New perspectives for the development of selective metabotropic glutamate receptor ligands. (Q33709295)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

review article

1 reference

title

New perspectives for the development of selective metabotropic glutamate receptor ligands (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

author name string

C De Colle

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

A S Bessis

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

F Acher

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

language of work or name

English

0 references

publication date

1 June 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Pharmacology

11 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

volume

375

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

issue

1-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

page(s)

277-294

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes

11 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

(S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Rapid agonist mediated phosphorylation of the metabotropic glutamate receptor 1 alpha by protein kinase C in permanently transfected BHK cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Structure of a glutamate-receptor ligand-binding core in complex with kainate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Extended glutamate activates metabotropic receptor types 1, 2 and 4: selective features at mGluR4 binding site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Extreme C terminus of G protein alpha-subunits contains a site that discriminates between Gi-coupled metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Molecular tinkering of G protein-coupled receptors: an evolutionary success

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Neuroprotective effects of a systemically active group II metabotropic glutamate receptor agonist LY354740 in a gerbil model of global ischaemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

How receptors talk to trimeric G proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Comparative effect of L-CCG-I, DCG-IV and gamma-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Homer: a protein that selectively binds metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Pharmacology of (S)-homoquisqualic acid and (S)-2-amino-5-phosphonopentanoic acid [(S)-AP5] at cloned metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

New analogues of ACPD with selective activity for group II metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Molecular pharmacology of homologues of ibotenic acid at cloned metabotropic glutamic acid receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Pharmacology and functions of metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Direct effects of metabotropic glutamate receptor compounds on native and recombinant N-methyl-D-aspartate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Cloning and characterization of alternative mRNA forms for the rat metabotropic glutamate receptors mGluR7 and mGluR8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Homology modeling of metabotropic glutamate receptors. (mGluRs) structural motifs affecting binding modes and pharmacological profile of mGluR1 agonists and competitive antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Definition of a pharmacophore for the metabotropic glutamate receptors negatively linked to adenylyl cyclase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

(2S,4S)-amino-4-(2,2-diphenylethyl)pentanedioic acid selective group 2 metabotropic glutamate receptor antagonist.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Activation of a Large-conductance Ca2+-Dependent K+ Channel by Stimulation of Glutamate Phosphoinositide-coupled Receptors in Cultured Cerebellar Granule Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Mutational analysis of the cysteines in the extracellular domain of the human Ca2+ receptor: effects on cell surface expression, dimerization and signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Glutamate mediates an inhibitory postsynaptic potential in dopamine neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

A novel splice variant of a metabotropic glutamate receptor, human mGluR7b

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Role of the second and third intracellular loops of metabotropic glutamate receptors in mediating dual signal transduction activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

LY354740: a metabotropic glutamate receptor agonist which ameliorates symptoms of nicotine withdrawal in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Reversible and non-competitive antagonist profile of CPCCOEt at the human type 1alpha metabotropic glutamate receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Functional switch from facilitation to inhibition in the control of glutamate release by metabotropic glutamate receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Novel members of the Vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

LY354740, a group II metabotropic glutamate receptor agonist with potential antiparkinsonian properties in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Structural basis for a Ca2+-sensing function of the metabotropic glutamate receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Role of heteromer formation in GABAB receptor function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Glutamate receptors of the kainate type and synaptic transmission

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Pharmacology of metabotropic glutamate receptors at the mossy fiber synapses of the guinea pig hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

A cluster of basic residues in the carboxyl-terminal tail of the short metabotropic glutamate receptor 1 variants impairs their coupling to phospholipase C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Phosphorylation and calmodulin binding of the metabotropic glutamate receptor subtype 5 (mGluR5) are antagonistic in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Calcimimetics with potent and selective activity on the parathyroid calcium receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Expression and purification of the extracellular ligand binding region of metabotropic glutamate receptor subtype 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

[3H]LY341495, a highly potent, selective and novel radioligand for labeling Group II metabotropic glutamate receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Cloning and functional expression of a Drosophila metabotropic glutamate receptor expressed in the embryonic CNS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

(S)-(+)-2-(3'-carboxybicyclo[1.1.1]pentyl)-glycine, a structurally new group I metabotropic glutamate receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Synthesis and preliminary evaluation of (S)-2-(4'-carboxycubyl)glycine, a new selective mGluR1 antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

The Ca2+/C1- dependent L-[3H]glutamate binding: a new receptor or a particular transport process?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Atomic structures of periplasmic binding proteins and the high-affinity active transport systems in bacteria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Metabotropic glutamate receptor 5 is a disulfide-linked dimer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

A modulatory effect of extracellular Ca2+ on type 1alpha metabotropic glutamate receptor-mediated signalling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

In vitro binding characteristics of a new selective group II metabotropic glutamate receptor radioligand, [3H]LY354740, in rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Axon/dendrite targeting of metabotropic glutamate receptors by their cytoplasmic carboxy-terminal domains.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Aminobicyclo[2.2.1.]heptane dicarboxylic acids (ABHD), rigid analogs of ACPD and glutamic acid: synthesis and pharmacological activity on metabotropic receptors mGluR1 and mGluR2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

The agonist selectivity of a class III metabotropic glutamate receptor, human mGluR4a, is determined by the N-terminal extracellular domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Synthesis and metabotropic glutamate receptor antagonist activity of N1-substituted analogs of 2R,4R-4-aminopyrrolidine-2,4-dicarboxylic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

(2S,4S)-2-amino-4-(4,4-diphenylbut-1-yl)- pentane-1,5-dioic acid: a potent and selective antagonist for metabotropic glutamate receptors negatively linked to adenylate cyclase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Heterodimerization is required for the formation of a functional GABA(B) receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2899%2900258-7

10.1016/S0014-2999(99)00258-7

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443583%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

1 reference