Targeted disruption of Bcl-xL in mouse keratinocytes inhibits both UVB- and chemically induced skin carcinogenesis. (Q33788745)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19309000%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Targeted disruption of Bcl-xL in mouse keratinocytes inhibits both UVB- and chemically induced skin carcinogenesis (English)

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24 January 2020

1 reference

1 reference

1

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24 January 2020

author name string

Ken Kataoka

2

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24 January 2020

Shigetoshi Sano

3

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24 January 2020

Kevin Connolly

4

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24 January 2020

Kaoru Kiguchi

5

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24 January 2020

John DiGiovanni

6

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24 January 2020

publication date

1 October 2009

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24 January 2020

published in

Molecular Carcinogenesis

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24 January 2020

volume

48

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24 January 2020

page(s)

873-885

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24 January 2020

issue

10

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Constitutive activation and targeted disruption of signal transducer and activator of transcription 3 (Stat3) in mouse epidermis reveal its critical role in UVB-induced skin carcinogenesis.

24 January 2020

cites work

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Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis

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Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis

4 July 2018

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4 July 2018

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Targeting Bcl-X(L) for prevention and therapy of skin cancer

4 July 2018

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Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency

4 July 2018

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The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells

4 July 2018

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Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells

4 July 2018

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Stat3 regulates genes common to both wound healing and cancer

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UVB-induced apoptosis drives clonal expansion during skin tumor development

4 July 2018

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Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis

4 July 2018

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Cell death: critical control points

4 July 2018

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In vivo cooperation between Bcl-xL and the phosphoinositide 3-kinase-Akt signaling pathway for the protection of epidermal keratinocytes from apoptosis.

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Regulation of Bcl-xL: a little bit of this and a little bit of STAT.

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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The biology of the (6-4) photoproduct

4 July 2018

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Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

4 July 2018

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Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer

4 July 2018

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Signal transducer and activator of transcription 3 is a key regulator of keratinocyte survival and proliferation following UV irradiation.

4 July 2018

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Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression.

30 October 2018

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A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas.

30 October 2018

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Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.

30 October 2018

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Bcl-x expression influences keratinocyte cell survival but not terminal differentiation

30 October 2018

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12 December 2020

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[1] Isolation and utilization of epidermal keratinocytes for oncogene research

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12 December 2020

Identifiers

DOI

10.1002/MC.20527

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19309000%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19309000%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference