The arachidonate 12/15 lipoxygenases. A review of tissue expression and biologic function (Q33705477)

28 July 2017

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title

The arachidonate 12/15 lipoxygenases. A review of tissue expression and biologic function (English)

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28 July 2017

Conrad DJ

1

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28 July 2017

1 March 1999

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Clinical Reviews in Allergy & Immunology

28 July 2017

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28 July 2017

17

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28 July 2017

71-89

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28 July 2017

1-2

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https://scigraph.springernature.com/pub.10.1007/bf02737598

28 July 2017

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cites work

Arachidonic acid 15-lipoxygenase and airway epithelium. Biologic effects and enzyme purification

1 reference

https://api.crossref.org/works/10.1007%2FBF02737598

Regulation of 15-lipoxygenase expression in lung epithelial cells by interleukin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02737598

Characterization and sequence of an additional 15-lipoxygenase transcript and of the human gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02737598

Calcium promotes membrane association of reticulocyte 15-lipoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02737598

Lipoxin biosynthesis and its impact in inflammatory and vascular events

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02737598

Inhibition of stimulus-induced endothelial cell intercellular adhesion molecule-1, E-selectin, and vascular cellular adhesion molecule-1 expression by arachidonic acid and its hydroxy and hydroperoxy derivatives

21 January 2018

1 reference

12 December 2020

Oxygenation of biomembranes by mammalian lipoxygenases: the role of ubiquinone.

1 reference

12 December 2020

Loss of cytosolic 15-lipoxygenase activity in A23187-stimulated human leukocytes: involvement of a translocation process?

1 reference

12 December 2020

15-Hydroxyeicosatetraenoic acid inhibits neutrophil migration across cytokine-activated endothelium

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12 December 2020

The action of lipoxin-A on glomerular microcirculatory dynamics in the rat

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12 December 2020

Structure conservation in lipoxygenases: structural analysis of soybean lipoxygenase-1 and modeling of human lipoxygenases.

1 reference

12 December 2020

Self-inactivation by 13-hydroperoxylinoleic acid and lipohydroperoxidase activity of the reticulocyte lipoxygenase

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12 December 2020

15-Lipoxygenase expression in smooth muscle cells from atherosclerotic rabbit aortas

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12 December 2020

Structure of the mRNA and of the gene coding for the rabbit erythroid 15-lipoxygenase.

1 reference

12 December 2020

Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein

1 reference

12 December 2020

Oxygenation of lipoproteins by mammalian lipoxygenases.

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12 December 2020

Enzymatic properties of the 15-lipoxygenase of human cultured keratinocytes

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12 December 2020

15-Lipoxygenase products stimulate prolactin secretion from a cloned strain of rat pituitary cells

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12 December 2020

Human 15-lipoxygenase: induction by interleukin-4 and insights into positional specificity

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12 December 2020

The complete sequence of the rabbit erythroid cell-specific 15-lipoxygenase mRNA: comparison of the predicted amino acid sequence of the erythrocyte lipoxygenase with other lipoxygenases

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12 December 2020

Occurrence of lipoxygenase products in membranes of rabbit reticulocytes. Evidence for a role of the reticulocyte lipoxygenase in the maturation of red cells

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12 December 2020

Melanoma cell spreading on fibronectin induced by 12(S)-HETE involves both protein kinase C- and protein tyrosine kinase-dependent focal adhesion formation and tyrosine phosphorylation of focal adhesion kinase (pp125FAK)

1 reference

12 December 2020

mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end.

1 reference

12 December 2020

Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4

1 reference

12 December 2020

Translation of 15-lipoxygenase mRNA is inhibited by a protein that binds to a repeated sequence in the 3' untranslated region

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12 December 2020

Oxygenation of biological membranes by the pure reticulocyte lipoxygenase.

1 reference

12 December 2020

An in vivo chemotaxis assay in the dog trachea: evidence for chemotactic activity of 8,15-diHETE.

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12 December 2020

Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins

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12 December 2020

Lipoxygenase mRNA in cultured human epidermal and oral keratinocytes.

1 reference

12 December 2020

Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases

1 reference

12 December 2020

The expression of 15-lipoxygenase gene and the presence of functional enzyme in cytoplasm and nuclei of pregnancy human myometria

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12 December 2020

Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea

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12 December 2020

Occurrence of the erythroid cell specific arachidonate 15-lipoxygenase in human reticulocytes

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12 December 2020

Activation of protein kinase C by lipoxin A and other eicosanoids. Intracellular action of oxygenation products of arachidonic acid

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12 December 2020

Lipoxygenase-generated icosanoids inhibit glucose-induced insulin release from rat islets

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12 December 2020

Attenuation of diet-induced atherosclerosis in rabbits with a highly selective 15-lipoxygenase inhibitor lacking significant antioxidant properties

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12 December 2020

Activation of microvascular endothelium by eicosanoid 12(S)-hydroxyeicosatetraenoic acid leads to enhanced tumor cell adhesion via up-regulation of surface expression of alpha v beta 3 integrin: a posttranscriptional, protein kinase C- and cytoskele

1 reference

12 December 2020

Modulation of Fcγ receptors on T cells and monocytes by 15 hydroperoxyeicosatetranoic acid

1 reference

12 December 2020

Characterization of a 15-lipoxygenase in human breast carcinoma BT-20 cells: stimulation of 13-HODE formation by TGF alpha/EGF.

1 reference

12 December 2020

Arachidonate lipoxygenase metabolite formation in gestational tissues

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12 December 2020

Regulation of leukocyte and platelet lipoxygenases by hydroxyeicosanoids

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12 December 2020

Action of novel eicosanoids lipoxin A and B on human natural killer cell cytotoxicity: effects on intracellular cAMP and target cell binding

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12 December 2020

Multiple use of a signal transduction pathway in tumor cell invasion

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12 December 2020

Role of the lipoxygenase pathway in angiotensin II-induced vascular smooth muscle cell hypertrophy.

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12 December 2020

Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts

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12 December 2020

Interleukin-1 increases 15-hydroxyeicosatetraenoic acid formation in cultured human endothelial cells

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12 December 2020

Transcellular biosynthesis of lipoxin A4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis

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12 December 2020

Inhibition of leukotriene B4-induced neutrophil migration by lipoxin A4: structure-function relationships

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12 December 2020

Enzymology and physiology of reticulocyte lipoxygenase: comparison with other lipoxygenases

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12 December 2020

Leukotriene B4 induces airway hyperresponsiveness in dogs.

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12 December 2020

Biosynthesis and metabolism of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid by human umbilical vein endothelial cells

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12 December 2020

The Lipoxygenase of Reticulocytes. Purification, Characterization and Biological Dynamics of the Lipoxygenase; Its Identity with the Respiratory Inhibitors of the Reticulocyte

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12 December 2020

A function for lipoxygenase in programmed organelle degradation

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12 December 2020

Tissue-specific regulation of the rabbit 15-lipoxygenase gene in erythroid cells by a transcriptional silencer

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12 December 2020

Human airway monohydroxyeicosatetraenoic acid generation and mucus release

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12 December 2020

Formation of monohydroxyeicosatetraenoic acids from arachidonic acid by cultured rabbit aortic smooth muscle cells

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12 December 2020

The inhibitory role of 12- and 15-lipoxygenase products on renin release

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12 December 2020

Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development

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12 December 2020

Identification of 5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid as a novel and potent human eosinophil chemotactic eicosanoid

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12 December 2020

Regional synthesis of monohydroxy eicosanoids by the kidney

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12 December 2020

Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes

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12 December 2020

Leukotrienes and lipoxins: structures, biosynthesis, and biological effects

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12 December 2020

Cloning of human airway 15-lipoxygenase: identity to the reticulocyte enzyme and expression in epithelium

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12 December 2020

15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase

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12 December 2020

Identification of a specific methionine in mammalian 15-lipoxygenase which is oxygenated by the enzyme product 13-HPODE: dissociation of sulfoxide formation from self-inactivation

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12 December 2020

Involvement of 15-lipoxygenase in early stages of atherogenesis

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12 December 2020

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

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12 December 2020

Conversion of leukotriene A4 to lipoxins by human nasal polyps and bronchial tissue

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12 December 2020

Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation

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12 December 2020

Immunohistochemical demonstration of 15-lipoxygenase in transplant coronary artery disease

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12 December 2020

Transformation of arachidonic acid by 5- and 15-lipoxygenase pathways in bovine adrenal fasciculata cells

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12 December 2020

Identification of lipoxin A4 and its relationship to the sulfidopeptide leukotrienes C4, D4, and E4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary diseases

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12 December 2020

Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase

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12 December 2020

Identification of a novel and highly potent eosinophil chemotactic lipid in human eosinophils treated with arachidonic acid

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12 December 2020

Activation of mitogen-activated protein kinases by arachidonic acid and its metabolites in vascular smooth muscle cells

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12 December 2020

Structural and functional evidence for activation of a chick retinoid X receptor by eicosanoids

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12 December 2020

15-lipoxygenase metabolite(s) of arachidonic acid mediates adrenocorticotropin action in bovine adrenal steroidogenesis

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12 December 2020

The actions of 5-, 12-, and 15-HETE on tracheobronchial smooth muscle

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12 December 2020

Arachidonic acid metabolism in normal and hypereosinophilic syndrome human eosinophils: generation of leukotrienes B4, C4, D4 and 15-lipoxygenase products

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12 December 2020

Lipoxin formation in human nasal polyps and bronchial tissue

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12 December 2020

Chemokinetic activity of arachidonic acid lipoxygenase products on leuocyctes of different species

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12 December 2020

Substitution of 15-hydroxyeicosatetraenoic acid in the phosphoinositide signaling pathway.

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12 December 2020

15-Hydroperoxyeicosatetraenoic acid inhibits human platelet aggregation

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12 December 2020

Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers

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12 December 2020

Inhibition of phytohemagglutinin-induced lymphocyte mitogenesis by lipoxygenase metabolites of arachidonic acid: structure-activity relationships

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12 December 2020

On the optimal conditions of LTC4 formation by human eosinophils in vitro

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12 December 2020

Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acid

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12 December 2020

Arachidonic acid 15-lipoxygenase products from human eosinophils

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12 December 2020

Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocytes, leukocytes, and airway cells

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12 December 2020

Role of lipoxygenase in the mechanism of acrosome reaction in mammalian spermatozoa

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12 December 2020

Lipoxygenase products in normal and diseased glomeruli

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12 December 2020

Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells

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12 December 2020

The linoleic acid metabolite, (13S)-hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in Syrian hamster embryo tumor suppressor phenot

1 reference

12 December 2020

15-Lipoxygenase products of arachidonate play a role in proliferation of transformed erythroid cells

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12 December 2020

Co-regulated expression of glomerular 12/15-lipoxygenase and interleukin-4 mRNAs in rat nephrotoxic nephritis.

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12 December 2020

Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors

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12 December 2020

Effects of arachidonic acid hydroperoxides on vascular and non-vascular smooth muscle

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12 December 2020

Selective generation of leukotriene B4 by tracheal epithelial cells from dogs

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12 December 2020

Enhanced levels of lipoperoxides in low density lipoprotein incubated with murine fibroblast expressing high levels of human 15-lipoxygenase

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12 December 2020

15-lipoxygenase immunoreactivity in normal and in asthmatic airways

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12 December 2020

The promoter structure and complete sequence of the gene encoding the rabbit erythroid cell-specific 15-lipoxygenase

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12 December 2020

The effects of lipoxin A4 on airway responses in asthmatic subjects

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12 December 2020

Angiotensin II increases macrophage-mediated modification of low density lipoprotein via a lipoxygenase-dependent pathway

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12 December 2020

Histochemical evidence for induction of arachidonate 15-lipoxygenase in airway disease

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12 December 2020

Effects of 15-hydroperoxyeicosatetraenoic acid on human lymphocyte sheep erythrocyte rosette formation and response to concanavalin A associated with HLA system

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12 December 2020

Hydroperoxyeicosatetraenoic acids. Potent inhibitors of lymphocyte responses

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12 December 2020

A novel dioxygenation product of arachidonic acid possesses potent chemotactic activity for human polymorphonuclear leukocytes

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12 December 2020

Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes

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12 December 2020

Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein

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12 December 2020

Regulation of T-lymphocyte mitogenesis by the leukocyte product 15-hydroxy-eicosatetraenoic acid (15-HETE)

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12 December 2020

Methionine sulfoxide formation: the cause of self-inactivation of reticulocyte lipoxygenase

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12 December 2020

Expression of cloned human reticulocyte 15-lipoxygenase and immunological evidence that 15-lipoxygenases of different cell types are related

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12 December 2020

Autocrine motility factor signals integrin-mediated metastatic melanoma cell adhesion and invasion

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12 December 2020

Metabolism of arachidonic acid by human nasal and bronchial epithelial cells

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12 December 2020

Effects on glucose-induced insulin secretion of lipoxygenase-derived metabolites of arachidonic acid

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12 December 2020

Modulation of the beta-adrenergic response of cardiomyocytes by specific lipoxygenase products involves their incorporation into phosphatidylinositol and activation of protein kinase C

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12 December 2020

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions

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12 December 2020

Metabolism of arachidonic acid via the lipoxygenase pathway in human and murine glomeruli

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12 December 2020

Altered responses of human macrophages to lipopolysaccharide by hydroperoxy eicosatetraenoic acid, hydroxy eicosatetraenoic acid, and arachidonic acid. Inhibition of tumor necrosis factor production

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12 December 2020

Inhibition of human natural killer cell activity by (14R,15S)-14,15-dihydroxy-5Z,8Z,10E,12E- icosatetraenoic acid

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12 December 2020

Eosinophil 15-lipoxygenase is a leukotriene A4 synthase.

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12 December 2020

Eicosanoid mediator expression in mononuclear and polymorphonuclear cells in normal subjects and patients with atopic asthma and cystic fibrosis

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12 December 2020

Release of prostaglandin D2 into human airways during acute antigen challenge

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12 December 2020

15-Lipoxygenase products as leukotriene antagonists: therapeutic potential in glomerulonephritis

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12 December 2020

On singular or dual positional specificity of lipoxygenases. The number of chiral products varies with alignment of methylene groups at the active site of the enzyme

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12 December 2020

The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: structure-activity relationship and mechanism of action

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12 December 2020

Cyclo-oxygenase blockers influence the effects of 15-lipoxygenase metabolites of arachidonic acid in isolated canine blood vessels

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12 December 2020

Modulation of insulin secretion by lipoxygenase products of arachidonic acid. Relation to lipoxygenase activity of pancreatic islets

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12 December 2020

Discovery of a second 15S-lipoxygenase in humans

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12 December 2020

In vivo action of 15-lipoxygenase in early stages of human atherogenesis

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12 December 2020

Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor

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12 December 2020

Human 15-lipoxygenase: a potential effector molecule for interleukin-4.

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12 December 2020

Inhibitory effects of arachidonic acid (20:4,n-6) and its monohydroperoxy- and hydroxy-metabolites on procoagulant activity in endothelial cells

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12 December 2020

Identifiers

DOI

10.1007/BF02737598

1 reference

PubMed ID

10436860

Dimensions Publication ID

28 July 2017

0 references

1 reference

PubMed ID

10436860