Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development. (Q33714250)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215353%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development (English)

1 reference

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19 January 2020

9

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19 January 2020

author name string

Sunny Hartwig

1

1 reference

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19 January 2020

Jacqueline Ho

2

1 reference

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19 January 2020

Priyanka Pandey

3

1 reference

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19 January 2020

Kenzie Macisaac

4

1 reference

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19 January 2020

Mary Taglienti

5

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19 January 2020

Michael Xiang

6

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19 January 2020

Gil Alterovitz

7

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19 January 2020

Marco Ramoni

8

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19 January 2020

Jordan A Kreidberg

10

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19 January 2020

language of work or name

English

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publication date

1 April 2010

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19 January 2020

number of pages

15

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inferred from page(s)

published in

Development

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19 January 2020

volume

137

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19 January 2020

issue

7

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19 January 2020

page(s)

1189-1203

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Insights from genomic profiling of transcription factors

19 January 2020

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P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons

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21 June 2018

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21 June 2018

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21 June 2018

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Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo

21 June 2018

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21 June 2018

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Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

21 June 2018

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Hhat is a palmitoylacyltransferase with specificity for N-palmitoylation of Sonic Hedgehog

21 June 2018

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Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11

21 June 2018

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Neph1, a component of the kidney slit diaphragm, is tyrosine-phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2.

21 June 2018

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Distinct roles and regulations for HoxD genes in metanephric kidney development

21 June 2018

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Genomic analysis of gastrulation and organogenesis in the mouse

21 June 2018

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FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway

21 June 2018

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21 June 2018

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SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation

21 June 2018

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21 June 2018

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Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning

21 June 2018

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21 June 2018

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Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects

21 June 2018

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21 June 2018

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The establishment of neuronal properties is controlled by Sox4 and Sox11

21 June 2018

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Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney

21 June 2018

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21 June 2018

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Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival

21 June 2018

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Analysing the developing brain transcriptome with the GenePaint platform

21 June 2018

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The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron

21 June 2018

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Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression

21 June 2018

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Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme

21 June 2018

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A hypothesis-based approach for identifying the binding specificity of regulatory proteins from chromatin immunoprecipitation data.

21 June 2018

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Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa

21 June 2018

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Core transcriptional regulatory circuitry in human embryonic stem cells

21 June 2018

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Nab proteins are essential for peripheral nervous system myelination

21 June 2018

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Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway

21 June 2018

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Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia

21 June 2018

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Glypican-3 modulates inhibitory Bmp2-Smad signaling to control renal development in vivo

21 June 2018

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Role of the basic helix-loop-helix transcription factor, scleraxis, in the regulation of Sertoli cell function and differentiation

21 June 2018

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A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system

21 June 2018

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LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration

21 June 2018

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Role of fibroblast growth factor receptors 1 and 2 in the ureteric bud.

21 June 2018

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Interaction between the internal motif KTXXXI of Idax and mDvl PDZ domain

21 June 2018

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Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling

21 June 2018

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FGF acts directly on the somitic tendon progenitors through the Ets transcription factors Pea3 and Erm to regulate scleraxis expression

21 June 2018

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Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2

21 June 2018

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Congenital diaphragmatic hernia, kidney agenesis and cardiac defects associated with Slit3-deficiency in mice

21 June 2018

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Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney

21 June 2018

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BRCT domain-containing protein PTIP is essential for progression through mitosis

21 June 2018

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HES and HERP families: multiple effectors of the Notch signaling pathway

21 June 2018

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Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development

21 June 2018

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The semaphorin 4D receptor controls invasive growth by coupling with Met

21 June 2018

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The Wilms' tumor gene Wt1 is required for normal development of the retina

21 June 2018

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Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development

21 June 2018

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WT1 proteins: functions in growth and differentiation

21 June 2018

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Targeted mutation of the murine arylhydrocarbon receptor nuclear translocator 2 (Arnt2) gene reveals partial redundancy with Arnt

21 June 2018

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Regulation of blastocyst formation

21 June 2018

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Requirement for the murine zinc finger protein ZFR in perigastrulation growth and survival

21 June 2018

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Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein

21 June 2018

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Characterization of the human and mouse HEY1, HEY2, and HEYL genes: cloning, mapping, and mutation screening of a new bHLH gene family

21 June 2018

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The evolution of gene number: are heritable and non-heritable errors equally important?

21 June 2018

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Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter

21 June 2018

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Proto-oncogene N-myc promoter is down regulated by the Wilms' tumor suppressor gene WT1.

21 June 2018

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The Wilms tumor suppressor gene wt1 is required for development of the spleen.

21 June 2018

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YAC transgenic analysis reveals Wilms' tumour 1 gene activity in the proliferating coelomic epithelium, developing diaphragm and limb.

21 June 2018

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Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud

21 June 2018

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YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis

21 June 2018

1 reference

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A human sequence homologue of Staufen is an RNA-binding protein that is associated with polysomes and localizes to the rough endoplasmic reticulum

21 June 2018

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Sonic hedgehog signaling by the patched-smoothened receptor complex

21 June 2018

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Analysis of WT1 target gene expression in stably transfected cell lines

21 June 2018

1 reference

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Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

21 June 2018

1 reference

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Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

21 June 2018

1 reference

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ARNT-deficient mice and placental differentiation

21 June 2018

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 June 2018

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Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

21 June 2018

1 reference

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BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Pax2 contributes to inner ear patterning and optic nerve trajectory

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

The transcriptional effect of WT1 is modulated by choice of expression vector

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

WT-1 is required for early kidney development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

DNA recognition by splicing variants of the Wilms' tumor suppressor, WT1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

High affinity binding sites for the Wilms' tumour suppressor protein WT1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Repression of Pax-2 by WT1 during normal kidney development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Requirement for neuregulin receptor erbB2 in neural and cardiac development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Vascular endothelial growth factor is a secreted angiogenic mitogen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

The candidate Wilms' tumour gene is involved in genitourinary development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Alternative splicing and genomic structure of the Wilms tumor gene WT1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Expression of the Wilms' tumor gene WT1 in the murine urogenital system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

The genomic organization and expression of the WT1 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

The lymphocyte-specific protein LSP1 binds to F-actin and to the cytoskeleton through its COOH-terminal basic domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Staufen1 is expressed in preimplantation mouse embryos and is required for embryonic stem cell differentiation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Wt1 and retinoic acid signaling are essential for stellate cell development and liver morphogenesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Expression of Plxdc2/TEM7R in the developing nervous system of the mouse.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Sprouty2 and Sprouty4 are essential for embryonic morphogenesis and regulation of FGF signaling.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Dynamics of global gene expression changes during mouse preimplantation development.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

Fgf4 positively regulates scleraxis and tenascin expression in chick limb tendons

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

The cytoskeletal/non-muscle isoform of alpha-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and -independent pathways.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

The cocrystal structures of two zinc-stabilized DNA-binding domains illustrate different ways of achieving sequence-specific DNA recognition.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835332

30 October 2018

Genetics of Wilms' tumor

1 reference

12 December 2020

Vascular permeability factor, an endothelial cell mitogen related to PDGF

1 reference

12 December 2020

BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning

1 reference

12 December 2020

Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling

1 reference

12 December 2020

Identifiers

DOI

10.1242/DEV.045732

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215353%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20215353%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference