High-throughput fluorescence assay for small-molecule inhibitors of autophagins/Atg4. (Q33796350)

29 July 2017

title

High-throughput fluorescence assay for small-molecule inhibitors of autophagins/Atg4. (English)

1 reference

29 July 2017

Chih-Wen Shu

1

1 reference

ORCID Public Data File 2021

author name string

Charitha Madiraju

2

1 reference

29 July 2017

Dayong Zhai

3

1 reference

29 July 2017

Kate Welsh

4

1 reference

29 July 2017

Paul Diaz

5

1 reference

29 July 2017

Eduard Sergienko

6

1 reference

29 July 2017

Renata Sano

7

1 reference

29 July 2017

John C Reed

8

1 reference

29 July 2017

publication date

18 January 2011

1 reference

Journal of Biomolecular Screening

29 July 2017

published in

1 reference

29 July 2017

volume

16

1 reference

29 July 2017

issue

2

1 reference

29 July 2017

page(s)

174-182

1 reference

Autophagy: Is It Cancer's Friend or Foe?

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Autophagy: principles and significance in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Autophagy in the eukaryotic cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Dynamics and diversity in autophagy mechanisms: lessons from yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Acetylation targets mutant huntingtin to autophagosomes for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Human cytomegalovirus controls a new autophagy-dependent cellular antiviral defense mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Role of autophagy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Autophagy: assays and artifacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Synthetic substrates for measuring activity of autophagy proteases-autophagins (Atg4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Autophagy is essential for mouse sense of balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Biochemical characteristics of caspases-3, -6, -7, and -8

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

The oxidative mechanism of action of ortho-quinone inhibitors of protein-tyrosine phosphatase alpha is mediated by hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

A balancing act for autophagin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

Active site and catalytic mechanism of phospholipase A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057110392996

21 January 2018

Identifiers

DOI

10.1177/1087057110392996

1 reference

29 July 2017

1 reference