Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells (Q33803438)

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English	Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells (English)

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Europe PubMed Central

29 July 2017

1 reference

based on heuristic

inferred from title

author name string

Helen N Jones

1

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Europe PubMed Central

29 July 2017

Thomas Jansson

2

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Europe PubMed Central

29 July 2017

Theresa L Powell

3

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Europe PubMed Central

29 July 2017

language of work or name

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publication date

11 February 2010

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

59

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Europe PubMed Central

29 July 2017

5

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Europe PubMed Central

29 July 2017

1161-1170

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Europe PubMed Central

29 July 2017

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

30 August 2021

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April 2022 Public Data File from Crossref

copyright status

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Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells

1 reference

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Adiponectin attenuation of endocrine function within human term trophoblast cells

1 reference

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Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases

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APPL1: role in adiponectin signaling and beyond

1 reference

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High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

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Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake

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Peroxisome Proliferators-Activated Receptor (PPAR) Modulators and Metabolic Disorders

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High molecular mass multimer complexes and vascular expression contribute to high adiponectin in the fetus

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Regulation of placental nutrient transport--a review

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Amino acid transporter ATA2 is stored at the trans-Golgi network and released by insulin stimulus in adipocytes

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Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and interleukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes

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APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

1 reference

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Secretion of adiponectin by human placenta: differential modulation of adiponectin and its receptors by cytokines

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Hyperglycemia- and hyperinsulinemia-induced alteration of adiponectin receptor expression and adiponectin effects in L6 myoblasts

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The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex

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Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factor-kappaB, peroxisomal proliferator-activated receptor-gamma and extracellularly regulated k

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Adiponectin and adiponectin receptors

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Expression and regulation of adiponectin and receptor in human and rat placenta

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Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus

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Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells.

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Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1.

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Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

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Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes

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ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism

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Expression and regulation of 4F2hc and hLAT1 in human trophoblasts

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The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

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Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

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Amino acid transport by the cultured human placental trophoblast: effect of insulin on AIB transport

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Effects of glucose, glycerol, 3-hydroxybutyrate, insulin, and leptin on placental growth hormone secretion in placental explants.

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Activation of nuclear factor-kappaB by high molecular weight and globular adiponectin

1 reference

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Opposing effects of adiponectin receptors 1 and 2 on energy metabolism.

1 reference

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Adiponectin sensitizes insulin signaling by reducing p70 S6 kinase-mediated serine phosphorylation of IRS-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857896

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IFPA 2005 Award in Placentology Lecture. Human placental transport in altered fetal growth: does the placenta function as a nutrient sensor? -- a review

1 reference

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Adiponectin expression in human fetal tissues during mid- and late gestation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857896

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Adiponectin is reduced in gestational diabetes mellitus in normal weight women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857896

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Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857896

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Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism

1 reference

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Reappraisal of neonatal clavicular fracture. Relationship between infant size and risk factors

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Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

1 reference

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Purification, Characterization, andin vitroDifferentiation of Cytotrophoblasts from Human Term Placentae*

1 reference

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Changes in placental adipocytokine gene expression associated with gestational diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

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based on heuristic

inferred from PubMed ID database lookup

Adiponectin enhances IL-6 production in human synovial fibroblast via an AdipoR1 receptor, AMPK, p38, and NF-kappa B pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adiponectin induces interleukin-6 production and activates STAT3 in adult mouse cardiac fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triglyceride Hydrolase Activities and Expression of Fatty Acid Binding Proteins in the Human Placenta in Pregnancies Complicated by Intrauterine Growth Restriction and Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of adiponectin receptor 2 reduces diet-induced insulin resistance but promotes type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placental glucose transport and GLUT 1 expression in insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbohydrate metabolism in pregnancy. XVII. Diurnal profiles of plasma glucose, insulin, free fatty acids, triglycerides, cholesterol, and individual amino acids in late normal pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

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based on heuristic

inferred from PubMed ID database lookup

Characterization and regulation of the gene expression of amino acid transport system A (SNAT2) in rat mammary gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20150288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB09-0824

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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