TCF transcription factors: molecular switches in carcinogenesis (Q33755135)

29 July 2017

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title

TCF transcription factors: molecular switches in carcinogenesis (English)

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29 July 2017

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J Roose

1

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29 July 2017

H Clevers

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 October 1999

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Biochimica et Biophysica Acta

29 July 2017

published in

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29 July 2017

volume

1424

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29 July 2017

issue

2-3

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29 July 2017

page(s)

M23-37

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beta-catenin is a target for the ubiquitin-proteasome pathway

29 July 2017

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A gene family of HMG-box transcription factors with homology to TCF-1

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Drosophila Tcf and Groucho interact to repress Wingless signalling activity.

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TCF/LEF factor earn their wings

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Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

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Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis

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Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice

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7 January 2021

A common ancestor of the mammalian transcription factors TCF-1 and TCF-1 alpha/LEF-1 expressed in chicken T cells

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7 January 2021

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

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7 January 2021

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

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7 January 2021

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

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Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

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Control points in early T-cell development

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Gut reaction to Wnt signaling in worms

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

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7 January 2021

A deduced gene product from the Drosophila neurogenic locus, enhancer of split, shows homology to mammalian G-protein beta subunit

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7 January 2021

A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo

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7 January 2021

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

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7 January 2021

Identification of c-MYC as a target of the APC pathway

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7 January 2021

Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos

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7 January 2021

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

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7 January 2021

The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.

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7 January 2021

Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed

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7 January 2021

Lessons from hereditary colorectal cancer

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7 January 2021

The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal

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7 January 2021

Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development

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7 January 2021

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

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7 January 2021

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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7 January 2021

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

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7 January 2021

Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development

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7 January 2021

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

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7 January 2021

Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures.

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7 January 2021

pop-1 Encodes an HMG box protein required for the specification of a mesoderm precursor in Early C. elegans embryos

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7 January 2021

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation

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7 January 2021

Structural basis for DNA bending by the architectural transcription factor LEF-1

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7 January 2021

Cloning and developmental expression of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex

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7 January 2021

Distinct roles for P-CREB and LEF-1 in TCR alpha enhancer assembly and activation on chromatin templates in vitro

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7 January 2021

The human high mobility group (HMG)-box transcription factor TCF-1: novel isoforms due to alternative splicing and usage of a new exon IXA

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7 January 2021

Ectopic activation of lymphoid high mobility group-box transcription factor TCF-1 and overexpression in colorectal cancer cells

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7 January 2021

A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin

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7 January 2021

Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis.

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7 January 2021

MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans

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7 January 2021

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

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7 January 2021

Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein

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7 January 2021

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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7 January 2021

Differential expression of the HMG box transcription factors XTcf-3 and XLef-1 during early xenopus development

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7 January 2021

WNTs modulate cell fate and behavior during vertebrate development

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7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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7 January 2021

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

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7 January 2021

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

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7 January 2021

Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin

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7 January 2021

dishevelled and armadillo act in the wingless signalling pathway in Drosophila

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7 January 2021

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

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7 January 2021

Mutations affecting segment number and polarity in Drosophila

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7 January 2021

Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers

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7 January 2021

Cell-cell signalling: Wingless lands at last

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7 January 2021

Groucho: making its Marx as a transcriptional co-repressor.

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7 January 2021

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

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7 January 2021

The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties

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7 January 2021

Phosphorylation of the Drosophila adherens junction protein Armadillo: roles for wingless signal and zeste-white 3 kinase.

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7 January 2021

How a growth control path takes a wrong turn to cancer

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7 January 2021

Products of the grg (Groucho-related gene) family can dimerize through the amino-terminal Q domain

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7 January 2021

The oncogenic activation of beta-catenin

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7 January 2021

LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.

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7 January 2021

The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless

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7 January 2021

Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos

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7 January 2021

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

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7 January 2021

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

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7 January 2021

Stabilization of beta-catenin by genetic defects in melanoma cell lines

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7 January 2021

Association of the APC gene product with beta-catenin

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7 January 2021

The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin

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7 January 2021

The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins

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7 January 2021

Components of wingless signalling in Drosophila.

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7 January 2021

Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

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7 January 2021

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

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7 January 2021

Association of the APC tumor suppressor protein with catenins

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7 January 2021

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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7 January 2021

Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm

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7 January 2021

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

1 reference

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7 January 2021

Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact

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https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

An HMG-box-containing T-cell factor required for thymocyte differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer

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7 January 2021

Autonomous requirements for the segment polarity gene armadillo during Drosophila embryogenesis.

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7 January 2021

Two waves of recombinase gene expression in developing thymocytes

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7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

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https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

The dishevelled protein is modified by wingless signaling in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2899%2900026-8

7 January 2021

10.1016/S0304-419X(99)00026-8

Identifiers

DOI

1 reference

29 July 2017

1 reference