A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha (Q33733874)

29 July 2017

A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha (English)

1 reference

29 July 2017

3

1 reference

29 July 2017

14

Bruce Beutler

1 reference

29 July 2017

Gerald McInerney

11

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Owen M Siggs

object named as

Owen M Siggs

1

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Celine Eidenschenk

5

object named as

Celine Eidenschenk

1 reference

29 July 2017

Michael Berger

2

1 reference

29 July 2017

Carrie N Arnold

4

1 reference

29 July 2017

Christoph Huber

6

1 reference

29 July 2017

Elaine Pirie

7

1 reference

29 July 2017

Nora G Smart

8

1 reference

29 July 2017

Kevin Khovananth

9

1 reference

29 July 2017

Yu Xia

10

1 reference

29 July 2017

Gunilla B Karlsson Hedestam

12

1 reference

29 July 2017

David Nemazee

13

1 reference

29 July 2017

language of work or name

English

0 references

publication date

28 January 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

29 July 2017

107

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29 July 2017

7

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29 July 2017

3046-3051

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Cutting edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Shared principles in NF-kappaB signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

IKBKG (nuclear factor-kappa B essential modulator) mutation can be associated with opportunistic infection without impairing Toll-like receptor function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Nuclear factor kappaB essential modulator-deficient child with immunodeficiency yet without anhidrotic ectodermal dysplasia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

IkappaB kinase is an essential component of the Tpl2 signaling pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

IkappaB kinase signaling is essential for maintenance of mature B cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Gene defect in ectodermal dysplasia implicates a death domain adapter in development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Two-helper RNA system for production of recombinant Semliki forest virus particles.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Natural killer (NK) cell response to virus infections in mice with severe combined immunodeficiency. The stimulation of NK cells and the NK cell-dependent control of virus infections occur independently of T and B cell function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

Proteolysis of NF-kappaB1 p105 is essential for T cell antigen receptor-induced proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

Involvement of a novel Tnf receptor homologue in hair follicle induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

21 January 2018

ENU mutagenesis in mice

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

Human nuclear factor kappa B essential modulator mutation can result in immunodeficiency without ectodermal dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF in LPS-stimulated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

Mature T cells depend on signaling through the IKK complex.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840324

Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

30 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

Epithelial NEMO links innate immunity to chronic intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915098107

Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20133626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0915098107

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference