Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance (Q37286396)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15314692%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance (English)

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31 December 2019

9

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31 December 2019

8

Brian M Baker

1 reference

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31 December 2019

author name string

Zhiya Yu

1

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31 December 2019

Marc R Theoret

2

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31 December 2019

Christopher E Touloukian

3

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31 December 2019

Deborah R Surman

4

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31 December 2019

Scott C Garman

5

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31 December 2019

Lionel Feigenbaum

6

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31 December 2019

Tiffany K Baxter

7

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31 December 2019

language of work or name

English

0 references

publication date

1 August 2004

1 reference

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Journal of Clinical Investigation

31 December 2019

published in

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31 December 2019

volume

114

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31 December 2019

page(s)

551-559

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31 December 2019

issue

4

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Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

31 December 2019

cites work

1 reference

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Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma

6 September 2017

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Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens

6 September 2017

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Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes

6 September 2017

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Coordination of T cell activation and migration through formation of the immunological synapse.

6 September 2017

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Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy

6 September 2017

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Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

6 September 2017

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Tumor growth enhances cross-presentation leading to limited T cell activation without tolerance

6 September 2017

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Manipulation of avidity to improve effectiveness of adoptively transferred CD8(+) T cells for melanoma immunotherapy in human MHC class I-transgenic mice

6 September 2017

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A listing of human tumor antigens recognized by T cells

6 September 2017

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Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen

6 September 2017

1 reference

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Recombinant virus vaccination against "self" antigens using anchor-fixed immunogens

6 September 2017

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Immunizing patients with metastatic melanoma using recombinant adenoviruses encoding MART-1 or gp100 melanoma antigens

6 September 2017

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Heteroclitic immunization induces tumor immunity

6 September 2017

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gp100/pmel 17 is a murine tumor rejection antigen: induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand

6 September 2017

1 reference

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Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

6 September 2017

1 reference

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Models of T cell anergy: is there a common molecular mechanism?

6 September 2017

1 reference

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Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection

6 September 2017

1 reference

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Human CD8 transgene regulation of HLA recognition by murine T cells

6 September 2017

1 reference

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HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides

6 September 2017

1 reference

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Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer

6 September 2017

1 reference

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Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers.

28 September 2017

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High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy.

28 September 2017

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Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

28 September 2017

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Continuous T cell receptor signaling required for synapse maintenance and full effector potential

26 June 2018

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A single heteroclitic epitope determines cancer immunity after xenogeneic DNA immunization against a tumor differentiation antigen

3 September 2018

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Thermodynamic and Kinetic Analysis of a Peptide−Class I MHC Interaction Highlights the Noncovalent Nature and Conformational Dynamics of the Class I Heterotrimer

3 September 2018

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Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

3 September 2018

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Simian immunodeficiency virus evades a dominant epitope-specific cytotoxic T lymphocyte response through a mutation resulting in the accelerated dissociation of viral peptide and MHC class I.

3 September 2018

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The thymus and negative selection

3 September 2018

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12 December 2020

Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells

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12 December 2020

Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling

1 reference

12 December 2020

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor

1 reference

12 December 2020

Assembly and dissociation of human leukocyte antigen (HLA)-A2 studied by real-time fluorescence resonance energy transfer

1 reference

12 December 2020

Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex

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12 December 2020

Molecular mimicry and autoimmune disease

1 reference

12 December 2020

Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression

1 reference

12 December 2020

Cassette vectors directing expression of T cell receptor genes in transgenic mice

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12 December 2020

Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues

1 reference

12 December 2020

Fast Association Rates Suggest a Conformational Change in the MHC Class I Molecule H-2Dbupon Peptide Binding

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12 December 2020

Identifiers

DOI

10.1172/JCI200421695

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15314692%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15314692%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference