Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease (Q33745617)

29 July 2017

title

Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease (English)

1 reference

29 July 2017

0 references

1

David A Bennett

1 reference

29 July 2017

3

Philip L De Jager

1 reference

29 July 2017

Lei Yu

2

1 reference

29 July 2017

language of work or name

English

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publication date

6 February 2014

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29 July 2017

number of pages

14

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based on heuristic

inferred from page(s)

published in

Biochemical Pharmacology

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29 July 2017

volume

88

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29 July 2017

issue

4

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29 July 2017

page(s)

617-630

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Brain tocopherols related to Alzheimer's disease neuropathology in humans

29 July 2017

cites work

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21 June 2018

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CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility

21 June 2018

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Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Successes and failures for drugs in late-stage development for Alzheimer's disease

21 June 2018

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Using a body-fixed sensor to identify subclinical gait difficulties in older adults with IADL disability: maximizing the output of the timed up and go

21 June 2018

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The role of autophagy in neurodegenerative disease

21 June 2018

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Genetic susceptibility for Alzheimer disease neuritic plaque pathology

21 June 2018

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Temporal Discounting Is Associated with an Increased Risk of Mortality among Community-Based Older Persons without Dementia

21 June 2018

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21 June 2018

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Beyond amyloid: getting real about nonamyloid targets in Alzheimer's disease

21 June 2018

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Much of late life cognitive decline is not due to common neurodegenerative pathologies.

21 June 2018

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Ushering in the study and treatment of preclinical Alzheimer disease

21 June 2018

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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

21 June 2018

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Comparative analysis of RNA sequencing methods for degraded or low-input samples

21 June 2018

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Principal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes

21 June 2018

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APOE ε4, Alzheimer's disease pathology, cerebrovascular disease, and cognitive change over the years prior to death

21 June 2018

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Clinical trials in predementia stages of Alzheimer disease

21 June 2018

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21 June 2018

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21 June 2018

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Brain amyloid-β oligomers in ageing and Alzheimer's disease

21 June 2018

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21 June 2018

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21 June 2018

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Alternative Approaches in Gene Discovery and Characterization in Alzheimer's Disease

21 June 2018

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21 June 2018

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Microvascular brain pathology and late-life motor impairment

21 June 2018

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Apolipoprotein E and change in episodic memory in blacks and whites

21 June 2018

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Proteome-wide selected reaction monitoring assays for the human pathogen Streptococcus pyogenes

21 June 2018

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Preclinical Alzheimer disease-the challenges ahead

21 June 2018

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Alzheimer's therapeutics: continued clinical failures question the validity of the amyloid hypothesis-but what lies beyond?

21 June 2018

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Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network

21 June 2018

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21 June 2018

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Functional connectivity networks associated with chronic musculoskeletal pain in old age

21 June 2018

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Relation of neuropathology to cognition in persons without cognitive impairment

21 June 2018

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Longitudinal modeling of cognitive aging and the TOMM40 effect

21 June 2018

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Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress

21 June 2018

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Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology

21 June 2018

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21 June 2018

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Risk Aversion is Associated with Decision Making among Community-Based Older Persons

21 June 2018

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21 June 2018

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Advancing the sensitivity of selected reaction monitoring-based targeted quantitative proteomics

21 June 2018

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Session II: Mechanisms of age-related cognitive change and targets for intervention: neural circuits, networks, and plasticity

21 June 2018

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Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age

21 June 2018

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New and emerging treatments for Alzheimer's disease.

21 June 2018

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Cholinesterase inhibitors and memantine for symptomatic treatment of dementia

21 June 2018

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Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

21 June 2018

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Alzheimer disease susceptibility loci: evidence for a protein network under natural selection

21 June 2018

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Overview and findings from the rush Memory and Aging Project

21 June 2018

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The Framingham Brain Donation Program: neuropathology along the cognitive continuum

21 June 2018

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Identification of biomarkers in Lewy-body disorders

21 June 2018

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A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline

21 June 2018

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Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature

21 June 2018

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National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

21 June 2018

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Brain imaging in the study of Alzheimer's disease

21 June 2018

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The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease

21 June 2018

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Twenty years of Alzheimer's disease-causing mutations

21 June 2018

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Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor

21 June 2018

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Systematic discovery of TLR signaling components delineates viral-sensing circuits

21 June 2018

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Potential of functional MRI as a biomarker in early Alzheimer's disease

21 June 2018

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Blood-based biomarkers for Alzheimer's disease: plasma Aβ40 and Aβ42, and genetic variants

21 June 2018

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A genome-wide scan for common variants affecting the rate of age-related cognitive decline

21 June 2018

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Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast

21 June 2018

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Current and emerging drug treatment options for Alzheimer's disease: a systematic review.

21 June 2018

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Treatment of dementia with Lewy bodies and Parkinson's disease dementia

21 June 2018

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Alzheimer's therapeutics: translation of preclinical science to clinical drug development

21 June 2018

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A phase 2 randomized trial of ELND005, scyllo-inositol, in mild to moderate Alzheimer disease

21 June 2018

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Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial

21 June 2018

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A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease

21 June 2018

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Extended results of the Alzheimer's disease anti-inflammatory prevention trial

21 June 2018

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Prevalence of asymptomatic vasogenic edema in pretreatment Alzheimer's disease study cohorts from phase 3 trials of semagacestat and solanezumab

21 June 2018

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21 June 2018

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Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association

21 June 2018

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Tau as a therapeutic target for Alzheimer's disease

21 June 2018

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Risk factors and preventive interventions for Alzheimer disease: state of the science

21 June 2018

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The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

21 June 2018

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The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Selected reaction monitoring applied to proteomics.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

CR1 is associated with amyloid plaque burden and age-related cognitive decline

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Cerebral amyloid angiopathy pathology and cognitive domains in older persons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Epidemiology of Alzheimer disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Functional screening of Alzheimer pathology genome-wide association signals in Drosophila

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The genetics of Alzheimer disease: back to the future

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Neurodegenerative basis of age-related cognitive decline

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Comprehensive comparative analysis of strand-specific RNA sequencing methods

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Atherosclerosis, dementia, and Alzheimer disease in the Baltimore Longitudinal Study of Aging cohort

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Contribution of systemic inflammation to chronic neurodegeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Intermediate phenotypes identify divergent pathways to Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Probing the biology of Alzheimer's disease in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Pathologic correlates of dementia in individuals with Lewy body disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Enhanced sensitivity for selected reaction monitoring mass spectrometry-based targeted proteomics using a dual stage electrodynamic ion funnel interface.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Current strategies for diversity-oriented synthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Oxidative stress in Alzheimer disease: a possibility for prevention

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Biomarkers: Parkinson disease with dementia and dementia with Lewy bodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Amyloid-beta immunotherapy for Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The secretases: enzymes with therapeutic potential in Alzheimer disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

BEDTools: a flexible suite of utilities for comparing genomic features

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Longitudinal study of the transition from healthy aging to Alzheimer disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Promising strategies for the prevention of dementia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The neuropathology of probable Alzheimer disease and mild cognitive impairment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Neuropathologic studies of the Baltimore Longitudinal Study of Aging (BLSA)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Anti-amyloid treatments in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Prodromal Alzheimer's disease: successive emergence of the clinical symptoms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

A multi-center, randomized, double blind placebo-controlled trial of estrogens to prevent Alzheimer's disease and loss of memory in women: design and baseline characteristics.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Model-based analysis of ChIP-Seq (MACS)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Mapping short DNA sequencing reads and calling variants using mapping quality scores

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Cardiovascular risk factors and incident Alzheimer disease: a systematic review of the literature

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The neural correlate of consciousness

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Effectiveness of Cholinesterase Inhibitors and Memantine for Treating Dementia: Evidence Review for a Clinical Practice Guideline

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Memory impairment, executive dysfunction, and intellectual decline in preclinical Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Anterior cingulate cortex and conflict detection: an update of theory and data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Confounding in the Estimation of Mediation Effects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

PLINK: a tool set for whole-genome association and population-based linkage analyses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Selective involvement of the mid-dorsolateral prefrontal cortex in the coding of the serial order of visual stimuli in working memory

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The Parieto-Frontal Integration Theory (P-FIT) of intelligence: Converging neuroimaging evidence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Chronic distress and incidence of mild cognitive impairment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The dorsolateral prefrontal cortex contributes to successful relational memory encoding.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Characterization of Japanese-American men with a single neocortical AD lesion type

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

AD brain pathology: vascular origins? Results from the HAAS autopsy study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Dorsolateral prefrontal cortex, working memory, and prospective coding for action.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Transcriptome alterations in schizophrenia: disturbing the functional architecture of the dorsolateral prefrontal cortex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Relevance of cardiovascular risk factors and ischemic cerebrovascular disease to the pathogenesis of Alzheimer disease: a review of accrued findings from the Honolulu-Asia Aging Study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Principal components analysis corrects for stratification in genome-wide association studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Involvement of human left dorsolateral prefrontal cortex in perceptual decision making is independent of response modality

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Motor learning in man: a review of functional and clinical studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Neuropathologic features of amnestic mild cognitive impairment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Prefrontal modulation of working memory performance in brain injury and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Interfering with working memory in humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Functional specialization within the dorsolateral prefrontal cortex: a review of anatomical and physiological studies of non-human primates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Neural mechanisms of imitation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Early and late life cognitive activity and cognitive systems in old age.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Amyloid mediates the association of apolipoprotein E e4 allele to cognitive function in older people

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Common fronto-parietal activity in attention, memory, and consciousness: shared demands on integration?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The 9 year cognitive decline before dementia of the Alzheimer type: a prospective population-based study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The apolipoprotein E epsilon 2 allele and decline in episodic memory

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Natural history of mild cognitive impairment in older persons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year period

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Individual differences in rates of change in cognitive abilities of older persons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Safety and biomarker effects of solanezumab in patients with Alzheimer's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Biomarkers in Alzheimer's disease drug development.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Differences in metabolites in pain-processing brain regions in patients with diabetes and painful neuropathy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Trajectory of mild cognitive impairment onset.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Biochemical characterization of Abeta and tau pathologies in mild cognitive impairment and Alzheimer's disease.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Longitudinal trajectories of cognitive change in preclinical Alzheimer's disease: a growth mixture modeling analysis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Pathological correlates of dementia in a longitudinal, population-based sample of aging.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Loneliness and risk of Alzheimer disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Estimation of the mediation effect with a binary mediator.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Decision rules guiding the clinical diagnosis of Alzheimer's disease in two community-based cohort studies compared to standard practice in a clinic-based cohort study

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Dorsolateral prefrontal cortex promotes long-term memory formation through its role in working memory organization.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Predictors of preclinical Alzheimer disease and dementia: a clinicopathologic study.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Modulation of prefrontal cortex activity by information toward a decision rule.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054869

Exploring candidate gene associations with neuropsychological performance

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24508835

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multicenter, randomized, double-blind, placebo-controlled, single-ascending dose study of the oral γ-secretase inhibitor BMS-708163 (Avagacestat): tolerability profile, pharmacokinetic parameters, and pharmacodynamic markers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24508835

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BCP.2014.01.037

1 reference

29 July 2017

1 reference

29 July 2017

1 reference