Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation (Q33761140)

29 July 2017

Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation (English)

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29 July 2017

Guillermo Barreto

3

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author name string

Andrea Schäfer

1

1 reference

29 July 2017

Lars Schomacher

2

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29 July 2017

Gabi Döderlein

4

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29 July 2017

Christof Niehrs

5

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29 July 2017

language of work or name

English

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publication date

19 November 2010

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29 July 2017

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29 July 2017

5

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29 July 2017

11

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29 July 2017

e14060

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Creative Commons Attribution 4.0 International

29 July 2017

start time

19 November 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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GADD45A does not promote DNA demethylation

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Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

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Role of gemcitabine in cancer therapy

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21 June 2018

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Gemcitabine potentiates cisplatin cytotoxicity and inhibits repair of cisplatin-DNA damage in ovarian cancer cell lines

21 June 2018

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Capillary electrophoretic analysis of genomic DNA methylation levels

21 June 2018

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DNA repair mechanisms involved in gemcitabine cytotoxicity and in the interaction between gemcitabine and cisplatin

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Expression of ERCC1 antisense RNA abrogates gemicitabine-mediated cytotoxic synergism with cisplatin in human colon tumor cells defective in mismatch repair but proficient in nucleotide excision repair.

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CpG island methylator phenotypes in aging and cancer.

21 June 2018

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21 June 2018

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21 June 2018

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Base excision DNA repair defect in Gadd45a-deficient cells.

21 June 2018

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Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage

30 October 2018

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Enhancement of DNA ligase I level by gemcitabine in human cancer cells

30 October 2018

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Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage

30 October 2018

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Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism

30 October 2018

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12 December 2020

Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential

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12 December 2020

Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine

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12 December 2020

Action of etoposide (VP-16-123) on human cells: no evidence for topoisomerase II involvement in excision repair of u.v.-induced DNA damage, nor for mitochondrial hypersensitivity in ataxia telangiectasia

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12 December 2020

2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase

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12 December 2020

Action of 2',2'-difluorodeoxycytidine on DNA synthesis

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12 December 2020

Comparison of antineoplastic activity of 2',2'-difluorodeoxycytidine and cytosine arabinoside against human myeloid and lymphoid leukemic cells

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12 December 2020

The fundamental role of epigenetic events in cancer

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12 December 2020

10.1371/JOURNAL.PONE.0014060

Identifiers

DOI

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29 July 2017

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29 July 2017

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