Platelet factor 4 is produced by subsets of myeloid cells in premetastatic lung and inhibits tumor metastasis (Q33709419)

28 July 2017

title

Platelet factor 4 is produced by subsets of myeloid cells in premetastatic lung and inhibits tumor metastasis (English)

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28 July 2017

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Jiang Jian

1

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28 July 2017

Yanli Pang

2

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28 July 2017

H Hannah Yan

3

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28 July 2017

Yongfen Min

4

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28 July 2017

Bhagelu R Achyut

5

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28 July 2017

M Christine Hollander

6

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28 July 2017

P Charles Lin

7

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28 July 2017

Xinhua Liang

8

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28 July 2017

Li Yang

9

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28 July 2017

language of work or name

English

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publication date

19 May 2016

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28 July 2017

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28 July 2017

volume

8

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28 July 2017

issue

17

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28 July 2017

page(s)

27725-27739

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CXCR3 as a molecular target in breast cancer metastasis: inhibition of tumor cell migration and promotion of host anti-tumor immunity.

28 July 2017

cites work

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21 June 2018

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21 June 2018

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Angiostatic, tumor inflammatory and anti-tumor effects of CXCL4(47-70) and CXCL4L1(47-70) in an EGF-dependent breast cancer model

21 June 2018

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Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.

21 June 2018

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Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells.

21 June 2018

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Platelet factor 4 inhibits IL-17/Stat3 pathway via upregulation of SOCS3 expression in melanoma

21 June 2018

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Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis

21 June 2018

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TGF-β signaling in myeloid cells is required for tumor metastasis

21 June 2018

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Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1.

21 June 2018

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Platelet factor-4 (CXCL4/PF-4): an angiostatic chemokine for cancer therapy.

21 June 2018

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Lineage tracing of Pf4-Cre marks hematopoietic stem cells and their progeny

21 June 2018

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Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12.

21 June 2018

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Platelet factor 4 induces cell apoptosis by inhibition of STAT3 via up-regulation of SOCS3 expression in multiple myeloma

21 June 2018

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Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

21 June 2018

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The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.

21 June 2018

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The role of the CXC chemokines platelet factor-4 (CXCL4/PF-4) and its variant (CXCL4L1/PF-4var) in inflammation, angiogenesis and cancer

21 June 2018

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Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3.

21 June 2018

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Elevated expression of CXC chemokines in pediatric osteosarcoma patients

21 June 2018

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Recombinant platelet factor 4: a therapeutic, anti-neoplastic chimera?

21 June 2018

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Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung

21 June 2018

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Role of the platelet chemokine platelet factor 4 (PF4) in hemostasis and thrombosis

21 June 2018

1 reference

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Platelet factor 4 is highly upregulated in dendritic cells after severe trauma

21 June 2018

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Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN

21 June 2018

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The metastatic niche: adapting the foreign soil

21 June 2018

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Trophic macrophages in development and disease

21 June 2018

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Microenvironmental regulation of metastasis

21 June 2018

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Myeloid-derived suppressor cells as regulators of the immune system

21 June 2018

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Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

21 June 2018

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TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

21 June 2018

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Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis

21 June 2018

1 reference

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Platelet factor-4 variant chemokine CXCL4L1 inhibits melanoma and lung carcinoma growth and metastasis by preventing angiogenesis.

21 June 2018

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Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

21 June 2018

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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438604

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438604

21 June 2018

Inflammation and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438604

Cell dissociation techniques in human breast cancer--variations in tumor cell viability and DNA ploidy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438604

Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438604

CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438604

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438604

30 October 2018

1 reference

12 December 2020

TGF-β signalling-related markers in cancer patients with bone metastasis

1 reference

12 December 2020

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

1 reference

12 December 2020

Serum protein signature may improve detection of ductal carcinoma in situ of the breast

1 reference

12 December 2020

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

1 reference

12 December 2020

Regulated expression of platelet factor 4 in human monocytes--role of PARs as a quantitatively important monocyte activation pathway

1 reference

12 December 2020

VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients

1 reference

12 December 2020

Differential changes in platelet VEGF, Tsp, CXCL12, and CXCL4 in patients with metastatic cancer

1 reference

12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.9486

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28 July 2017

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28 July 2017

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