Resistance to antimalarial drugs: molecular, pharmacologic, and clinical considerations (Q33723453)

28 July 2017

2 references

18 July 2021

Resistance to antimalarial drugs: molecular, pharmacologic, and clinical considerations (English)

1 reference

28 July 2017

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Plasmodium falciparum

1 reference

18 July 2021

Miriam K Laufer

2

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author name string

Mark A Travassos

series ordinal

1

1 reference

28 July 2017

language of work or name

English

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publication date

1 May 2009

2 references

28 July 2017

18 July 2021

2 references

28 July 2017

18 July 2021

65

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28 July 2017

issue

5 Pt 2

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28 July 2017

page(s)

64R-70R

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Evidence of Artemisinin-Resistant Malaria in Western Cambodia

28 July 2017

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1 reference

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14 July 2018

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The impact of HIV-1 on the malaria parasite biomass in adults in sub-Saharan Africa contributes to the emergence of antimalarial drug resistance

14 July 2018

1 reference

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No PfATPase6 S769N mutation found in Plasmodium falciparum isolates from China

14 July 2018

1 reference

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Antimalarial drug quality in the most severely malarious parts of Africa - a six country study

14 July 2018

1 reference

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Qinghaosu (Artemisinin): The Price of Success

14 July 2018

1 reference

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Simplified antimalarial therapeutic monitoring: using the day-7 drug level?

14 July 2018

1 reference

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Efficacy, safety, and selection of molecular markers of drug resistance by two ACTs in Mali

14 July 2018

1 reference

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Pharmacokinetic determinants of the window of selection for antimalarial drug resistance

14 July 2018

1 reference

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A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia

14 July 2018

1 reference

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Antimalarial dosing regimens and drug resistance

14 July 2018

1 reference

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A network to monitor antimalarial drug resistance: a plan for moving forward

14 July 2018

1 reference

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Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance

14 July 2018

1 reference

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World Antimalarial Resistance Network (WARN) IV: clinical pharmacology

14 July 2018

1 reference

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Effect of sulfadoxine-pyrimethamine resistance on the efficacy of intermittent preventive therapy for malaria control during pregnancy: a systematic review

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Molecular surveillance for drug-resistant Plasmodiumfalciparum malaria in Malawi

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Chloroquine resistant P. falciparum prevalence is low and unchanged between 1990 and 2005 in Guinea-Bissau: an effect of high chloroquine dosage?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from São Tomé and Príncipe

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Quality control of active ingredients in artemisinin-derivative antimalarials within Kenya and DR Congo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Mutations in plasmodium falciparum chloroquine resistance transporter and multidrug resistance genes, and treatment outcomes in Ghanaian children with uncomplicated malaria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Return of chloroquine antimalarial efficacy in Malawi.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Transporters involved in resistance to antimalarial drugs.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Surveillance of the efficacy of artesunate and mefloquine combination for the treatment of uncomplicated falciparum malaria in Cambodia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Antimalarial drugs: recent advances in molecular determinants of resistance and their clinical significance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

In vivo sensitivity monitoring of mefloquine monotherapy and artesunate-mefloquine combinations for the treatment of uncomplicated falciparum malaria in Thailand in 2003.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Complex dynamics and stability of resistance to antimalarial drugs.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Erythrocyte variants and the nature of their malaria protective effect

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

pfcrt is more than the Plasmodium falciparum chloroquine resistance gene: a functional and evolutionary perspective

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Mechanisms of resistance of malaria parasites to antifolates

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Intercontinental spread of pyrimethamine-resistant malaria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Activities of artesunate and primaquine against asexual- and sexual-stage parasites in falciparum malaria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Artemisinins target the SERCA of Plasmodium falciparum

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

The mortality consequences of the continued use of chloroquine in Africa: experience in Siaya, western Kenya

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Treatment of children with Plasmodium falciparum malaria with chloroquine in Guinea-Bissau.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Epidemiology of drug-resistant malaria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Chloroquine-resistant malaria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Evidence for a reduced effect of chloroquine against Plasmodium falciparum in alpha-thalassaemic children

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

A molecular marker for chloroquine-resistant falciparum malaria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Mefloquine pharmacokinetic-pharmacodynamic models: implications for dosing and resistance.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Effects of alpha-thalassemia on pharmacokinetics of the antimalarial agent artesunate.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Treatment of Plasmodium falciparum malaria with pyrimethamine-sulfadoxine: selective pressure for resistance is a function of long elimination half-life

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Resistance to artemisinin of malaria parasites (Plasmodium falciparum) infecting alpha-thalassemic erythrocytes in vitro. Competition in drug accumulation with uninfected erythrocytes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Absence of malaria mortality in villagers with chloroquine-resistant Plasmodium falciparum treated with chloroquine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Chloroquine-resistant Plasmodium falciparum malaria in Senegal

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

A shared Asian origin of the triple-mutant dhfr allele in Plasmodium falciparum from sites across Africa

14 July 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E3181A0977E

In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E3181A0977E

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E3181A0977E

Coartem (artemether-lumefantrine) in Africa: the beginning of the end?

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E3181A0977E

Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr1 86Y.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E3181A0977E

Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E3181A0977E

The Interaction between HIV and malaria in Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E3181A0977E

Malaria treatment efficacy among people living with HIV: the role of host and parasite factors.

21 January 2018

1 reference

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Pfmdr1 and in vivo resistance to artesunate-mefloquine in falciparum malaria on the Cambodian-Thai border.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Observations on monthly pyrimethamine (daraprim) prophylaxis in an East African village.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

Recrudescence in artesunate-treated patients with falciparum malaria is dependent on parasite burden not on parasite factors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837525

10.1203/PDR.0B013E3181A0977E

30 October 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference