A novel inhibitor of the NF-{kappa}B signaling pathway encoded by the parapoxvirus orf virus (Q33769300)

29 July 2017

A novel inhibitor of the NF-{kappa}B signaling pathway encoded by the parapoxvirus orf virus (English)

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29 July 2017

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D G Diel

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29 July 2017

G Delhon

2

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29 July 2017

S Luo

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29 July 2017

E F Flores

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29 July 2017

D L Rock

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29 July 2017

10 February 2010

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29 July 2017

84

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3962-3973

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8

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describes a project that uses

29 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2849485/fullTextXML

inferred from PubMed Central ID database lookup

cites work

NFkB inhibitors: strategies from poxviruses

1 reference

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Cowpox virus expresses a novel ankyrin repeat NF-kappaB inhibitor that controls inflammatory cell influx into virus-infected tissues and is critical for virus pathogenesis.

4 July 2018

1 reference

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Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis

4 July 2018

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Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways

4 July 2018

1 reference

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Poxvirus MC160 protein utilizes multiple mechanisms to inhibit NF-kappaB activation mediated via components of the tumor necrosis factor receptor 1 signal transduction pathway.

4 July 2018

1 reference

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Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis

4 July 2018

1 reference

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Ubiquitin-mediated regulation of TNFR1 signaling

4 July 2018

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Inhibition of IkappaB kinase by vaccinia virus virulence factor B14

4 July 2018

1 reference

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Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes

4 July 2018

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Signaling to NF-kappaB by Toll-like receptors

4 July 2018

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The interplay between viruses and innate immune signaling: recent insights and therapeutic opportunities

4 July 2018

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A novel Bcl-2-like inhibitor of apoptosis is encoded by the parapoxvirus ORF virus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Roles of NF-kappaB and MAPK signaling pathways in morphological and cytoskeletal responses of microglia to double-stranded RNA.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Integrating cell-signalling pathways with NF-kappaB and IKK function

4 July 2018

1 reference

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Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses

4 July 2018

1 reference

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Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway

4 July 2018

1 reference

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IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Poxviral regulation of the host NF-kappaB response: the vaccinia virus M2L protein inhibits induction of NF-kappaB activation via an ERK2 pathway in virus-infected human embryonic kidney cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Recognition of vaccinia virus-infected cells by human natural killer cells depends on natural cytotoxicity receptors

4 July 2018

1 reference

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Real-time PCR for mRNA quantitation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

The MCV MC159 protein inhibits late, but not early, events of TNF-α-induced NF-κB activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding [...]

4 July 2018

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Immunomodulatory effects of inactivated parapoxvirus ovis (ORF virus) on human peripheral immune cells: induction of cytokine secretion in monocytes and Th1-like cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Shaping the nuclear action of NF-kappaB

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

The vaccinia virus K1L gene product inhibits host NF-kappaB activation by preventing IkappaBalpha degradation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

A virulence factor of myxoma virus colocalizes with NF-kappaB in the nucleus and interferes with inflammation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

affy--analysis of Affymetrix GeneChip data at the probe level

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Genomes of the parapoxviruses ORF virus and bovine papular stomatitis virus

4 July 2018

1 reference

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Upstream Signal Transduction of NF-&#954;B Activation

4 July 2018

1 reference

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NF-kappaB and virus infection: who controls whom

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Immunity and counter-immunity during infection with the parapoxvirus orf virus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Evidence for a parapox ovis virus-associated superantigen

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Sequence and functional analysis of a homolog of interleukin-10 encoded by the parapoxvirus orf virus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Poxvirus-induced immunostimulating effects on porcine leukocytes.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Activators and target genes of Rel/NF-kappaB transcription factors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

An epidemic of parapoxvirus infection among cattle: isolation and antibody survey

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Natural transmission of orf virus from clinically normal ewes to orf-naive sheep

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Principles of paramunization. Option and limits in veterinary medicine

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Studies of the pathogenesis of orf virus infection in sheep

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Detection of contagious pustular dermatitis virus of goats in a severe outbreak

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Experimental detection of the paraspecific effects of purified and inactivated poxviruses

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Generalized contagious ecthyma in a sheep rancher: diagnostic considerations

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Induction of spindle cell morphology in human vascular endothelial cells by human herpesvirus 8-encoded viral FLICE inhibitory protein K13.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Stochastic models inspired by hybridization theory for short oligonucleotide arrays.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Severe Persistent Orf in Young Goats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Characterization of a North American orf virus isolated from a goat with persistent, proliferative dermatitis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Construction of a novel set of transfer vectors to study vaccinia virus replication and foreign gene expression

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Human orf and erythema multiforme

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Immune response of lambs to experimental infection with Orf virus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849485

Orf. A case report with histologic, electron microscopic, and immunoperoxidase studies

30 October 2018

1 reference

12 December 2020

Chronic contagious ecthyma and caseous lymphadenitis in two Boer goats

1 reference

12 December 2020

The use of a non-specific defence mechanism inducer in calves exposed to bovine herpesvirus-1 infection: preliminary trials

1 reference

12 December 2020

The use of Baypamun N in crowding associated infectious respiratory disease: efficacy of Baypamun N (freeze dried product) in 4-10 month old horses

1 reference

12 December 2020

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

1 reference

12 December 2020

Isolation of parapoxvirus from a cow treated with interferon-gamma

1 reference

12 December 2020

Persistent parapoxvirus infection in cattle

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.02291-09

1 reference

29 July 2017

1 reference

29 July 2017

1 reference