Cancer and the tumor microenvironment: a review of an essential relationship (Q33806357)

29 July 2017

1 reference

title

Cancer and the tumor microenvironment: a review of an essential relationship (English)

1 reference

29 July 2017

Flaubert Mbeunkui

1

1 reference

29 July 2017

Donald J Johann

series ordinal

2

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29 July 2017

publication date

14 December 2008

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Cancer Chemotherapy and Pharmacology

29 July 2017

published in

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29 July 2017

volume

63

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29 July 2017

issue

4

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29 July 2017

page(s)

571-582

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Precision proteomics: the case for high resolution and high mass accuracy

29 July 2017

cites work

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Differential proteome analysis of conditioned media to detect Smad4 regulated secreted biomarkers in colon cancer

4 July 2018

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A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer

4 July 2018

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Stat3 regulates genes common to both wound healing and cancer

4 July 2018

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Metalloproteinases and their inhibitors in tumor angiogenesis

4 July 2018

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Stable isotope labeling with amino acids in cell culture (SILAC) for studying dynamics of protein abundance and posttranslational modifications

4 July 2018

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Atrasentan: targeting the endothelin axis in prostate cancer

4 July 2018

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Thalidomide in solid tumours: the resurrection of an old drug

4 July 2018

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Friends or foes - bipolar effects of the tumour stroma in cancer

4 July 2018

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Integrin signalling during tumour progression

4 July 2018

1 reference

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Combretastatin A4 phosphate: background and current clinical status

4 July 2018

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Imatinib as a paradigm of targeted therapies

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Molecular characterization of the tumor microenvironment in breast cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Obesity, adipocytokines, and insulin resistance in breast cancer

4 July 2018

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Tumor suppressor Smad4 mediates downregulation of the anti-adhesive invasion-promoting matricellular protein SPARC: Landscaping activity of Smad4 as revealed by a "secretome" analysis.

4 July 2018

1 reference

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

4 July 2018

1 reference

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Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis

4 July 2018

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Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

4 July 2018

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A proteomic analysis of human bile

4 July 2018

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Proteases, extracellular matrix, and cancer: a workshop of the path B study section

4 July 2018

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Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis

4 July 2018

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The STATs of cancer--new molecular targets come of age

4 July 2018

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TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

4 July 2018

1 reference

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Integrins: roles in cancer development and as treatment targets

4 July 2018

1 reference

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Quantitative proteomic analysis of proteins released by neoplastic prostate epithelium

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Drug resistance and the microenvironment: nature and nurture

4 July 2018

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Central obesity and breast cancer risk: a systematic review.

4 July 2018

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Point: Proteomic patterns in biological fluids: do they represent the future of cancer diagnostics?

4 July 2018

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The two faces of transforming growth factor beta in carcinogenesis

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin

4 July 2018

1 reference

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PDGF receptors as cancer drug targets

4 July 2018

1 reference

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Angiogenesis in health and disease

4 July 2018

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A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer

4 July 2018

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The case for early detection

4 July 2018

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Proteome analysis of low-abundance proteins using multidimensional chromatography and isotope-coded affinity tags

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways

4 July 2018

1 reference

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Neovastat--a novel antiangiogenic drug for cancer therapy

4 July 2018

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4 July 2018

Inflammation and cancer

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4 July 2018

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Concomitant determination of absolute values of cellular protein amounts, synthesis rates, and turnover rates by quantitative proteome profiling.

4 July 2018

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VEGF-Trap: a VEGF blocker with potent antitumor effects

4 July 2018

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Cilengitide targeting of alpha(v)beta(3) integrin receptor synergizes with radioimmunotherapy to increase efficacy and apoptosis in breast cancer xenografts

4 July 2018

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Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

4 July 2018

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The role of osteopontin in breast cancer: clinical and experimental studies

4 July 2018

1 reference

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Celecoxib: a specific COX-2 inhibitor with anticancer properties

4 July 2018

1 reference

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Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

4 July 2018

1 reference

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The metastasis gene osteopontin: a candidate target for cancer therapy

4 July 2018

1 reference

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The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent

4 July 2018

1 reference

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A proteomic approach to the identification of lung cancer markers

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

The microenvironment of the tumour-host interface

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Down-regulation of galectin-3 suppresses tumorigenicity of human breast carcinoma cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Infections as a major preventable cause of human cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

4 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Targeted inhibition of osteopontin expression in the mammary gland causes abnormal morphogenesis and lactation deficiency

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Altered wound healing in mice lacking a functional osteopontin gene (spp1).

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Transforming growth factor production by chemically transformed cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Electrospray ionization for mass spectrometry of large biomolecules

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

The tumour microenvironment as a target for chemoprevention.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

A Standard Operating Procedure (SOP) for the preparation of intra- and extracellular proteins of Clostridium acetobutylicum for proteome analysis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

The evolution of thalidomide and its IMiD derivatives as anticancer agents

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Comparison of protein precipitation methods for sample preparation prior to proteomic analysis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer a

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

High levels of TIMP-2 correlate with adverse prognosis in breast cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Comprehensive Proteomic Analysis of Human Pancreatic Juice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858592

Galectin-3 overexpression protects from apoptosis by improving cell adhesion properties

30 October 2018

1 reference

12 December 2020

Osteopontin-induced, integrin-dependent migration of human mammary epithelial cells involves activation of the hepatocyte growth factor receptor (Met)

1 reference

12 December 2020

Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potentials

1 reference

12 December 2020

Expression of galectin-3 in fine-needle aspirates as a diagnostic marker differentiating benign from malignant thyroid neoplasms

1 reference

12 December 2020

Therapeutic targeting of the tumor microenvironment

1 reference

12 December 2020

10.1007/S00280-008-0881-9

Identifiers

DOI

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference