Sensitivity to the aromatase inhibitor letrozole is prolonged after a "break" in treatment (Q33700933)

28 July 2017

Sensitivity to the aromatase inhibitor letrozole is prolonged after a "break" in treatment (English)

1 reference

28 July 2017

Gauri Sabnis

1

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author name string

Olga Goloubeva

2

1 reference

28 July 2017

Rabia Gilani

3

1 reference

28 July 2017

Luciana Macedo

4

1 reference

28 July 2017

Angela Brodie

5

1 reference

28 July 2017

6 January 2010

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Molecular Cancer Therapeutics

28 July 2017

1 reference

28 July 2017

9

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28 July 2017

46-56

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28 July 2017

1

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describes a project that uses

28 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2831468/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

History of aromatase: saga of an important biological mediator and therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen

21 June 2018

1 reference

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Extended adjuvant endocrine therapy in breast cancer: current status and future directions

21 June 2018

1 reference

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Stopping treatment can reverse acquired resistance to letrozole

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy resistance

21 June 2018

1 reference

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Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer

21 June 2018

1 reference

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P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Additive antitumor effect of aromatase inhibitor letrozole and antiestrogen fulvestrant in a postmenopausal breast cancer model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Activation of mitogen-activated protein kinase in xenografts and cells during prolonged treatment with aromatase inhibitor letrozole

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

The role of growth factor receptor pathways in human breast cancer cells adapted to long-term estrogen deprivation

21 June 2018

1 reference

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Reversal of tamoxifen resistant breast cancer by low dose estrogen therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

HER-2 gene amplification can be acquired as breast cancer progresses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

The intratumoral aromatase model: studies with aromatase inhibitors and antiestrogens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Adaptive hypersensitivity following long-term estrogen deprivation: involvement of multiple signal pathways

21 June 2018

1 reference

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Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: long-term studies using the intratumoral aromatase postmenopausal breast cancer model.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Antitumor action of physiological estradiol on tamoxifen-stimulated breast tumors grown in athymic mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Stable expression of human aromatase complementary DNA in mammalian cells: a useful system for aromatase inhibitor screening

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Aromatase inhibitors--a triumph of translational oncology

21 June 2018

1 reference

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Serum HER-2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

Therapeutic strategies using the aromatase inhibitor letrozole and tamoxifen in a breast cancer model

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831468

MCF-7 human breast carcinomas in nude mice as a model for evaluating aromatase inhibitors

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20053764

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A new nude mouse model for postmenopausal breast cancer using MCF-7 cells transfected with the human aromatase gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20053764

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1535-7163.MCT-09-0696

1 reference

28 July 2017

1 reference

28 July 2017

1 reference