Developments towards antiviral therapies against enterovirus 71. (Q33727514)

28 July 2017

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Developments towards antiviral therapies against enterovirus 71. (English)

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28 July 2017

Kan X Wu

1

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28 July 2017

Mary M-L Ng

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2

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28 July 2017

Justin J H Chu

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3

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28 July 2017

23 October 2010

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28 July 2017

1 December 2010

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22 October 2022

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28 July 2017

22 October 2022

15

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28 July 2017

23-24

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28 July 2017

1041-1051

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Design, synthesis, and structure-activity relationship of pyridyl imidazolidinones: a novel class of potent and selective human enterovirus 71 inhibitors

28 July 2017

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12 December 2020

Sialylated glycans as receptor and inhibitor of enterovirus 71 infection to DLD-1 intestinal cells

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12 December 2020

Poliovirus 2C region functions during encapsidation of viral RNA.

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12 December 2020

Selective human enterovirus and rhinovirus inhibitors: An overview of capsid-binding and protease-inhibiting molecules

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12 December 2020

Inhibitors of picornavirus uncoating as antiviral agents

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12 December 2020

Molecular evolution of the human enteroviruses: correlation of serotype with VP1 sequence and application to picornavirus classification

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12 December 2020

Synthesis, antiviral activity, and biological properties of vinylacetylene analogs of enviroxime

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12 December 2020

Enterovirus 71 infection of human dendritic cells

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12 December 2020

Selective inhibition of enterovirus 71 replication by short hairpin RNAs

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12 December 2020

Neural pathogenesis of enterovirus 71 infection

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12 December 2020

Therapeutic activity of enviroxime against rhinovirus infection in volunteers

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12 December 2020

Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71.

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12 December 2020

Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylation

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12 December 2020

Involvement of cellular membrane traffic proteins in poliovirus replication

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12 December 2020

An apparently new enterovirus isolated from patients with disease of the central nervous system

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12 December 2020

Fomivirsen approved for CMV retinitis

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12 December 2020

Heparin-mimicking sulfonic acid polymers as multitarget inhibitors of human immunodeficiency virus type 1 Tat and gp120 proteins

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12 December 2020

Critical management in patients with severe enterovirus 71 infection

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12 December 2020

Studies with poliovirus polymerase 3Dpol. Stimulation of poly(U) synthesis in vitro by purified poliovirus protein 3AB.

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12 December 2020

Antiviral effect of epigallocatechin gallate on enterovirus 71.

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12 December 2020

Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307.

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12 December 2020

P-selectin glycoprotein ligand-1 is broadly expressed in cells of myeloid, lymphoid, and dendritic lineage and in some nonhematopoietic cells.

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12 December 2020

Reticulon 3 Binds the 2C Protein of Enterovirus 71 and Is Required for Viral Replication

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12 December 2020

Lactoferrin inhibits enterovirus 71 infection by binding to VP1 protein and host cells

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12 December 2020

Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication.

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12 December 2020

Sequence determinants of 3A-mediated resistance to enviroxime in rhinoviruses and enteroviruses

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12 December 2020

The 1998 enterovirus 71 outbreak in Taiwan: pathogenesis and management

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12 December 2020

Regulation of picornavirus gene expression

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12 December 2020

Aloe-emodin is an interferon-inducing agent with antiviral activity against Japanese encephalitis virus and enterovirus 71.

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12 December 2020

The efficacy of viral capsid inhibitors in human enterovirus infection and associated diseases

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12 December 2020

The 3C protease activity of enterovirus 71 induces human neural cell apoptosis

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12 December 2020

Ribavirin reduces mortality in enterovirus 71-infected mice by decreasing viral replication

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12 December 2020

Cellular kinase inhibitors that suppress enterovirus replication have a conserved target in viral protein 3A similar to that of enviroxime.

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12 December 2020

In vitro activity of expanded-spectrum pyridazinyl oxime ethers related to pirodavir: novel capsid-binding inhibitors with potent antipicornavirus activity

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12 December 2020

Neurodevelopment and Cognition in Children after Enterovirus 71 Infection

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12 December 2020

In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease

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12 December 2020

Antiviral activity of raoulic acid from Raoulia australis against Picornaviruses

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12 December 2020

Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity

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12 December 2020

RNA interference against enterovirus 71 infection

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12 December 2020

Identification of small interfering RNAs which inhibit the replication of several Enterovirus 71 strains in China.

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12 December 2020

Rhinovirus chemotherapy

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12 December 2020

Daily or three times a week interferon alfa-2b in combination with ribavirin or interferon alone for the treatment of patients with chronic hepatitis C.

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12 December 2020

Infection with enterovirus 71 or expression of its 2A protease induces apoptotic cell death

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12 December 2020

Retrograde axonal transport: a major transmission route of enterovirus 71 in mice

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12 December 2020

SCH 48973: a potent, broad-spectrum, antienterovirus compound

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12 December 2020

Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid

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12 December 2020

Progress toward interruption of wild poliovirus transmission--worldwide, 2008.

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12 December 2020

Type I interferons protect mice against enterovirus 71 infection

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12 December 2020

Activity of pleconaril against enteroviruses

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12 December 2020

Current status of anti-picornavirus therapies

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12 December 2020

Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents.

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12 December 2020

Enterovirus infections with special reference to enterovirus 71.

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12 December 2020

Antiviral activities of extracts and selected pure constituents of Ocimum basilicum

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12 December 2020

In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviral activity

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12 December 2020

Real-time monitoring of human enterovirus (HEV)-infected cells and anti-HEV 3C protease potency by fluorescence resonance energy transfer

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12 December 2020

Inhibition of enterovirus 71 in virus-infected mice by RNA interference.

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12 December 2020

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

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12 December 2020

Picornavirus uncoating

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12 December 2020

Anti-HIV effects of chloroquine: inhibition of viral particle glycosylation and synergism with protease inhibitors.

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12 December 2020

Epidemic hand, foot and mouth disease caused by human enterovirus 71, Singapore

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12 December 2020

Implications of high RNA virus mutation rates: lethal mutagenesis and the antiviral drug ribavirin

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12 December 2020

Development of antiviral agents for enteroviruses

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12 December 2020

Protein 3CD is the major poliovirus proteinase responsible for cleavage of the P1 capsid precursor

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12 December 2020

Poliovirus-encoded 2C polypeptide specifically binds to the 3'-terminal sequences of viral negative-strand RNA

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12 December 2020

Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells in vitro

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12 December 2020

Potential use of antiviral agents in polio eradication

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12 December 2020

Inhibition of enterovirus 71-induced apoptosis by allophycocyanin isolated from a blue-green alga Spirulina platensis

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12 December 2020

Selective inhibitors of picornavirus replication

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12 December 2020

Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71.

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12 December 2020

RNA interference against viruses: strike and counterstrike

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12 December 2020

An overview of the evolution of enterovirus 71 and its clinical and public health significance

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12 December 2020

Glucose-6-phosphate dehydrogenase deficiency enhances enterovirus 71 infection

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12 December 2020

Protease inhibitors as antiviral agents.

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12 December 2020

Respiratory syncytial virus (RSV) disease and prospects for its control

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12 December 2020

An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus

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12 December 2020

Amantadine as a regulator of internal ribosome entry site

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12 December 2020

Poliovirus protein 2C has ATPase and GTPase activities

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12 December 2020

Antiviral activity of pyridyl imidazolidinones against enterovirus 71 variants

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12 December 2020

Molecular dissection of the multifunctional poliovirus RNA-binding protein 3AB.

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12 December 2020

Scavenger receptor B2 is a cellular receptor for enterovirus 71

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12 December 2020

Protein-primed RNA synthesis by purified poliovirus RNA polymerase

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12 December 2020

Viral protein synthesis is required for Enterovirus 71 to induce apoptosis in human glioblastoma cells

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12 December 2020

10.1016/J.DRUDIS.2010.10.008

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DOI

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28 July 2017

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