Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity (Q33796227)

29 July 2017

Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity (English)

1 reference

29 July 2017

5

David J Craik

1 reference

29 July 2017

Yen-Hua Huang

1

1 reference

29 July 2017

Michelle L Colgrave

series ordinal

2

1 reference

29 July 2017

Richard J Clark

series ordinal

3

1 reference

29 July 2017

Andrew C Kotze

series ordinal

4

1 reference

29 July 2017

language of work or name

English

0 references

publication date

26 January 2010

1 reference

Journal of Biological Chemistry

29 July 2017

1 reference

29 July 2017

285

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29 July 2017

14

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29 July 2017

10797-10805

1 reference

The biological activity of the prototypic cyclotide kalata b1 is modulated by the formation of multimeric pores

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Circular proteins from Melicytus (Violaceae) refine the conserved protein and gene architecture of cyclotides

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Anthelmintic activity of cyclotides: In vitro studies with canine and human hookworms.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Cyclotides: natural, circular plant peptides that possess significant activity against gastrointestinal nematode parasites of sheep.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Cyclotides as natural anti-HIV agents.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Structural analysis of foot-and-mouth disease virus 3C protease: a viable target for antiviral drugs?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Insecticidal plant cyclotides and related cystine knot toxins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Conformation and mode of membrane interaction in cyclotides. Spatial structure of kalata B1 bound to a dodecylphosphocholine micelle

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Discovery, structure and biological activities of the cyclotides

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Drug resistance in nematodes of veterinary importance: a status report.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Drug resistance in veterinary helminths

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Reversible antifouling effect of the cyclotide cycloviolacin O2 against barnacles

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Twists, knots, and rings in proteins. Structural definition of the cyclotide framework

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Disulfide folding pathways of cystine knot proteins. Tying the knot within the circular backbone of the cyclotides

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Plant cyclotides: circular, knotted peptide toxins.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Biosynthesis and insecticidal properties of plant cyclotides: the cyclic knotted proteins from Oldenlandia affinis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

First cyclotide from Hybanthus (Violaceae).

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Circular proteins in plants: solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Seven novel macrocyclic polypeptides from Viola arvensis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

A biomimetic strategy in the synthesis and fragmentation of cyclic protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Synthesis of proteins by native chemical ligation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Cyclopsychotride A, a biologically active, 31-residue cyclic peptide isolated from Psychotria longipes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

A new method for culture of larvae used in diagnosis of ruminant gastrointestinal strongylosis: comparison with fecal cultures

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856286

Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089854

Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089854

Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Möbius strips exist in nature?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089854

The anthelmintic activity of the cyclotides: natural variants with enhanced activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089854

Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089854

Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089854

Haemonchus contortus utilises catalase in defence against exogenous hydrogen peroxide in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089854

Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089854

Structural and mutagenic analysis of foot-and-mouth disease virus 3C protease reveals the role of the beta-ribbon in proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089854

Squash trypsin inhibitors from Momordica cochinchinensis exhibit an atypical macrocyclic structure

21 January 2018

1 reference

12 December 2020

The role of the cyclic peptide backbone in the anti-HIV activity of the cyclotide kalata B1

1 reference

12 December 2020

Haemonchus contortus: in vitro drug screening assays with the adult life stage

1 reference

12 December 2020

New anthelmintics for livestock: the time is right

1 reference

12 December 2020

Fractionation Protocol for the Isolation of Polypeptides from Plant Biomass

1 reference

12 December 2020

In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.089854

1 reference

release_nkherhrparamlcmf7jsmqm4kcq

29 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nkherhrparamlcmf7jsmqm4kcq

24 November 2022

mapped directly with Wikidata item

PMCID

2856286

1 reference

29 July 2017

1 reference