Targeted therapy for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus. (Q33793543)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17762570%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

review article

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title

Targeted therapy for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17762570%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17762570%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Susan E Krown

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17762570%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

publication date

1 September 2007

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17762570%20AND%20SRC:MED&resulttype=core&format=json

Current Opinion in Oncology

4 January 2020

published in

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4 January 2020

volume

19

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4 January 2020

page(s)

452-457

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4 January 2020

issue

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17762570%20AND%20SRC:MED&resulttype=core&format=json

Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expression

4 January 2020

cites work

1 reference

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HIV protease inhibitor nelfinavir inhibits growth of human melanoma cells by induction of cell cycle arrest

4 July 2018

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Inhibition of NF-kappaB activation in vivo impairs establishment of gammaherpesvirus latency

4 July 2018

1 reference

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

4 July 2018

1 reference

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Restoration of p53 function leads to tumour regression in vivo

4 July 2018

1 reference

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Modeling the therapeutic efficacy of p53 restoration in tumors

4 July 2018

1 reference

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Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy.

4 July 2018

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Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling

4 July 2018

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Reactivation of Kaposi's sarcoma-associated herpesvirus by natural products from Kaposi's sarcoma endemic regions

4 July 2018

1 reference

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Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin

4 July 2018

1 reference

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The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Trends in cancer risk among people with AIDS in the United States 1980-2002.

4 July 2018

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Post-transplant de novo malignancies in renal transplant recipients: the past and present

4 July 2018

1 reference

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Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics

4 July 2018

1 reference

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Cyclin-dependent kinase activity is required for efficient expression and posttranslational modification of human cytomegalovirus proteins and for production of extracellular particles

4 July 2018

1 reference

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Loss of p53 impedes the antileukemic response to BCR-ABL inhibition

4 July 2018

1 reference

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Evaluation of antitumoral properties of the protease inhibitor indinavir in a murine model of hepatocarcinoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Remission from Kaposi's sarcoma on HAART is associated with suppression of HIV replication and is independent of protease inhibitor therapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer

4 July 2018

1 reference

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Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

The global health burden of infection-associated cancers in the year 2002

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Interferon-alpha2b with protease inhibitor-based antiretroviral therapy in patients with AIDS-associated Kaposi sarcoma: an AIDS malignancy consortium phase I trial

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

KSHV G protein-coupled receptor inhibits lytic gene transcription in primary-effusion lymphoma cells via p21-mediated inhibition of Cdk2.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Sirolimus for Kaposi's sarcoma in renal-transplant recipients

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Use of liposomal anthracyclines in Kaposi's sarcoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Roscovitine, a cyclin-dependent kinase inhibitor, prevents replication of varicella-zoster virus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Expression of p53 and human herpesvirus-8 (HHV-8)-encoded latency-associated nuclear antigen with inhibition of apoptosis in HHV-8-associated malignancies

4 July 2018

1 reference

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Viral cyclin-cyclin-dependent kinase 6 complexes initiate nuclear DNA replication

4 July 2018

1 reference

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Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Inhibition of cellular Cdk2 activity blocks human cytomegalovirus replication

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Matrix metalloproteinases in the progression and regression of Kaposi's sarcoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Immortalization of primary endothelial cells by the K1 protein of Kaposi's sarcoma-associated herpesvirus.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Capacity building for the clinical investigation of AIDS malignancy in East Africa.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Imatinib-induced regression of AIDS-related Kaposi's sarcoma

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma–associated herpesvirus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855645

Histone deacetylase inhibitors induce apoptosis with minimal viral reactivation in cells infected with Kaposi's sarcoma-associated herpesvirus

30 October 2018

1 reference

12 December 2020

Angiogenesis Inhibitor IM862 Is Ineffective Against AIDS-Kaposi's Sarcoma in a Phase III Trial, but Demonstrates Sustained, Potent Effect of Highly Active Antiretroviral Therapy: From the AIDS Malignancy Consortium and IM862 Study Team

1 reference

12 December 2020

Randomized phase II trial of matrix metalloproteinase inhibitor COL-3 in AIDS-related Kaposi's sarcoma: an AIDS Malignancy Consortium Study

1 reference

12 December 2020

Sirolimus conversion for patients with posttransplant Kaposi's sarcoma

1 reference

12 December 2020

10.1097/CCO.0B013E3281EB8EA7

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17762570%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17762570%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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