Lysosome dysfunction triggers Atg7-dependent neural apoptosis (Q33796094)

29 July 2017

Lysosome dysfunction triggers Atg7-dependent neural apoptosis (English)

1 reference

29 July 2017

1 reference

Mary Ballestas

5

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Kevin A. Roth

object named as

Kevin A Roth

8

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author name string

Ken C Walls

1

1 reference

29 July 2017

Arindam P Ghosh

2

1 reference

29 July 2017

Aimee V Franklin

3

1 reference

29 July 2017

Barbara J Klocke

4

1 reference

29 July 2017

John J Shacka

6

1 reference

29 July 2017

Jianhua Zhang

7

1 reference

29 July 2017

language of work or name

English

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publication date

1 February 2010

1 reference

Journal of Biological Chemistry

29 July 2017

1 reference

29 July 2017

285

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29 July 2017

14

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29 July 2017

10497-10507

1 reference

Autophagic cell death: the story of a misnomer

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Acute neonatal glucocorticoid exposure produces selective and rapid cerebellar neural progenitor cell apoptotic death

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Bcl-2 family members: dual regulators of apoptosis and autophagy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Regulation of autophagy by cytoplasmic p53

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Autophagic neuron death in neonatal brain ischemia/hypoxia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Ambra1 regulates autophagy and development of the nervous system

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Autophagy, bafilomycin and cell death: the "a-B-cs" of plecomacrolide-induced neuroprotection

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Autophagic stress in neuronal injury and disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Loss of autophagy in the central nervous system causes neurodegeneration in mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

The coordinate regulation of the p53 and mTOR pathways in cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Inhibition of macroautophagy triggers apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

The role of autophagy during the early neonatal starvation period

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Class III phosphoinositide 3-kinase--Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent but caspase-independent

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Mice deficient in lysosomal acid phosphatase develop lysosomal storage in the kidney and central nervous system

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Multipotent neural cell lines can engraft and participate in development of mouse cerebellum

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856257

Altered regulation of phosphatidylinositol 3-kinase signaling in cathepsin D-deficient brain.

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Neural precursor cells possess multiple p53-dependent apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Bcl-2 family and the central nervous system: from rheostat to real complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Atg5: more than an autophagy factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Growth factor control of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Role of phosphoinositide 3-kinase in the autophagic death of serum-deprived PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Lysosomal release of cathepsins causes ischemic damage in the rat hippocampal slice and depends on NMDA-mediated calcium influx, arachidonic acid metabolism, and free radical production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.103747

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

21 January 2018

1 reference

12 December 2020

Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells

1 reference

12 December 2020

Apoptosis: from morphological types of cell death to interacting pathways

1 reference

12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.103747

1 reference

release_d47ji62bubdhni6odyu7paza6i

29 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/d47ji62bubdhni6odyu7paza6i

24 November 2022

mapped directly with Wikidata item

PMCID

2856257

1 reference

29 July 2017

1 reference