Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation (Q33730095)

29 July 2017

title

Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation (English)

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29 July 2017

1 reference

Sarah L Rowland

1

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29 July 2017

Corinne L DePersis

series ordinal

2

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29 July 2017

Raul M Torres

series ordinal

3

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29 July 2017

Roberta Pelanda

series ordinal

4

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29 July 2017

language of work or name

English

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publication date

22 February 2010

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Journal of Experimental Medicine

29 July 2017

published in

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29 July 2017

volume

207

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29 July 2017

issue

3

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29 July 2017

page(s)

607-621

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Using cells devoid of RAS proteins as tools for drug discovery

29 July 2017

cites work

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Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling.

14 July 2018

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Heparan sulfate and heparin enhance ERK phosphorylation and mediate preBCR-dependent events during B lymphopoiesis

14 July 2018

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14 July 2018

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ITAM-mediated tonic signalling through pre-BCR and BCR complexes

14 July 2018

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Basal immunoglobulin signaling actively maintains developmental stage in immature B cells

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes

14 July 2018

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CD4+ T cells derived from B cell-deficient mice inhibit the establishment of peripheral B cell pools

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen.

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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21 January 2018

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In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion.

21 January 2018

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Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

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A functional B cell receptor transgene allows efficient IL-7-independent maturation of B cell precursors

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Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo

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12 December 2020

Ig allotypic inclusion does not prevent B cell development or response

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Identifiers

DOI

10.1084/JEM.20091673

1 reference

29 July 2017

1 reference

29 July 2017

1 reference