Thioredoxin reductase-1 mediates curcumin-induced radiosensitization of squamous carcinoma cells (Q33699108)

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18 January 2020

title

Thioredoxin reductase-1 mediates curcumin-induced radiosensitization of squamous carcinoma cells (English)

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18 January 2020

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8

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18 January 2020

6

Rosemarie Mick

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18 January 2020

author name string

Prashanthi Javvadi

1

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18 January 2020

Lauren Hertan

2

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18 January 2020

Rachelle Kosoff

3

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18 January 2020

Tatini Datta

4

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18 January 2020

Johann Kolev

5

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18 January 2020

Stephen W Tuttle

7

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18 January 2020

language of work or name

English

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publication date

16 February 2010

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18 January 2020

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18 January 2020

volume

70

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18 January 2020

issue

5

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18 January 2020

page(s)

1941-1950

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Decoding ARE-mediated decay: is microRNA part of the equation?

18 January 2020

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The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway

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Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals.

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On the potential of thioredoxin reductase inhibitors for cancer therapy

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Curcumin protects against radiation-induced acute and chronic cutaneous toxicity in mice and decreases mRNA expression of inflammatory and fibrogenic cytokines

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Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells

21 June 2018

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Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity

21 June 2018

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Curcumin: a new radio-sensitizer of squamous cell carcinoma cells.

21 June 2018

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Overexpression of enzymatically active human cytosolic and mitochondrial thioredoxin reductase in HEK-293 cells. Effect on cell growth and differentiation.

21 June 2018

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Thioredoxin reductase as a potential molecular target for anticancer agents that induce oxidative stress

21 June 2018

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Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2.

21 June 2018

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Tumor intracellular redox status and drug resistance--serendipity or a causal relationship?

21 June 2018

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Curcumin impairs tumor suppressor p53 function in colon cancer cells

21 June 2018

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Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3.

21 June 2018

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Overexpression of mitochondrial thioredoxin reductase and peroxiredoxin III in hepatocellular carcinomas

21 June 2018

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Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

21 June 2018

1 reference

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Radioprotective action of curcumin extracted from Curcuma longa LINN: inhibitory effect on formation of urinary 8-hydroxy-2'-deoxyguanosine, tumorigenesis, but not mortality, induced by gamma-ray irradiation

21 June 2018

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Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species

21 June 2018

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Multicenter phase Ib/II trial of the radiation enhancer motexafin gadolinium in patients with brain metastases

21 June 2018

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Thioredoxin reductase as a pathophysiological factor and drug target

21 June 2018

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A method for measuring disulfide reduction by cultured mammalian cells: relative contributions of glutathione-dependent and glutathione-independent mechanisms

21 June 2018

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21 June 2018

Thioredoxin reductase

1 reference

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Regulation of human thioredoxin reductase expression and activity by 3'-untranslated region selenocysteine insertion sequence and mRNA instability elements

21 June 2018

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Efficient reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase

21 June 2018

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A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity

21 June 2018

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Persistent oxidative stress in cancer

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Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors

21 June 2018

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Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives.

30 October 2018

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The thioredoxin-thioredoxin reductase system: over-expression in human cancer

30 October 2018

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Preliminary studies of the effects of gadolinium texaphyrin on the growth and radiosensitivity of EMT6 cells in vitro

30 October 2018

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Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation

30 October 2018

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Mechanisms of inhibition of the thioredoxin growth factor system by antitumor 2-imidazolyl disulfides

30 October 2018

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Redox-sensitive signaling factors and antioxidants: how tumor cells respond to ionizing radiation

30 October 2018

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12 December 2020

Protective effect of curcumin, ellagic acid and bixin on radiation induced toxicity

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12 December 2020

Modulation of radioresponse of glyoxalase system by curcumin

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12 December 2020

SYNTHESIS OF DIACETYLDICHLOROFLUORESCIN: A STABLE REAGENT FOR FLUOROMETRIC ANALYSIS

1 reference

12 December 2020

Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway

1 reference

12 December 2020

10.1158/0008-5472.CAN-09-3025

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20160040%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20160040%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

20160040

1 reference