Genetic engineering of recombinant glycoproteins and the glycosylation pathway in mammalian host cells (Q33804543)

29 July 2017

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title

Genetic engineering of recombinant glycoproteins and the glycosylation pathway in mammalian host cells (English)

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29 July 2017

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Grabenhorst E

1

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29 July 2017

Schlenke P

2

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29 July 2017

Pohl S

3

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29 July 2017

Nimtz M

4

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29 July 2017

Conradt HS

5

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29 July 2017

1 February 1999

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29 July 2017

Glycoconjugate Journal

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29 July 2017

16

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29 July 2017

2

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29 July 2017

81-97

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https://scigraph.springernature.com/pub.10.1023/a:1026466408042

29 July 2017

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cites work

Bovine colostrum CMP-NeuAc:Gal beta(1-->4)GlcNAc-R alpha(2-->6)-sialyltransferase is involved in the synthesis of the terminal NeuAc alpha(2-->6)GalNAc beta(1-->4)GlcNAc sequence occurring on N-linked glycans of bovine milk glycoproteins

1 reference

12 December 2020

Comparative study of the asparagine-linked sugar chains of human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells

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12 December 2020

Biological roles of oligosaccharides: all of the theories are correct

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12 December 2020

Inflammation-induced expression of sialyl LewisX is not restricted to alpha1-acid glycoprotein but also occurs to a lesser extent on alpha1-antichymotrypsin and haptoglobin

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12 December 2020

Branch specificity of bovine colostrum CMP-sialic acid: Gal beta 1----4GlcNAc-R alpha 2----6-sialyltransferase. Sialylation of bi-, tri-, and tetraantennary oligosaccharides and glycopeptides of the N-acetyllactosamine type.

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12 December 2020

N-glycosylation of recombinant human interferon-gamma produced in different animal expression systems

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12 December 2020

Trafficking and localization studies of recombinant alpha1, 3-fucosyltransferase VI stably expressed in CHO cells

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12 December 2020

Getting the glycosylation right: implications for the biotechnology industry

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12 December 2020

Construction of stable BHK-21 cells coexpressing human secretory glycoproteins and human Gal(beta 1-4)GlcNAc-R alpha 2,6-sialyltransferase alpha 2,6-linked NeuAc is preferentially attached to the Gal(beta 1-4)GlcNAc(beta 1-2)Man(alpha 1-3)-branch of

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12 December 2020

Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes

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12 December 2020

Characterization of recombinant human antithrombin III synthesized in Chinese hamster ovary cells

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12 December 2020

Isolation and expression of a cDNA clone encoding a bovine UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase.

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12 December 2020

Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion

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12 December 2020

'Brain-type' N-glycosylation of asialo-transferrin from human cerebrospinal fluid

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12 December 2020

Acceptor specificity of different length constructs of human recombinant alpha 1,3/4-fucosyltransferases. Replacement of the stem region and the transmembrane domain of fucosyltransferase V by protein A results in an enzyme with GDP-fucose hydrolyzi

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12 December 2020

Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant

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12 December 2020

The oligosaccharides of glycoproteins: bioprocess factors affecting oligosaccharide structure and their effect on glycoprotein properties

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12 December 2020

In vivo specificity of human alpha1,3/4-fucosyltransferases III-VII in the biosynthesis of LewisX and Sialyl LewisX motifs on complex-type N-glycans. Coexpression studies from bhk-21 cells together with human beta-trace protein

1 reference

12 December 2020

Expression of distinct fucosylated oligosaccharides and carbohydrate-mediated adhesion efficiency directed by two different alpha-1,3-fucosyltransferases. Comparison of E- and L-selectin-mediated adhesion

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12 December 2020

Beta1,4-N-acetylgalactosaminyltransferase (GM2 synthase) is released from Golgi membranes as a neuraminidase-sensitive, disulfide-bonded dimer by a cathepsin D-like protease

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12 December 2020

Novel Asn-linked oligosaccharides terminating in GalNAc beta (1-->4)[Fuc alpha (1-->3)]GlcNAc beta (1-->.) are present in recombinant human protein C expressed in human kidney 293 cells

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12 December 2020

Two soluble glycosyltransferases glycosylate less efficiently in vivo than their membrane bound counterparts.

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12 December 2020

Transfer and expression of a murine UDP-Gal:beta-D-Gal-alpha 1,3-galactosyltransferase gene in transfected Chinese hamster ovary cells. Competition reactions between the alpha 1,3-galactosyltransferase and the endogenous alpha 2,3-sialyltransferase

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12 December 2020

Comparative study of the asparagine-linked sugar chains of natural human interferon-beta 1 and recombinant human interferon-beta 1 produced by three different mammalian cells.

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12 December 2020

Enzymatic characterization of human alpha1,3-fucosyltransferase Fuc-TVII synthesized in a B cell lymphoma cell line

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12 December 2020

Determination of the glycosylation patterns, disulfide linkages, and protein heterogeneities of baculovirus-expressed mouse interleukin-3 by mass spectrometry

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12 December 2020

Cloning of a human alpha(1,3)-fucosyltransferase gene that encodes ELFT but does not confer ELAM-1 recognition on Chinese hamster ovary cell transfectants.

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12 December 2020

The cloning and expression of a human alpha-1,3 fucosyltransferase capable of forming the E-selectin ligand

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12 December 2020

Inflammation-induced expression of sialyl Lewis X-containing glycan structures on alpha 1-acid glycoprotein (orosomucoid) in human sera

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12 December 2020

Golgi localization of glycosyltransferases: more questions than answers

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12 December 2020

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12 December 2020

A soluble form of alpha1,3-galactosyltransferase functions within cells to galactosylate glycoproteins

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12 December 2020

Localization of proteins to the Golgi apparatus

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12 December 2020

Structural studies of the carbohydrate chains of human gamma-interferon

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12 December 2020

Golgi division and membrane traffic

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12 December 2020

Environmental effects on protein glycosylation

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12 December 2020

Identification of the full-length coding sequence for human galactosyltransferase (beta-N-acetylglucosaminide: beta 1,4-galactosyltransferase)

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12 December 2020

Molecular characterization of eukaryotic polysialyltransferase-1

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12 December 2020

Structures of sialylated oligosaccharides of human erythropoietin expressed in recombinant BHK-21 cells

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12 December 2020

Hypoglycosylation of a brain glycoprotein (beta-trace protein) in CDG syndromes due to phosphomannomutase deficiency and N-acetylglucosaminyl-transferase II deficiency

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12 December 2020

In vitro alpha1-3 or alpha1-4 fucosylation of type I and II oligosaccharides with secreted forms of recombinant human fucosyltransferases III and VI

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12 December 2020

Isolation of a cDNA encoding a murine UDPgalactose:beta-D-galactosyl- 1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase: expression cloning by gene transfer

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12 December 2020

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12 December 2020

Expression of human interleukin-2 in recombinant baby hamster kidney, Ltk-, and Chinese hamster ovary cells. Structure of O-linked carbohydrate chains and their location within the polypeptide

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12 December 2020

ELFT: a gene that directs the expression of an ELAM-1 ligand

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12 December 2020

Molecular characterization of beta-trace protein in human serum and urine: a potential diagnostic marker for renal diseases.

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12 December 2020

A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase

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12 December 2020

Carbohydrate structure of erythropoietin expressed in Chinese hamster ovary cells by a human erythropoietin cDNA

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12 December 2020

Structure of the carbohydrate moiety of human interferon-beta secreted by a recombinant Chinese hamster ovary cell line

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12 December 2020

Acceptor specificity of GDP-Fuc:Gal beta 1-->4GlcNAc-R alpha 3-fucosyltransferase VI (FucT VI) expressed in insect cells as soluble, secreted enzyme

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12 December 2020

Cholesterol and the Golgi apparatus

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12 December 2020

Leukocyte trafficking mediated by selectin-carbohydrate interactions

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12 December 2020

Molecular cloning, expression, chromosomal assignment, and tissue-specific expression of a murine alpha-(1,3)-fucosyltransferase locus corresponding to the human ELAM-1 ligand fucosyl transferase.

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12 December 2020

NMR investigations of the N-linked oligosaccharides at individual glycosylation sites of human lutropin

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12 December 2020

Structures and functions of the sugar chains of glycoproteins

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12 December 2020

Biosynthesis and secretion of human interleukin 2 glycoprotein variants from baculovirus-infected Sf21 cells. Characterization of polypeptides and posttranslational modifications

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12 December 2020

Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes

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12 December 2020

Structural Analysis of the Sialylated N- and O-Linked Carbohydrate Chains of Recombinant Human Erythropoietin Expressed in Chinese Hamster Ovary Cells. Sialylation Patterns and Branch Location of Dimeric N-acetyllactosamine Units

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12 December 2020

Carbohydrate structures of beta-trace protein from human cerebrospinal fluid: evidence for "brain-type" N-glycosylation

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12 December 2020

Acceptor specificity of the human leukocyte alpha3 fucosyltransferase: role of FucT-VII in the generation of selectin ligands.

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12 December 2020

Selectins and their ligands: current concepts and controversies.

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12 December 2020

Selectin-carbohydrate interactions and the initiation of the inflammatory response

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12 December 2020

Stable expression of the Golgi form and secretory variants of human fucosyltransferase III from BHK-21 cells. Purification and characterization of an engineered truncated form from the culture medium

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12 December 2020

Complete cDNA sequence encoding human beta-galactoside alpha-2,6-sialyltransferase

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12 December 2020

Complementary DNA cloning for galactosyltransferase associated with tumor and determination of antigenic epitopes recognized by specific monoclonal antibodies

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12 December 2020

Action of rat liver Gal beta 1-4GlcNAc alpha(2-6)-sialyltransferase on Man beta 1-4GlcNAc beta-OMe, GalNAc beta 1-4GlcNAc beta-OMe, Glc beta 1-4GlcNAc beta-OMe and GlcNAc beta 1-4GlcNAc beta-OMe as synthetic substrates

1 reference

12 December 2020

Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in embryonic brain

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12 December 2020

Primary structure of beta-galactoside alpha 2,6-sialyltransferase. Conversion of membrane-bound enzyme to soluble forms by cleavage of the NH2-terminal signal anchor.

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12 December 2020

Secretion of glycosylated human interleukin-2 by recombinant mammalian cell lines

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12 December 2020

Studies on the effect of inflammation on rat liver and serum sialyltransferase. Evidence that inflammation causes release of Gal beta 1 leads to 4GlcNAc alpha 2 leads to 6 sialyltransferase from liver

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12 December 2020

Identifiers

DOI

10.1023/A:1026466408042

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Dimensions Publication ID

29 July 2017

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