Intravenous levetiracetam in the rat pilocarpine-induced status epilepticus model: behavioral, physiological and histological studies (Q33709815)

28 July 2017

title

Intravenous levetiracetam in the rat pilocarpine-induced status epilepticus model: behavioral, physiological and histological studies (English)

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28 July 2017

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3

Sydney S Cash

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28 July 2017

Yi Zheng

1

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28 July 2017

Jon Moussally

series ordinal

2

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28 July 2017

Havisha B Karnam

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4

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28 July 2017

Andrew J Cole

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5

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28 July 2017

publication date

21 December 2009

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28 July 2017

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28 July 2017

volume

58

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28 July 2017

issue

4-5

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28 July 2017

page(s)

793-798

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The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam

28 July 2017

cites work

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Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs

21 June 2018

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21 June 2018

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Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

21 June 2018

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Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy

21 June 2018

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21 June 2018

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21 June 2018

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Profile of ucb L059, a novel anticonvulsant drug, in models of partial and generalized epilepsy in mice and rats

21 June 2018

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Response of status epilepticus induced by lithium and pilocarpine to treatment with diazepam

21 June 2018

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Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy

21 June 2018

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A progressive sequence of electroencephalographic changes during generalized convulsive status epilepticus

21 June 2018

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21 June 2018

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Levetiracetam: antiepileptic properties and protective effects on mitochondrial dysfunction in experimental status epilepticus

21 June 2018

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Rapid kindling in preclinical anti-epileptic drug development: the effect of levetiracetam

30 October 2018

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Separation of antiepileptogenic and antiseizure effects of levetiracetam in the spontaneously epileptic rat (SER).

30 October 2018

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Evaluation of levetiracetam effects on pilocarpine-induced seizures: cholinergic muscarinic system involvement

30 October 2018

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Levetiracetam prevents changes in levels of brain-derived neurotrophic factor and neuropeptide Y mRNA and of Y1- and Y5-like receptors in the hippocampus of rats undergoing amygdala kindling: implications for antiepileptogenic and mood-stabilizing p

30 October 2018

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Anticonvulsant effects of levetiracetam and levetiracetam-diazepam combinations in experimental status epilepticus

30 October 2018

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Absence of negative impact of levetiracetam on cognitive function and memory in normal and amygdala-kindled rats.

30 October 2018

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Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy

30 October 2018

1 reference

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Refractory status epilepticus: frequency, risk factors, and impact on outcome

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834228

Levetiracetam does not modulate neuronal voltage-gated Na+ and T-type Ca2+ currents

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834228

Levetiracetam inhibits the high-voltage-activated Ca(2+) current in pyramidal neurones of rat hippocampal slices

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834228

NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.

30 October 2018

1 reference

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Blood and cerebrospinal fluid pharmacokinetics of the novel anticonvulsant levetiracetam (ucb L059) in the rat.

30 October 2018

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Neuronal stress and injury in C57/BL mice after systemic kainic acid administration

30 October 2018

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A prospective, population-based epidemiologic study of status epilepticus in Richmond, Virginia

30 October 2018

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Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures.

30 October 2018

1 reference

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Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb L059) in the kindling model of temporal lobe epilepsy

30 October 2018

1 reference

12 December 2020

Treatment options for status epilepticus

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12 December 2020

Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy

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12 December 2020

A new method to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA

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12 December 2020

Effects of valproate, vigabatrin and tiagabine on GABA uptake into human astrocytes cultured from foetal and adult brain tissue

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12 December 2020

Multicenter double-blind, randomized, placebo-controlled trial of levetiracetam as add-on therapy in patients with refractory partial seizures. European Levetiracetam Study Group

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12 December 2020

Administration of levetiracetam after prolonged status epilepticus does not protect from mitochondrial dysfunction in a rodent model

1 reference

12 December 2020

10.1016/J.NEUROPHARM.2009.12.007

Identifiers

DOI

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28 July 2017

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28 July 2017

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