Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway (Q33787400)

29 July 2017

title

Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway (English)

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29 July 2017

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7

Bharat B Aggarwal

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29 July 2017

5

Bokyung Sung

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29 July 2017

Xiufeng Pang

1

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29 July 2017

Zhengfang Yi

2

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29 July 2017

Jing Zhang

3

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29 July 2017

Binbin Lu

4

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29 July 2017

Weijing Qu

6

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29 July 2017

Mingyao Liu

8

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29 July 2017

language of work or name

English

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publication date

16 February 2010

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29 July 2017

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29 July 2017

volume

70

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29 July 2017

issue

5

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29 July 2017

page(s)

1951-1959

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Acetyl-11-keto-beta-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis

29 July 2017

cites work

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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The role of mTOR in the management of solid tumors: an overview

4 July 2018

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Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

4 July 2018

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Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression

4 July 2018

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Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling.

4 July 2018

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A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

4 July 2018

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Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule.

4 July 2018

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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

4 July 2018

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Molecular understanding and modern application of traditional medicines: triumphs and trials.

4 July 2018

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IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

4 July 2018

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Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation

4 July 2018

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Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

4 July 2018

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Tripterine inhibits the expression of adhesion molecules in activated endothelial cells.

4 July 2018

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Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854134

Chronic inhibition of cardiac Kir2.1 and HERG potassium channels by celastrol with dual effects on both ion conductivity and protein trafficking.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854134

Vascular endothelial growth factor contributes to prostate cancer-mediated osteoblastic activity

4 July 2018

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The Akt-mTOR tango and its relevance to cancer

4 July 2018

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Dysregulation of the TSC-mTOR pathway in human disease

4 July 2018

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Celastrols as inducers of the heat shock response and cytoprotection.

4 July 2018

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Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration

4 July 2018

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Role of the p70(S6K) pathway in regulating the actin cytoskeleton and cell migration

4 July 2018

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PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854134

Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease

4 July 2018

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Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis.

4 July 2018

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Therapeutic effect of tripterine on adjuvant arthritis in rats

30 October 2018

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Capsiate, a nonpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity.

30 October 2018

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Beneficial effect of tripterine on systemic lupus erythematosus induced by active chromatin in BALB/c mice

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854134

Apoptosis Induction in HL-60 Cells and Inhibition of Topoisomerase II by Triterpene Celastrol

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854134

A phase I study of ethyl acetate extract of the chinese antirheumatic herb Tripterygium wilfordii hook F in rheumatoid arthritis.

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854134

Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20160026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Celastrol blocks neuronal cell death and extends life in transgenic mouse model of amyotrophic lateral sclerosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20160026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[Tripterine inhibits all-trans retinoic acid-caused adhesion between leukemia cells and endothelial cells]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20160026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-09-3201

1 reference

29 July 2017

1 reference

29 July 2017

1 reference