Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells (Q33755491)

29 July 2017

Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells (English)

1 reference

29 July 2017

1 reference

1 reference

6

Jasti S Rao

1 reference

ORCID Public Data File 2021

29 July 2017

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author name string

Hari Raghu

1

1 reference

29 July 2017

Prasanna Kumar Sodadasu

2

1 reference

29 July 2017

Rama Rao Malla

3

1 reference

29 July 2017

Christopher S Gondi

4

1 reference

29 July 2017

Norman Estes

5

1 reference

29 July 2017

language of work or name

English

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publication date

24 November 2010

1 reference

29 July 2017

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29 July 2017

10

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29 July 2017

647

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3002355/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/1471-2407-10-647

0 references

cites work

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SRC family kinases accelerate prolactin receptor internalization, modulating trafficking and signaling in breast cancer cells

21 June 2018

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Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR.

21 June 2018

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Targeting lipid rafts inhibits protein kinase B by disrupting calcium homeostasis and attenuates malignant properties of melanoma cells

21 June 2018

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uPA binding increases UPAR localization to lipid rafts and modifies the receptor microdomain composition

21 June 2018

1 reference

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Lipid raft disruption by cholesterol depletion enhances influenza A virus budding from MDCK cells

21 June 2018

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Lipid raft specific knockdown of SRC family kinase activity inhibits cell adhesion and cell cycle progression of breast cancer cells

21 June 2018

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RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.

21 June 2018

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Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro

21 June 2018

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Cholesterol inhibits MMP-9 expression in human epidermal keratinocytes and HaCaT cells

21 June 2018

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Sesamin, a lignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells

21 June 2018

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Lipid rafts of primary endothelial cells are essential for Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8-induced phosphatidylinositol 3-kinase and RhoA-GTPases critical for microtubule dynamics and nuclear delivery of viral DNA but dis

21 June 2018

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RNA interference-mediated simultaneous down-regulation of urokinase-type plasminogen activator receptor and cathepsin B induces caspase-8-mediated apoptosis in SNB19 human glioma cells

21 June 2018

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SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA.

21 June 2018

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The role of cholesterol in prostate cancer

21 June 2018

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Metastatic potential of mouse Lewis lung cancer cells is regulated via ganglioside GM1 by modulating the matrix metalloprotease-9 localization in lipid rafts.

21 June 2018

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Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents

21 June 2018

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Role of cholesterol and lipid organization in disease

21 June 2018

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Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts

21 June 2018

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Cholesterol and prostate cancer

21 June 2018

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Dimerization controls the lipid raft partitioning of uPAR/CD87 and regulates its biological functions

21 June 2018

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Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors

21 June 2018

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Role of cholesterol in lipid raft formation: lessons from lipid model systems

21 June 2018

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Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.

21 June 2018

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Role of sphingomyelinase and ceramide in modulating rafts: do biophysical properties determine biologic outcome?

21 June 2018

1 reference

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Lipid rafts and little caves. Compartmentalized signalling in membrane microdomains

21 June 2018

1 reference

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Membrane cholesterol, protein phosphorylation, and lipid rafts

21 June 2018

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Down-regulation of integrin alpha(v)beta(3) expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense urokinase-type plasminogen activator receptor (uPAR) and sense p16 genes.

21 June 2018

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MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

21 June 2018

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Matrix metalloproteinases in wound repair (review).

21 June 2018

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Membrane rafts and signaling by the multichain immune recognition receptors

21 June 2018

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Modulation of alpha5beta1 integrin functions by the phospholipid and cholesterol contents of cell membranes

21 June 2018

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Matrix metalloproteinases

21 June 2018

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Matrix-degrading proteinases are shed in membrane vesicles by ovarian cancer cells in vivo and in vitro

21 June 2018

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Functions of lipid rafts in biological membranes

21 June 2018

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Tumor cell contact mediated transcriptional activation of the fibroblast matrix metalloproteinase-9 gene: involvement of multiple transcription factors including Ets and an alternating purine-pyrimidine repeat

21 June 2018

1 reference

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Matrix metalloproteinases in skin

21 June 2018

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Urokinase plasminogen activator and gelatinases are associated with membrane vesicles shed by human HT1080 fibrosarcoma cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002355

Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002355

Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002355

Cholesterol depletion induces anoikis-like apoptosis via FAK down-regulation and caveolae internalization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002355

Role of caveolae and lipid rafts in cancer: workshop summary and future needs

30 October 2018

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Lipid raft compartmentalization of urokinase receptor signaling in human neutrophils

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002355

Biochemical changes in tumor tissues of oral cancer patients.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002355

Inhibition of N-methyl-N-nitrosourea- and 7,12-dimethylbenz[a] anthracene-induced rat mammary tumorigenesis by dietary cholesterol is independent of Ha-Ras mutations.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002355

Amelioration of the metabolic defect in erythropoietic protoporphyria by expression of human ferrochelatase in cultured cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002355

Cholesterol metabolism in the RSH/Smith-Lemli-Opitz syndrome: summary of an NICHD conference.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002355

Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21106094

12 December 2020

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/21106094

12 December 2020

inferred from PubMed ID database lookup

Selective localization of matrix metalloproteinase 9, beta1 integrins, and human lymphocyte antigen class I molecules on membrane vesicles shed by 8701-BC breast carcinoma cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21106094

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/1471-2407-10-647

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference