11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess (Q33789944)

29 July 2017

11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess (English)

1 reference

29 July 2017

7

Paul M Stewart

0 references

Jeremy W Tomlinson

object named as

Jeremy W Tomlinson

8

0 references

author name string

Stuart A Morgan

1

1 reference

29 July 2017

Emma L McCabe

2

1 reference

29 July 2017

Laura L Gathercole

3

1 reference

29 July 2017

Zaki K Hassan-Smith

4

1 reference

29 July 2017

Dean P Larner

5

1 reference

29 July 2017

Iwona J Bujalska

6

1 reference

29 July 2017

Gareth G Lavery

9

1 reference

29 July 2017

language of work or name

English

0 references

publication date

2 June 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

1 reference

29 July 2017

111

1 reference

29 July 2017

E2482-91

1 reference

29 July 2017

24

1 reference

describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4066483/fullTextXML

inferred from PubMed Central ID database lookup

cites work

11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Risk of cardiovascular events in people prescribed glucocorticoids with iatrogenic Cushing's syndrome: cohort study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

5α-reduced glucocorticoids exhibit dissociated anti-inflammatory and metabolic effects.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Hexose-6-phosphate dehydrogenase contributes to skeletal muscle homeostasis independent of 11β-hydroxysteroid dehydrogenase type 1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

The 11-beta-hydroxysteroid dehydrogenase type 1 inhibitor INCB13739 improves hyperglycemia in patients with type 2 diabetes inadequately controlled by metformin monotherapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Endocrine and physiological changes in response to chronic corticosterone: a potential model of the metabolic syndrome in mouse

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

BOL-303242-X, a novel selective glucocorticoid receptor agonist, with full anti-inflammatory properties in human ocular cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Direct effect of glucocorticoids on lipolysis in adipocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

trans-Activation and repression properties of the novel nonsteroid glucocorticoid receptor ligand 2,5-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5-(1-methylcyclohexen-3-y1)-1H-[1]benzopyrano[3,4-f]quinoline (A276575) and its four stereoisomers

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Osteoblastic 11beta-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

A transgenic model of visceral obesity and the metabolic syndrome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

Use of oral corticosteroids in the United Kingdom

4 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1323681111

Prevalence of oral glucocorticoid usage in the United States: a general population perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1323681111

Taking glucocorticoids by prescription is associated with subsequent cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1323681111

Outcome of Cushing's disease following transsphenoidal surgery in a single center over 20 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1323681111

Effects of an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, MK-0916, in patients with type 2 diabetes mellitus and metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1323681111

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1323681111

Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: the Hertfordshire Cohort Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1323681111

Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1323681111

11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1323681111

Absence of Cushingoid phenotype in a patient with Cushing's disease due to defective cortisone to cortisol conversion

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066483

11-Dehydrocorticosterone Causes Metabolic Syndrome, Which Is Prevented when 11β-HSD1 Is Knocked Out in Livers of Male Mice

30 October 2018

1 reference

12 December 2020

Kinetics and Interconversion of Prednisolone and Prednisone Studied with New Radioimmunoassays

1 reference

12 December 2020

Urinary free cortisol and cortisone determined by high performance liquid chromatography in the diagnosis of Cushing's syndrome

1 reference

12 December 2020

Corticosteroid-induced clinical adverse events: frequency, risk factors and patient's opinion

1 reference

12 December 2020

Localization, Age- and Site-Dependent Expression, and Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 in Skin

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1323681111

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference