Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak. (Q33767555)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24912196%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak (English)

1 reference

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20 March 2020

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3

1 reference

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20 March 2020

David L Vaux

series ordinal

4

1 reference

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20 March 2020

author name string

Lisa M Lindqvist

series ordinal

1

1 reference

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20 March 2020

Melanie Heinlein

series ordinal

2

1 reference

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20 March 2020

language of work or name

English

0 references

publication date

27 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24912196%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

20 March 2020

published in

1 reference

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20 March 2020

volume

111

1 reference

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20 March 2020

issue

23

1 reference

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20 March 2020

page(s)

8512-8517

1 reference

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To be or not to be? How selective autophagy and cell death govern cell fate

20 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia

14 July 2018

1 reference

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Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor

14 July 2018

1 reference

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Cell death by autophagy: facts and apparent artefacts

14 July 2018

1 reference

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Autophagy and apoptosis: what is the connection?

14 July 2018

1 reference

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BH3 mimetics activate multiple pro-autophagic pathways

14 July 2018

1 reference

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Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

14 July 2018

1 reference

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A systems level strategy for analyzing the cell death network: implication in exploring the apoptosis/autophagy connection.

14 July 2018

1 reference

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Methods in mammalian autophagy research

14 July 2018

1 reference

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Autophagy, not apoptosis, is essential for midgut cell death in Drosophila

14 July 2018

1 reference

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FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

14 July 2018

1 reference

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JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Bcl-2 family members: dual regulators of apoptosis and autophagy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

The BCL-2 protein family: opposing activities that mediate cell death

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Toll-like receptor 4 is a sensor for autophagy associated with innate immunity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Autophagy: dual roles in life and death?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

The pathophysiology of mitochondrial cell death

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060681

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

14 July 2018

1 reference

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Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

14 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1406425111

BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24912196

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1406425111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24912196%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

0 references

1 reference

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20 March 2020

1 reference

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