Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis (Q33779516)

29 July 2017

title

Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis (English)

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29 July 2017

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Yannan Jiang

1

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29 July 2017

Xinming Qi

2

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29 July 2017

Xinyu Liu

3

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29 July 2017

Jun Zhang

4

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29 July 2017

Jun Ji

5

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29 July 2017

Zhenggang Zhu

6

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29 July 2017

Jin Ren

7

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29 July 2017

Yingyan Yu

8

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29 July 2017

language of work or name

English

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publication date

3 April 2017

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29 July 2017

number of pages

13

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based on heuristic

inferred from page(s)

published in

Oncotarget

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29 July 2017

volume

8

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29 July 2017

issue

20

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29 July 2017

page(s)

33444-33456

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Transgenic and gene knockout mice in gastric cancer research

29 July 2017

cites work

1 reference

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Mutational analysis of the hCDC4 gene in gastric carcinomas

28 July 2018

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Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability

28 July 2018

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Inactivation of hCDC4 can cause chromosomal instability

28 July 2018

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Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

28 July 2018

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H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities

30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.

30 October 2018

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Loss of CDC4/FBXW7 in gastric carcinoma.

30 October 2018

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p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases

30 October 2018

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FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

Principles of tumor suppression

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

Cadmium inhibits repair of UV-, methyl methanesulfonate- and N-methyl-N-nitrosourea-induced DNA damage in Chinese hamster ovary cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

Independent variation in susceptibilities of six different mouse strains to induction of pepsinogen-altered pyloric glands and gastric tumor intestinalization by N-methyl-N-nitrosourea

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464881

Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28422719

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.16800

1 reference

release_zmy4f45j65dyzem26tlskft3oa

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zmy4f45j65dyzem26tlskft3oa

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

5464881

1 reference

29 July 2017

1 reference