Polyglutamine diseases: protein cleavage and aggregation. (Q33745319)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10508741%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

review article

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title

Polyglutamine diseases: protein cleavage and aggregation (English)

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31 October 2019

1

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31 October 2019

Harry T. Orr

series ordinal

2

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31 October 2019

author name string

Orr HT

series ordinal

2

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29 July 2017

1 October 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10508741%20AND%20SRC:MED&resulttype=core&format=json

Current Opinion in Neurobiology

31 October 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10508741%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

volume

9

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31 October 2019

issue

5

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31 October 2019

page(s)

566-570

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Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegenerative diseases?

31 October 2019

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Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

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Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

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Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

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Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions?

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Glutamine repeats and neurodegenerative diseases: molecular aspects

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Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

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Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro

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Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

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Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

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Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy

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The influence of huntingtin protein size on nuclear localization and cellular toxicity.

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7 January 2021

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

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A cellular model that recapitulates major pathogenic steps of Huntington's disease

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Protease activation during apoptosis: death by a thousand cuts?

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7 January 2021

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

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7 January 2021

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

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7 January 2021

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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

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SAPKs and transcription factors do the nucleocytoplasmic tango

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7 January 2021

10.1016/S0959-4388(99)00013-6

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10508741%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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