Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis (Q33754644)

29 July 2017

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis (English)

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29 July 2017

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Anurag Purushothaman

1

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29 July 2017

Toru Uyama

2

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29 July 2017

Fumi Kobayashi

3

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29 July 2017

Shuhei Yamada

4

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29 July 2017

Kazuyuki Sugahara

5

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29 July 2017

Alan C Rapraeger

6

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29 July 2017

Ralph D Sanderson

7

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29 July 2017

language of work or name

English

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publication date

22 January 2010

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29 July 2017

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29 July 2017

115

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29 July 2017

2449-2457

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12

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describes a project that uses

29 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2845901/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Syndecan-1 is required for robust growth, vascularization, and metastasis of myeloma tumors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Heparanase regulates levels of syndecan-1 in the nucleus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Cell surface heparan sulfate released by heparanase promotes melanoma cell migration and angiogenesis

21 June 2018

1 reference

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Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myeloma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Molecular and cellular mechanisms of syndecans in tissue injury and inflammation

21 June 2018

1 reference

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Heparan sulfate control of proliferation and differentiation in the stem cell niche

21 June 2018

1 reference

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Mechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis

21 June 2018

1 reference

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The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Tinkering with heparan sulfate sulfation to steer development

21 June 2018

1 reference

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The role of syndecans in disease and wound healing

21 June 2018

1 reference

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Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis

21 June 2018

1 reference

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Spatial and temporal heparanase expression in colon mucosa throughout the adenoma-carcinoma sequence

21 June 2018

1 reference

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Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Syndecan-1 expression by stromal fibroblasts promotes breast carcinoma growth in vivo and stimulates tumor angiogenesis

21 June 2018

1 reference

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Enzymatic remodeling of heparan sulfate proteoglycans within the tumor microenvironment: growth regulation and the prospect of new cancer therapies.

21 June 2018

1 reference

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The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

VEGF signalling: integration and multi-tasking in endothelial cell biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Soluble syndecan-1 promotes growth of myeloma tumors in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Oversulfated chondroitin/dermatan sulfates containing GlcAbeta1/IdoAalpha1-3GalNAc(4,6-O-disulfate) interact with L- and P-selectin and chemokines

21 June 2018

1 reference

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Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

The splice variants of vascular endothelial growth factor (VEGF) and their receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

High levels of soluble syndecan-1 in myeloma-derived bone marrow: modulation of hepatocyte growth factor activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Functions of cell surface heparan sulfate proteoglycans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

VEGF121, a vascular endothelial growth factor (VEGF) isoform lacking heparin binding ability, requires cell-surface heparan sulfates for efficient binding to the VEGF receptors of human melanoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Requirement of vascular integrin alpha v beta 3 for angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Extracellular matrix-resident growth factors and enzymes: possible involvement in tumor metastasis and angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Structural and functional changes of sulfated glycosaminoglycans in Xenopus laevis during embryogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Heparin regulates vascular endothelial growth factor165-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells. Comparison of the effects of heparin and modified heparins

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparin-binding proteins.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845901

Serum syndecan-1: a new independent prognostic marker in multiple myeloma

30 October 2018

1 reference

12 December 2020

High heparanase activity in multiple myeloma is associated with elevated microvessel density

1 reference

12 December 2020

Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion

1 reference

12 December 2020

The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules

1 reference

12 December 2020

Microanalysis of glycosaminoglycan-derived oligosaccharides labeled with a fluorophore 2-aminobenzamide by high-performance liquid chromatography: application to disaccharide composition analysis and exosequencing of oligosaccharides

1 reference

12 December 2020

Syndecan-1 and angiogenic cytokines in multiple myeloma: correlation with bone marrow angiogenesis and survival

1 reference

12 December 2020

Heparanase promotes the spontaneous metastasis of myeloma cells to bone

1 reference

12 December 2020

Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis

1 reference

12 December 2020

Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis

1 reference

12 December 2020

Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate

1 reference

12 December 2020

10.1182/BLOOD-2009-07-234757

Identifiers

DOI

1 reference

release_w652qkvo4rccpkaapkvmegcmim

29 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/w652qkvo4rccpkaapkvmegcmim

24 November 2022

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PMCID

2845901

1 reference

29 July 2017

1 reference