Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance (Q33772290)

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English	Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance	scientific article

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scholarly article

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PubMed publication ID

29 July 2017

Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance (English)

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29 July 2017

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insulin resistance

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author name string

D Weismann

1

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29 July 2017

D M Erion

2

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29 July 2017

I Ignatova-Todorava

3

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29 July 2017

Y Nagai

4

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29 July 2017

R Stark

5

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29 July 2017

J J Hsiao

6

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29 July 2017

C Flannery

7

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29 July 2017

A L Birkenfeld

8

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29 July 2017

T May

9

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29 July 2017

M Kahn

10

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29 July 2017

D Zhang

11

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29 July 2017

X X Yu

12

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29 July 2017

S F Murray

13

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29 July 2017

S Bhanot

14

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29 July 2017

B P Monia

15

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29 July 2017

G W Cline

16

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29 July 2017

G I Shulman

17

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29 July 2017

V T Samuel

18

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29 July 2017

publication date

29 December 2010

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29 July 2017

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29 July 2017

54

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29 July 2017

4

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29 July 2017

935-944

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29 July 2017

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4061906/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Mammalian Tribbles homolog 3 impairs insulin action in skeletal muscle: role in glucose-induced insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Insulin regulates TRB3 and other stress-responsive gene expression through induction of C/EBPbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Fat and beyond: the diverse biology of PPARgamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

PI3K activates negative and positive signals to regulate TRB3 expression in hepatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

TRB3 suppresses adipocyte differentiation by negatively regulating PPARgamma transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

TRB3 blocks adipocyte differentiation through the inhibition of C/EBPbeta transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

TRB3 modulates C2C12 differentiation by interfering with Akt activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Effect of TRB3 on insulin and nutrient-stimulated hepatic p70 S6 kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

1 reference

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28 July 2018

Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

The transcriptional basis of adipocyte development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Lack of evidence for a role of TRB3/NIPK as an inhibitor of PKB-mediated insulin signalling in primary hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061906

28 July 2018

In vivo distribution and metabolism of a phosphorothioate oligonucleotide within rat liver after intravenous administration.

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28 July 2018

Cellular mechanisms of insulin resistance

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https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

Critical nodes in signalling pathways: insights into insulin action

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

Overexpression of TRB3 gene in adipose tissue of rats with high fructose-induced metabolic syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

Association of TRB3 gene Q84R polymorphism with type 2 diabetes mellitus in Chinese population

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

Genetic deletion of Trb3, the mammalian Drosophila tribbles homolog, displays normal hepatic insulin signaling and glucose homeostasis.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

A new mathematical model for relative quantification in real-time RT-PCR

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https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

Role of adiponectin in human skeletal muscle bioenergetics

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https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice.

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https://api.crossref.org/works/10.1007%2FS00125-010-1984-5

21 January 2018

Regulation of Akt/PKB activation by tyrosine phosphorylation

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21 January 2018

Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients

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21 January 2018

TRIB3 R84 Variant Is Associated With Impaired Insulin-Mediated Nitric Oxide Production in Human Endothelial Cells

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https://pubmed.ncbi.nlm.nih.gov/21190014

12 December 2020

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Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin

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https://pubmed.ncbi.nlm.nih.gov/21190014

12 December 2020

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Effect of AMPK activation on muscle glucose metabolism in conscious rats

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https://pubmed.ncbi.nlm.nih.gov/21190014

12 December 2020

based on heuristic

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Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21190014

12 December 2020

based on heuristic

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10.1007/S00125-010-1984-5

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Europe PubMed Central

PubMed publication ID

29 July 2017

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Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

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Europe PubMed Central

PubMed publication ID

29 July 2017

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