Bcl-2 gene family and related proteins in mammary gland involution and breast cancer (Q33699417)

28 July 2017

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title

Bcl-2 gene family and related proteins in mammary gland involution and breast cancer (English)

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28 July 2017

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Schorr K

1

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28 July 2017

Li M

2

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28 July 2017

Krajewski S

3

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28 July 2017

Reed JC

4

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28 July 2017

Furth PA

5

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28 July 2017

publication date

1 April 1999

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Journal of Mammary Gland Biology and Neoplasia

28 July 2017

published in

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28 July 2017

volume

4

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28 July 2017

issue

2

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28 July 2017

page(s)

153-164

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

28 July 2017

cites work

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12 December 2020

Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.

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12 December 2020

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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12 December 2020

BCL-2 family: regulators of cell death

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12 December 2020

Diminished cell proliferation associated with the death-protective activity of Bcl-2

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12 December 2020

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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12 December 2020

Expression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors

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12 December 2020

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions

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12 December 2020

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

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12 December 2020

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

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12 December 2020

Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

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12 December 2020

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

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12 December 2020

bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice.

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12 December 2020

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

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12 December 2020

Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.

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12 December 2020

Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines

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12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

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12 December 2020

Testicular degeneration in Bclw-deficient mice

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12 December 2020

Developmental expression patterns of Bcl-2, Bcl-x, Bax, and Bak in teeth.

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12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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12 December 2020

Immunohistochemical analysis of in vivo patterns of Bcl-X expression

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12 December 2020

Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice

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12 December 2020

Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium

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12 December 2020

Deletion of a nonconserved region of Bcl-2 confers a novel gain of function: suppression of apoptosis with concomitant cell proliferation

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12 December 2020

A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.

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12 December 2020

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

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12 December 2020

Apoptosis and remodeling of mammary gland tissue during involution proceeds through p53-independent pathways

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12 December 2020

Mitochondria and apoptosis

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12 December 2020

Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

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12 December 2020

Expression and activity of cell cycle regulators during proliferation and programmed cell death in the mammary gland.

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12 December 2020

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

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12 December 2020

Physiological and induced neuronal death are not affected in NSE-bax transgenic mice

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12 December 2020

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

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12 December 2020

Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

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12 December 2020

Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice

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12 December 2020

Cre-mediated gene deletion in the mammary gland

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12 December 2020

Expression of a viral oncoprotein during mammary gland development alters cell fate and function: induction of p53-independent apoptosis is followed by impaired milk protein production in surviving cells.

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12 December 2020

Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7.

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12 December 2020

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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12 December 2020

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

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12 December 2020

The rise and fall of apoptosis during multistage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors

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12 December 2020

The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry

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12 December 2020

Bax and Bcl-xs are induced at the onset of apoptosis in involuting mammary epithelial cells

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12 December 2020

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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12 December 2020

Bcl-2 and the regulation of programmed cell death

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12 December 2020

Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types

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12 December 2020

Molecular regulation of apoptosis: genetic controls on cell death.

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12 December 2020

Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant

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12 December 2020

Widespread elimination of naturally occurring neuronal death in Bax-deficient mice

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12 December 2020

Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells

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12 December 2020

Ablation of bcl-2 gene expression decreases the numbers of oocytes and primordial follicles established in the post-natal female mouse gonad

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12 December 2020

Bcl-2 initiates a new category of oncogenes: regulators of cell death

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12 December 2020

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

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12 December 2020

bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine

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12 December 2020

Bcl-2 and Bax function independently to regulate cell death

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12 December 2020

Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development

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12 December 2020

Regulators of cell death

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12 December 2020

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

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12 December 2020

Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice.

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12 December 2020

Expression and location of pro-apoptotic Bcl-2 family protein BAD in normal human tissues and tumor cell lines.

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12 December 2020

Bclx regulates the survival of double-positive thymocytes

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12 December 2020

bcl-2 transgene expression can protect neurons against developmental and induced cell death

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12 December 2020

Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis

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12 December 2020

Apoptosis in the terminal endbud of the murine mammary gland: a mechanism of ductal morphogenesis.

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12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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12 December 2020

Checkpoints of dueling dimers foil death wishes

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12 December 2020

Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model

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12 December 2020

Role of Bag-1 in the survival and proliferation of the cytokine-dependent lymphocyte lines, Ba/F3 and Nb2.

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12 December 2020

Immunocytochemical localization of BCL-2 protein in human breast cancers and its relationship to a series of prognostic markers and response to endocrine therapy

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12 December 2020

The role of bcl-2 expression in breast carcinomas (Review).

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12 December 2020

Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death

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12 December 2020

Programmed cell death in the terminal endbud

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12 December 2020

Inactivation of Bcl-2 by phosphorylation

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12 December 2020

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

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12 December 2020

Double identity for proteins of the Bcl-2 family

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12 December 2020

Expression of death-related genes and their relationship to loss of apoptosis in T1 ductal breast carcinomas

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12 December 2020

BAX is required for neuronal death after trophic factor deprivation and during development

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12 December 2020

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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12 December 2020

Estrogen increases intracellular p26Bcl-2 to p21Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells

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12 December 2020

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

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12 December 2020

Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells

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12 December 2020

Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.

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12 December 2020

bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells

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12 December 2020

Balancing cell life and death: bax, apoptosis, and breast cancer

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12 December 2020

Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice.

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12 December 2020

Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

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12 December 2020

Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma

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12 December 2020

Gain of Bcl-2 is more potent than bax loss in regulating mammary epithelial cell survival in vivo

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12 December 2020

Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.

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12 December 2020

Apoptosis suppressing protein bcl-2 is expressed in well-differentiated breast carcinomas with favourable prognosis

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12 December 2020

The Bcl-2 protein family: arbiters of cell survival

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12 December 2020

Identifiers

DOI

10.1023/A:1018773123899

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Dimensions Publication ID

28 July 2017

1021959257

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