Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling (Q33782491)

29 July 2017

Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling (English)

1 reference

29 July 2017

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Yifan Zhan

3

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Philippe Bouillet

Philippe Bouillet

6

0 references

Andrew M Lew

Andrew M Lew

5

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Dale I Godfrey

Dale I Godfrey

8

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William R Heath

William R Heath

9

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Andreas Strasser

Andreas Strasser

10

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author name string

Andreas Villunger

1

1 reference

29 July 2017

Vanessa S Marsden

2

1 reference

29 July 2017

Miriam Erlacher

4

1 reference

29 July 2017

Stuart Berzins

7

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29 July 2017

language of work or name

English

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publication date

26 April 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

1 reference

29 July 2017

101

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29 July 2017

18

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29 July 2017

7052-7057

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Normal thymocyte negative selection in TRAIL-deficient mice

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Mechanisms of caspase activation and inhibition during apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

The expanding role of mitochondria in apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

BH3-Only proteins-essential initiators of apoptotic cell death

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

A role for Fas in negative selection of thymocytes in vivo

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Bim: a novel member of the Bcl-2 family that promotes apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Bcl-2 expression promotes B- but not T-lymphoid development in scid mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406464

Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

4 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0305757101

The apoptotic protease-activating factor 1-mediated pathway of apoptosis is dispensable for negative selection of thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0305757101

Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0305757101

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0305757101

T-cell apoptosis detected in situ during positive and negative selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0305757101

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0305757101

Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0305757101

A defect in central tolerance in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0305757101

21 January 2018

Identifiers

DOI

10.1073/PNAS.0305757101

1 reference

29 July 2017

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1 reference

29 July 2017

1 reference