The cyclooxygenase isoforms: structural insights into the conversion of arachidonic acid to prostaglandins (Q33778070)

29 July 2017

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title

The cyclooxygenase isoforms: structural insights into the conversion of arachidonic acid to prostaglandins (English)

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29 July 2017

R M Garavito

1

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PubMed ID

10570255

29 July 2017

D L DeWitt

series ordinal

2

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PubMed ID

10570255

29 July 2017

language of work or name

English

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publication date

1 November 1999

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Biochimica et Biophysica Acta

29 July 2017

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29 July 2017

1441

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29 July 2017

2-3

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29 July 2017

278-287

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Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Identification of a phorbol ester-repressible v-src-inducible gene

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Prostaglandin synthase 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

X-ray crystal structure of canine myeloperoxidase at 3 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Prostaglandin H synthase: implications for membrane structure.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

The membrane association sequences of the prostaglandin endoperoxide synthases-1 and -2 isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Epidermal growth factor-like modules

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Arginine 120 of prostaglandin G/H synthase-1 is required for the inhibition by nonsteroidal anti-inflammatory drugs containing a carboxylic acid moiety

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2. Formation of 12-hydroxy-(9Z, 13E/Z, 15Z)- octadecatrienoic acids from alpha-linolenic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Comparison of hydroperoxide initiator requirements for the cyclooxygenase activities of prostaglandin H synthase-1 and -2.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

The role of arginine 120 of human prostaglandin endoperoxide H synthase-2 in the interaction with fatty acid substrates and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Conversion of prostaglandin G/H synthase-1 into an enzyme sensitive to PGHS-2-selective inhibitors by a double His513 --> Arg and Ile523 --> val mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Colorectal cancer and nonsteroidal anti-inflammatory drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Aspirin and the Risk of Colorectal Cancer in Women

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Aspirin as prophylaxis against colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

The Use of Aspirin in Ischemic Heart Disease

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900147-X

7 January 2021

10.1016/S1388-1981(99)00147-X

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10570255