Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release (Q40734071)

23 September 2017

Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release (English)

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23 September 2017

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Mathieu Marella

1

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23 September 2017

Sylvain Lehmann

series ordinal

2

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23 September 2017

Jacques Grassi

series ordinal

3

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23 September 2017

Joëlle Chabry

series ordinal

4

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23 September 2017

language of work or name

English

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publication date

6 May 2002

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

25457-25464

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23 September 2017

28

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Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

A cellular gene encodes scrapie PrP 27-30 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Functionally different GPI proteins are organized in different domains on the neuronal surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Endocytosis of simian virus 40 into the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Bound simian virus 40 translocates to caveolin-enriched membrane domains, and its entry is inhibited by drugs that selectively disrupt caveolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Trafficking of the cellular isoform of the prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Amphotericin B inhibits the generation of the scrapie isoform of the prion protein in infected cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

The cellular prion protein binds copper in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Copper stimulates endocytosis of the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Caveolin, a protein component of caveolae membrane coats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Cationic amphiphilic drugs inhibit the internalization of cholera toxin to the Golgi apparatus and the subsequent elevation of cyclic AMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Truncated forms of the human prion protein in normal brain and in prion diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Surface distribution and recycling of the low density lipoprotein receptor as visualized with antireceptor antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Transport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Prion protein selectively binds copper(II) ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Location and properties of metal-binding sites on the human prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Nerve endings from rat brain tissue release copper upon depolarization. A possible role in regulating neuronal excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Prion and prejudice: normal protein and the synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Inhibition of scrapie-associated PrP accumulation. Probing the role of glycosaminoglycans in amyloidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Sulfated glycans stimulate endocytosis of the cellular isoform of the prion protein, PrPC, in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

The effects of the polyene antibiotics nystatin and amphotericin B on thin lipid membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203248200

21 January 2018

Identifiers

DOI

10.1074/JBC.M203248200

1 reference

23 September 2017

1 reference