: ready for prime time?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques

1 reference

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IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis

1 reference

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21 June 2018

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

1 reference

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21 June 2018

Human major histocompatibility complex (MHC) class I molecules with disulfide traps secure disease-related antigenic peptides and exclude competitor peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Structural Engineering of pMHC Reagents for T Cell Vaccines and Diagnostics

1 reference

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21 June 2018

Generation of mammaglobin-A-specific CD4 T cells and identification of candidate CD4 epitopes for breast cancer vaccine strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Disulfide bond engineering to trap peptides in the MHC class I binding groove

1 reference

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Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region

1 reference

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Transgenic expression of HLA-E single chain trimer protects porcine endothelial cells against human natural killer cell-mediated cytotoxicity

1 reference

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1 reference

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Hepatitis B virus core antigen epitopes presented by HLA-A2 single-chain trimers induce functional epitope-specific CD8+ T-cell responses in HLA-A2.1/Kb transgenic mice.

1 reference

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A DNA vaccine encoding a single-chain trimer of HLA-A2 linked to human mesothelin peptide generates anti-tumor effects against human mesothelin-expressing tumors

1 reference

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Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine

1 reference

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21 June 2018

Applications of major histocompatibility complex class I molecules expressed as single chains

1 reference

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21 June 2018

T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.

1 reference

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21 June 2018

T cell activation correlates with an increased proportion of antigen among the materials acquired from target cells

1 reference

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21 June 2018

Tat mammaglobin fusion protein transduced dendritic cells stimulate mammaglobin-specific CD4 and CD8 T cells

1 reference

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A new dynamic model of CD8+ T effector cell responses via CD4+ T helper-antigen-presenting cells

1 reference

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21 June 2018

Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

An HLA-E single chain trimer inhibits human NK cell reactivity towards porcine cells

1 reference

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Cancer immunotherapy using a DNA vaccine encoding a single-chain trimer of MHC class I linked to an HPV-16 E6 immunodominant CTL epitope

1 reference

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21 June 2018

Recognition of HLA-A2-restricted mammaglobin-A-derived epitopes by CD8+ cytotoxic T lymphocytes from breast cancer patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Mammaglobin-based strategies for treatment of breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Immune recognition of self in immunity against cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Helping the CD8(+) T-cell response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Tapasin enhances MHC class I peptide presentation according to peptide half-life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Generation of CD8+ cytotoxic T lymphocytes against breast cancer cells by stimulation with mammaglobin-A-pulsed dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Mammaglobin-A is a tumor-associated antigen in human breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Identification of HLA-A3-restricted CD8+ T cell epitopes derived from mammaglobin-A, a tumor-associated antigen of human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Cutting edge: single-chain trimers of MHC class I molecules form stable structures that potently stimulate antigen-specific T cells and B cells

1 reference

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CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes

1 reference

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21 June 2018

Mammaglobin, a breast-specific gene, and its utility as a marker for breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

DNA vaccines: immunology, application, and optimization*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Heteroclitic immunization induces tumor immunity

1 reference

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First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response

1 reference

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21 June 2018

Structure and transcriptional regulation of the human mammaglobin gene, a breast cancer associated member of the uteroglobin gene family localized to chromosome 11q13.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Comparison of various expression plasmids for the induction of immune response by DNA immunization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Induction of a CD8+ cytotoxic T lymphocyte response by cross-priming requires cognate CD4+ T cell help

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

21 June 2018

Gene inoculation generates immune responses against human immunodeficiency virus type 1

1 reference

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21 June 2018

Heterologous protection against influenza by injection of DNA encoding a viral protein

1 reference

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Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA.

1 reference

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DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody

1 reference

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DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations

1 reference

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Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides.

1 reference

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Generation, translocation, and presentation of MHC class I-restricted peptides

1 reference

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21 June 2018

Three-cell-type clusters of T cells with antigen-presenting cells best explain the epitope linkage and noncognate requirements of the in vivo cytolytic response

1 reference

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21 June 2018

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein

1 reference

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Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes

1 reference

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21 June 2018

Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes

1 reference

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21 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

30 October 2018

Processing of tumor-associated antigen by the proteasomes of dendritic cells controls in vivo T-cell responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

30 October 2018

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1 reference

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30 October 2018

Licensing of natural killer cells by host major histocompatibility complex class I molecules

1 reference

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30 October 2018

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1 reference

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30 October 2018

Enhanced immune presentation of a single-chain major histocompatibility complex class I molecule engineered to optimize linkage of a C-terminally extended peptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

30 October 2018

CD8 lethargy in the absence of CD4 help.

1 reference

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30 October 2018

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1 reference

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30 October 2018

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine.

1 reference

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30 October 2018

Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients.

1 reference

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30 October 2018

Genetic immunization is a simple method for eliciting an immune response

1 reference

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30 October 2018

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1 reference

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30 October 2018

CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2830906

30 October 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2009.10.096

7 January 2021

Immunodominance in TCD8+ responses to viruses: cell biology, cellular immunology, and mathematical models

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2009.10.096

7 January 2021

Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2009.10.096

7 January 2021

A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2009.10.096

7 January 2021

TCR binding kinetics measured with MHC class I tetramers reveal a positive selecting peptide with relatively high affinity for TCR

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2009.10.096

7 January 2021

Response of established human breast tumors to vaccination with mammaglobin-A cDNA

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2009.10.096

7 January 2021

Characterization of the role of CD8+T cells in breast cancer immunity following mammaglobin-A DNA vaccination using HLA-class-I tetramers

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2009.10.096

7 January 2021

Isolation of differentially expressed sequence tags from human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20188246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL

1 reference

https://pubmed.ncbi.nlm.nih.gov/20188246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammaglobin expression in primary, metastatic, and occult breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20188246

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.VACCINE.2009.10.096

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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