Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress (Q33786940)

29 July 2017

Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress (English)

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29 July 2017

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endoplasmic reticulum

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Ricardo Armisén

3

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author name string

Mauricio Torres

1

1 reference

29 July 2017

Karen Castillo

2

1 reference

29 July 2017

Andrés Stutzin

4

1 reference

29 July 2017

Claudio Soto

5

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29 July 2017

Claudio Hetz

6

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29 July 2017

language of work or name

English

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publication date

29 December 2010

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29 July 2017

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29 July 2017

5

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29 July 2017

12

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29 July 2017

e15658

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Creative Commons Attribution 4.0 International

29 July 2017

start time

29 December 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3012133/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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4 July 2018

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BI-1 regulates endoplasmic reticulum Ca2+ homeostasis downstream of Bcl-2 family proteins

4 July 2018

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Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis.

4 July 2018

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Involvement of mitochondria in endoplasmic reticulum stress-induced apoptotic cell death pathway triggered by the prion peptide PrP(106-126).

4 July 2018

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Activation of H2O2-induced VSOR Cl- currents in HTC cells require phospholipase Cgamma1 phosphorylation and Ca2+ mobilisation

4 July 2018

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Mutant prion protein D202N associated with familial prion disease is retained in the endoplasmic reticulum and forms 'curly' intracellular aggregates

4 July 2018

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Disease-associated prion protein oligomers inhibit the 26S proteasome

4 July 2018

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Perturbation of endoplasmic reticulum homeostasis facilitates prion replication.

4 July 2018

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4 July 2018

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Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein

4 July 2018

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Molecular morphology and toxicity of cytoplasmic prion protein aggregates in neuronal and non-neuronal cells

4 July 2018

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Stressing out the ER: a role of the unfolded protein response in prion-related disorders

4 July 2018

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4 July 2018

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The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

4 July 2018

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Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

4 July 2018

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Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

4 July 2018

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Prion protein trafficking and the development of neurodegeneration

4 July 2018

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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

4 July 2018

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Protein misfolding and disease: the case of prion disorders

4 July 2018

1 reference

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Ca2+ signaling and calcium binding chaperones of the endoplasmic reticulum

4 July 2018

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The endoplasmic reticulum: a multifunctional signaling organelle

4 July 2018

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Overexpressed protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob disease

4 July 2018

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Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release

4 July 2018

1 reference

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Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

4 July 2018

1 reference

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Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

4 July 2018

1 reference

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Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Mutant prion proteins are partially retained in the endoplasmic reticulum

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic Reticulum.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Prions: disease propagation and disease therapy by conformational transmission

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Cultured cell sublines highly susceptible to prion infection

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Cellular biology of prion diseases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Intracellular calcium rise through L-type calcium channels, as molecular mechanism for prion protein fragment 106-126-induced astroglial proliferation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012133

Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

4 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

A Transmembrane Form of the Prion Protein Is Localized in the Golgi Apparatus of Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

Stimulation of PrP(C) retrograde transport toward the endoplasmic reticulum increases accumulation of PrP(Sc) in prion-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

Gene expression profiling of the preclinical scrapie-infected hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

Prion pathogenesis is independent of caspase-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

A mutation in serca underlies motility dysfunction in accordion zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015658

Prion Protein Aggregation Reverted by Low Temperature in Transfected Cells Carrying a Prion Protein Gene Mutation

21 January 2018

1 reference

12 December 2020

Proteasomal Degradation and N-terminal Protease Resistance of the Codon 145 Mutant Prion Protein

1 reference

12 December 2020

Cellular tolerance of prion protein PrP in yeast involves proteolysis and the unfolded protein response

1 reference

12 December 2020

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

1 reference

12 December 2020

Apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126

1 reference

12 December 2020

The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0015658

Identifiers

DOI

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29 July 2017

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29 July 2017

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