Cell death: critical control points (Q28240722)

cysteine-type endopeptidase regulator activity involved in apoptotic process

Europe PubMed Central

title

Cell death: critical control points (English)

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main subject

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cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Gene Ontology ID

GO:0043028

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activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

Gene Ontology ID

GO:0043027

1 reference

activation of cysteine-type endopeptidase activity involved in apoptotic process

Gene Ontology ID

GO:0008635

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Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

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2

Stanley J Korsmeyer

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author name string

Nika N Danial

series ordinal

1

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language of work or name

English

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publication date

23 January 2004

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published in

Cell

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volume

116

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page(s)

205-19

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issue

2

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cites work

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Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

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Mitochondria and cell death. Mechanistic aspects and methodological issues

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Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans.

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The Drosophila bcl-2 family member dBorg-1 functions in the apoptotic response to UV-irradiation

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bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

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Structural and biochemical basis of apoptotic activation by Smac/DIABLO

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Structural basis of caspase-7 inhibition by XIAP

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grim, a novel cell death gene in Drosophila

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p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

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Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death.

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

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VDAC2 inhibits BAK activation and mitochondrial apoptosis

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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

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Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

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Prevention of apoptosis by a baculovirus gene during infection of insect cells

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The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

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BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

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7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

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Exogenous smac induces competence and permits caspase activation in sympathetic neurons.

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7 January 2021

X-linked IAP is a direct inhibitor of cell-death proteases

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7 January 2021

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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Genetic control of programmed cell death in the nematode C. elegans.

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

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A receptor for phosphatidylserine-specific clearance of apoptotic cells

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7 January 2021

Insights into programmed cell death through structural biology

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7 January 2021

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

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7 January 2021

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

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7 January 2021

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

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7 January 2021

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

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7 January 2021

Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

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7 January 2021

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration

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ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine

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7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

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7 January 2021

Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

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7 January 2021

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

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Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

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7 January 2021

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

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7 January 2021

Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans

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7 January 2021

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

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7 January 2021

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

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7 January 2021

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

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7 January 2021

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

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7 January 2021

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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7 January 2021

Autophagy as a regulated pathway of cellular degradation

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7 January 2021

Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks

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7 January 2021

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

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7 January 2021

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

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7 January 2021

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

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7 January 2021

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

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7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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7 January 2021

Endonuclease G is an apoptotic DNase when released from mitochondria

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7 January 2021

Induction of autophagy and inhibition of tumorigenesis by beclin 1

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7 January 2021

The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

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7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

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7 January 2021

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

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7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

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7 January 2021

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

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7 January 2021

PROGRAMMED CELL DEATH--I. CYTOLOGY OF DEGENERATION IN THE INTERSEGMENTAL MUSCLES OF THE PERNYI SILKMOTH.

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7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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7 January 2021

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

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7 January 2021

Apoptosis in neurodegenerative disorders

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7 January 2021

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

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7 January 2021

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

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7 January 2021

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

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7 January 2021

p53 has a direct apoptogenic role at the mitochondria

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7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

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7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

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7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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7 January 2021

PUMA, a novel proapoptotic gene, is induced by p53

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7 January 2021

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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7 January 2021

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

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7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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7 January 2021

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

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7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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7 January 2021

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

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7 January 2021

Cytochrome c release from mitochondria proceeds by a two-step process

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7 January 2021

Mitochondrial endonuclease G is important for apoptosis in C. elegans.

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7 January 2021

Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells.

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7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

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7 January 2021

Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions

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7 January 2021

Social controls on cell survival and cell death

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7 January 2021

CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

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7 January 2021

Phagocytosis promotes programmed cell death in C. elegans.

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7 January 2021

Structural basis for the inhibition of caspase-3 by XIAP

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7 January 2021

Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1.

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7 January 2021

IAP proteins: blocking the road to death's door

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7 January 2021

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

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7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

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7 January 2021

Corpse clearance defines the meaning of cell death

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7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

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7 January 2021

A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

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7 January 2021

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

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7 January 2021

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities

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7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

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7 January 2021

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

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7 January 2021

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

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7 January 2021

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

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7 January 2021

Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP)

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7 January 2021

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

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7 January 2021

Post-embryonic development in the ventral cord of Caenorhabditis elegans

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7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

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https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

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7 January 2021

Structure of Bax: coregulation of dimer formation and intracellular localization

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7 January 2021

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

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7 January 2021

A novel domain within the 55 kd TNF receptor signals cell death

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7 January 2021

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

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7 January 2021

Caspases: enemies within

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7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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7 January 2021

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

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7 January 2021

Involvement of the bcl-2 gene in human follicular lymphoma

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7 January 2021

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

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7 January 2021

Growth factors can influence cell growth and survival through effects on glucose metabolism

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7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

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7 January 2021

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

BID: a novel BH3 domain-only death agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Genetic control of programmed cell death in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Regulated nuclear import of Rel proteins in the Drosophila immune response.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

PUMA induces the rapid apoptosis of colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2804%2900046-7

7 January 2021

10.1016/S0092-8674(04)00046-7

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

release_pyrcy3lnkvg3zpzfw3rlublcwq

380053

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pyrcy3lnkvg3zpzfw3rlublcwq

24 November 2022

mapped directly with Wikidata item

380053

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference