p38 regulates pigmentation via proteasomal degradation of tyrosinase (Q33748070)

29 July 2017

p38 regulates pigmentation via proteasomal degradation of tyrosinase (English)

1 reference

29 July 2017

Barbara Bellei

1

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Enrica Flori

object named as

Enrica Flori

3

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Mauro Picardo

object named as

Mauro Picardo

6

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author name string

Vittoria Maresca

2

1 reference

29 July 2017

Angela Pitisci

4

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29 July 2017

Lionel Larue

5

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29 July 2017

language of work or name

English

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publication date

6 January 2010

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Journal of Biological Chemistry

29 July 2017

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29 July 2017

285

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29 July 2017

10

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29 July 2017

7288-7299

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Fermented rice bran downregulates MITF expression and leads to inhibition of alpha-MSH-induced melanogenesis in B16F1 melanoma

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

GSK3beta inhibition promotes melanogenesis in mouse B16 melanoma cells and normal human melanocytes

21 June 2018

1 reference

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Specific inhibitor of MEK-mediated cross-talk between ERK and p38 MAPK during differentiation of human osteosarcoma cells

21 June 2018

1 reference

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Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Rosmarinic acid induces melanogenesis through protein kinase A activation signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Additive effects of heat and p38 MAPK inhibitor treatment on melanin synthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Glycogen synthase kinase-3beta and p38 phosphorylate cyclin D2 on Thr280 to trigger its ubiquitin/proteasome-dependent degradation in hematopoietic cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Role of the mitogen-activated protein kinase signaling pathway in the regulation of human melanocytic antigen expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Human placental lipid induces melanogenesis through p38 MAPK in B16F10 mouse melanoma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

P38SAPK2 phosphorylates cyclin D3 at Thr-283 and targets it for proteasomal degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

(-)-Epigallocatechin-3-gallate and hinokitiol reduce melanin synthesis via decreased MITF production

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Fatty acids regulate pigmentation via proteasomal degradation of tyrosinase: a new aspect of ubiquitin-proteasome function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Suppression by p38 MAP kinase inhibitors (pyridinyl imidazole compounds) of Ah receptor target gene activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin and the possible mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Sphingosine-1-phosphate decreases melanin synthesis via sustained ERK activation and subsequent MITF degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Inhibition of melanogenesis in response to oxidative stress: transient downregulation of melanocyte differentiation markers and possible involvement of microphthalmia transcription factor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Mammalian MAP kinase signalling cascades

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Up-regulation of tyrosinase gene by nitric oxide in human melanocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Cell-density-dependent regulation of expression and glycosylation of dopachrome tautomerase/tyrosinase-related protein-2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Targeting the microphthalmia basic helix-loop-helix-leucine zipper transcription factor to a subset of E-box elements in vitro and in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Different cis-acting elements are involved in the regulation of TRP1 and TRP2 promoter activities by cyclic AMP: pivotal role of M boxes (GTCATGTGCT) and of microphthalmia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Nitric oxide produced by ultraviolet-irradiated keratinocytes stimulates melanogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Ultraviolet B radiation acts through the nitric oxide and cGMP signal transduction pathway to stimulate melanogenesis in human melanocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Ectopic expression of MITF, a gene for Waardenburg syndrome type 2, converts fibroblasts to cells with melanocyte characteristics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Piebald lethal (sl) acts early to disrupt the development of neural crest-derived melanocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

The tyrosinase gene family--interactions of melanogenic proteins to regulate melanogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Regulation of tyrosinase in human melanocytes grown in culture

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Melanocyte-stimulating hormone promotes activation of pre-existing tyrosinase molecules in Cloudman S91 melanoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

The dual effect of melanocyte-stimulating hormone (MSH) on the growth of cultured mouse melanoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844177

Melanin formation in the inner ear is catalyzed by a new tyrosine hydroxylase kinetically and structurally different from tyrosinase.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Analysis of the UV-induced melanogenesis and growth arrest of human melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Role of p38 MAPK in Lupeol-Induced B16 2F2 Mouse Melanoma Cell Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

LPS induces melanogenesis through p38 MAPK activation in human melanocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Microphthalmia associated transcription factor is a target of the phosphatidylinositol-3-kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Post-transcriptional regulation of melanin biosynthetic enzymes by cAMP and resveratrol in human melanocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Regulation of melanocortin 1 receptor expression at the mRNA and protein levels by its natural agonist and antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Delayed ERK activation by ceramide reduces melanin synthesis in human melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Sphingosylphosphorylcholine-induced ERK activation inhibits melanin synthesis in human melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Differentiation of human melanoma cells through p38 MAP kinase is associated with decreased retinoblastoma protein phosphorylation and cell cycle arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Inhibition of nucleoside transport by p38 MAPK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Regulation of tyrosinase processing and trafficking by organellar pH and by proteasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Regulation of tyrosinase-related protein-2 (TYRP2) in human melanocytes: relationship to growth and morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

PD98059 enhances C2 myoblast differentiation through p38 MAPK activation: a novel role for PD98059.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070573

Alpha-melanocyte stimulating hormone-induced pigmentation is blocked by depletion of protein kinase C

21 January 2018

1 reference

12 December 2020

In situ melanin assay for MSH using mouse B16 melanoma cells in culture

1 reference

12 December 2020

Control of melanin synthesis and secretion by B16/C3 melanoma cells

1 reference

12 December 2020

Alpha-melanocyte-stimulating hormone regulation of tyrosinase in Cloudman S-91 mouse melanoma cell cultures

1 reference

12 December 2020

Increased level of p27 subunit of proteasomes and its co-localization with tyrosinase in amelanotic melanoma cells indicate its direct role in the regulation of melanin biosynthesis

1 reference

12 December 2020

The beta isoform of protein kinase C stimulates human melanogenesis by activating tyrosinase in pigment cells

1 reference

12 December 2020

In B16 melanoma cells, the inhibition of melanogenesis by TPA results from PKC activation and diminution of microphthalmia binding to the M-box of the tyrosinase promoter

1 reference

12 December 2020

Protein kinase C-beta activates tyrosinase by phosphorylating serine residues in its cytoplasmic domain

1 reference

12 December 2020

The involvement of p38 mitogen-activated protein kinase in the alpha-melanocyte stimulating hormone (alpha-MSH)-induced melanogenic and anti-proliferative effects in B16 murine melanoma cells

1 reference

12 December 2020

Activation of the cyclic AMP pathway by alpha-melanotropin mediates the response of human melanocytes to ultraviolet B radiation

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.070573

1 reference

29 July 2017

1 reference

29 July 2017

1 reference