Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity. (Q33772507)

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English	Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity.	scientific article

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5 February 2020

Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity (English)

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Bernard A Fox

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Ulf Petrausch

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Christopher Twitty

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Christian H Poehlein

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Daniel P Haley

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Edwin B Walker

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19 August 2009

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8

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Journal of Immunology

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3682-3689

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5 February 2020

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The critical contribution of TGF-beta to the induction of Foxp3 expression and regulatory T cell function

1 reference

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

1 reference

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Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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In vivo instruction of suppressor commitment in naive T cells

1 reference

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IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

1 reference

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4 July 2018

Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

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30 October 2018

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30 October 2018

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1 reference

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19692636

12 December 2020

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Elevated serum levels of transforming growth factor-beta1 in patients with colorectal carcinoma: its association with tumor progression and its significant decrease after curative surgical resection

1 reference

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12 December 2020

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Inducing and expanding regulatory T cell populations by foreign antigen

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Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer

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12 December 2020

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inferred from PubMed ID database lookup

Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

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1 reference

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12 December 2020

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1 reference

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10.4049/JIMMUNOL.0900560

1 reference

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5 February 2020

1 reference

Europe PubMed Central

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5 February 2020

1 reference

Europe PubMed Central

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5 February 2020

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